Diltiazem malate
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Diltiazem malate
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CAS No:
144604-00-2
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Formula:
C26H32N2O9S
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Chemical Name:
Diltiazem malate
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Synonyms:
Diltiazem malate;Diltiazem malate [USAN];UNII-14Y6444DRP;144604-00-2;14Y6444DRP;144604-00-2 (MALATE);Diltiazem malate (USAN);(2S,3S)-5-(2-(dimethylamino)ethyl)-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepin-3-yl acetate (S)-2-hydroxysuccinate;MK-793;Tiamate (TN)
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CAS No:
Description
Diltiazem Malate is a malate salt of diltazem, a benzothiazepine calcium channel blocking agent. Diltiazem inhibits the transmembrane influx of extracellular calcium ions into select myocardial and vascular smooth muscle cells, causing dilatation of coronary and systemic arteries and decreasing myocardial contractility. Because of its vasodilatory activity, this agent has been shown to improve the microcirculation in some tumors, thereby potentially improving the delivery of antineoplastic agents to tumor cells.|A benzothiazepine derivative with vasodilating action due to its antagonism of the actions of CALCIUM ion on membrane functions.
Drug Information
Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS. (See all compounds classified as Antihypertensive Agents.)|A class of drugs that act by selective inhibition of calcium influx through cellular membranes. (See all compounds classified as Calcium Channel Blockers.)|Agents that affect the rate or intensity of cardiac contraction, blood vessel diameter, or blood volume. (See all compounds classified as Cardiovascular Agents.)|Drugs used to cause dilation of the blood vessels. (See all compounds classified as Vasodilator Agents.)
Aldizem
Diltiazem malate Use and Manufacturing
Human Drugs -> FDA Approved Drug Products with Therapeutic Equivalence Evaluations (Orange Book) -> Active Ingredients
Learn More Other Chemicals
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DIBUTYL TIN MALATE
15535-69-0
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Malate dehydrogenase (NADP, decarboxylating)
9028-47-1
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Di(2-ethylhexyl) malate
56235-92-8
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DIALLYL MALATE Formula
32099-14-2
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Magnesium malate Formula
869-06-7
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Deacetyl Diltiazem N-Oxide Formula
122619-90-3
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Malate dehydrogenase (NAD) Structure
9001-64-3
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Deacetyl-O-demethyl Diltiazem Hydrochloride Structure
96252-32-3
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What is DIBUTYLOCTYL MALATE
399551-19-0
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What is Diltiazem
42399-41-7
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