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ML 7

ML 7 structure

ML 7 

structure
  • CAS No:

    109376-83-2

  • Formula:

    C15H17IN2O2S

  • Chemical Name:

    ML 7

  • Synonyms:

    1H-1,4-Diazepine,hexahydro-1-[(5-iodo-1-naphthalenyl)sulfonyl]-;Hexahydro-1-[(5-iodo-1-naphthalenyl)sulfonyl]-1H-1,4-diazepine;ML 7

Description

ML-7 is an N-sulfonyldiazepane resullting from the formal condensation of 5-iodo-1-naphthylsulfonic acid with one of the nitrogens of 1,4-diazepane. It is a selective inhibitor of myosin light chain kinase (EC 2.7.11.18). It has a role as an EC 2.7.11.18 (myosin-light-chain kinase) inhibitor. It is an organoiodine compound and a N-sulfonyldiazepane.

ML 7 Basic Attributes

416.27700

416.28

E2C2LB77BF

DTXSID60148917

2933990090

Characteristics

57.79000

3.77590

1.634g/cm3

542.7ºC

282ºC

1.665

-20ºC

7.71E-12mmHg at 25°C

Safety Information

3

Drug Information

Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. (See all compounds classified as Enzyme Inhibitors.)

1-(5-iodonaphthalene-1-sulfonyl)-1H-hexahydro-1,4-diazepine hydrochloride

Computed Properties

Molecular Weight:416.3
XLogP3:2.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:416.00555
Monoisotopic Mass:416.00555
Topological Polar Surface Area:57.8
Heavy Atom Count:21
Complexity:451
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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