Idazoxan
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Idazoxan
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CAS No:
79944-58-4
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Formula:
C11H12N2O2
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Chemical Name:
Idazoxan
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Synonyms:
1H-Imidazole,2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-;2-Imidazoline,2-(1,4-benzodioxan-2-yl)-;1,4-Benzodioxin,1H-imidazole deriv.;2-(2,3-Dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-1H-imidazole;Idazoxan;(±)-Idazoxan;dl-Idazoxan;Racemic idazoxan;84720-37-6
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CAS No:
Description
Idazoxan is a benzodioxine that is 2,3-dihydro-1,4-benzodioxine in which one of the hydrogens at position 2 has been replaced by a 4,5-dihydro-1H-imidazol-2-yl group. It has a role as an alpha-adrenergic antagonist. It is a benzodioxine and a member of imidazolines.|Idazoxan has been used in trials studying the basic science of Molecular Imaging, Alzheimer Disease, and Major Depressive Disorder.|A benzodioxane-linked imidazole that has alpha-2 adrenoceptor antagonist activity.
Drug Information
Drugs that bind to and block the activation of ADRENERGIC ALPHA-2 RECEPTORS. (See all compounds classified as Adrenergic alpha-2 Receptor Antagonists.)
Hydrochloride, Idazoxan
Computed Properties
Molecular Weight:204.22
XLogP3:0.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:204.089877630
Monoisotopic Mass:204.089877630
Topological Polar Surface Area:42.8
Heavy Atom Count:15
Complexity:267
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes