Rioprostil
-
Rioprostil
structure -
-
CAS No:
77287-05-9
-
Formula:
C21H38O4
-
Chemical Name:
Rioprostil
-
Synonyms:
Prost-13-en-9-one,1,11,16-trihydroxy-16-methyl-,(11α,13E)-;(11α,13E)-1,11,16-Trihydroxy-16-methylprost-13-en-9-one;Rioprostil;RWJ 15927;Rostil;Bay-o 6893;ORF 15927;TR 4698
-
CAS No:
Description
Rioprostil is an aliphatic alcohol.|A synthetic methylprostaglandin E1 analog that reduces gastric acid secretion and enhances the gastric mucus-bicarbonate barrier. It is effective in the therapy of gastric ulcers and gives significant protection against NSAID-induced gastric mucosal damage. The drug also prevents cyclosporin A-induced damage to endocrine and exocrine pancreatic secretions. It shows a low order of acute toxicity and there is no evidence of embryotoxicity, fetotoxicity, teratogenicity, or mutagenicity in animal studies.
Drug Information
Various agents with different action mechanisms used to treat or ameliorate PEPTIC ULCER or irritation of the gastrointestinal tract. This has included ANTIBIOTICS to treat HELICOBACTER INFECTIONS; HISTAMINE H2 ANTAGONISTS to reduce GASTRIC ACID secretion; and ANTACIDS for symptomatic relief. (See all compounds classified as Anti-Ulcer Agents.)
ORF 15927
Computed Properties
Molecular Weight:354.5
XLogP3:3.5
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:13
Exact Mass:354.27700969
Monoisotopic Mass:354.27700969
Topological Polar Surface Area:77.8
Heavy Atom Count:25
Complexity:407
Defined Atom Stereocenter Count:3
Undefined Atom Stereocenter Count:1
Defined Bond Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Request for Quotation