S-Ethyl dipropylthiocarbamate

189.32

189.32

212-073-8

R7PI3287F4

0469

40486

2902|2992|2757

DTXSID1024091

Colorless liquid|Yellow liquid (technical)

29341000

45.6

3.20

Clear colorless Liquid

0.955 g/cm³ @ Temp: 30 °C

<25 °C

127 °C @ Press: 20 Torr

116 °C

1.479

H2O: 0.375 g/100 mL

0-6°C

Vapour pressure, Pa at 25°C: 4.5

Relative vapour density (air = 1): 6.5

Oral-Rat  LD50: 916 mg/kg; Oral-Mouse LD50: 750 mg/kg

Combustion produces toxic nitrogen oxide and sulfur oxide gas

Aromatic odor

3.18e-11 cm3/molecule*sec

Hydrolyzed by strong acids on heating.|Hydroxyl radical rate constant= 3.2X10-11 cu cm/molecule-sec @ 25 °C

Water insoluble. Slowly decomposes in water to form carbon disulfide and propyl amine. Such decompositions are accelerated by acids.

Thiocarbamate Esters and Salts/Dithiocarbamate Esters and Salts

ETHYL DIPROPYLTHIOCARBAMATE may generate flammable gases with aldehydes, nitrides, and hydrides. Incompatible with acids, peroxides, and acid halides.

NON-CORROSIVE

III

6.1(b)

2902

3

22

2-23

FA4550000

Xn

The warehouse is ventilated, low temperature and dry; stored and transported separately from food materials

Stable. Incompatible with strong oxidizing agents.

P264, P270, P301+P312, P330, P501

H302

SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.|EPTC is combustible and could be incinerated. Recommendable method: Incineration. Peer-review: Incineration in a unit with effluent gas scrubbing is recommendable for large amt. (Peer-review conclusions of an IRPTC expert consultation (May 1985))|No acceptable chemical detoxification is available. Empty containers should be triple rinsed. "Triple rinse" means the flushing of containers three times, each time using a volume of the normal diluent equal to approx ten percent of the container's capacity, and adding the rinse liquid to the spray mixture or disposing of it by a method prescribed for disposing of the pesticide.

Flash point data are not available for this chemical, but it is probably combustible. (NTP, 1992)|Combustible. Liquid formulations containing organic solvents may be flammable. Gives off irritating or toxic fumes (or gases) in a fire.

|Warning|H302: Harmful if swallowed [Warning Acute toxicity, oral]|P264, P270, P301+P312, P330, and P501|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|Aggregated GHS information provided by 199 companies from 2 notifications to the ECHA C&L Inventory.|P201, P202, P264, P270, P281, P301+P312, P308+P313, P330, P405, and P501

Fires involving this compound should be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)|Use water spray, foam, powder, carbon dioxide.

Excerpt from ERG Guide 151 [Substances - Toxic (Non-combustible)]: As an immediate precautionary measure, isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids. SPILL: Increase, in the downwind direction, as necessary, the isolation distance shown above. FIRE: If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2016)

SMALL SPILLS AND LEAKAGE: If you spill this chemical, use absorbent paper to pick up all liquid spill material. Your contaminated clothing and absorbent paper should be sealed in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with alcohol followed by washing with a strong soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned. STORAGE PRECAUTIONS: You should store this material in a refrigerator. (NTP, 1992)

MINIMUM PROTECTIVE CLOTHING: If Tyvek-type disposable protective clothing is not worn during handling of this chemical, wear disposable Tyvek-type sleeves taped to your gloves. RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter. (NTP, 1992)

Avoid eye, skin contact

/SRP: Exposure to dusts, sprays, solutions, wettable powder suspensions or emulsions of these agents may lead to skin and mucous membrane irritation./

Do NOT wash away into sewer. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.

Provision to contain effluent from fire extinguishing. Separated from food and feedstuffs. Ventilation along the floor.

A harmful contamination of the air will not or will only very slowly be reached on evaporation of this substance at 20 °C; on spraying or dispersing, however, much faster.

The substance may cause effects on the central nervous system.

NO open flames.

PREVENT GENERATION OF MISTS! AVOID EXPOSURE OF ADOLESCENTS AND CHILDREN!

Use ventilation, local exhaust or breathing protection.

Protective gloves.

Wear safety spectacles or eye protection in combination with breathing protection.

During its use as a herbicide, eptam is released(1) via ground sprayers, cultivation equipment, soil injection and irrigation(2). Eptam may undergo surface runoff via rainfall(3). Herbicidal application of eptam can result in contamination of surrounding areas through accidental spills and spray drift(4,5).

LOSSES OF SOIL APPLIED EPTC FROM SOIL WERE INCR BY AIR MOVEMENT OVER THE SOIL SURFACE. SOIL COMPOSITION & HERBICIDE FORMULATION ALSO INFLUENCED ITS RATE OF LOSS.|SOIL: In 1989, the mean concn of eptam in soil at agrochemical facilities in Illinois was determined to be 110 ug/kg(1).

INDOOR AIR: Eptam was detected in the air inside of a commercial pesticide storage building at a concn of 20 ng/cu m air during March 1-April 8, 1983(1).|RURAL/REMOTE: The maximum concn and percent detections of eptam in air over the Mississippi River from New Orleans, LA to St. Paul, MN during June 1994 was 1.5 ng/cu m and 30%, respectively(1).

moderately toxic

ANTAGONISTIC INTERACTION BETWEEN 2,4-D ([2,4-DICHLOROPHENOXY]ACETIC ACID) & EPTC OR OTHER THIOCARBAMATES HAS BEEN REPORTED ... . GENERALLY, THE INHIBITION OF GROWTH IS RELATED TO THE CONCN OF THIOCARBAMATES, & THIS INHIBITION CAN BE REVERSED BY 2,4-D.|THE HERBICIDE SAFENER N-DICHLOROACETYL-1-OXA-4-AZA-SPIRO-4,5-DECANE IS OF SIMILAR EFFICIENCY AS THE EXTENSIVELY USED N,N-DIALLYL-2,2-DICHLOROACETAMIDE & STRUCTURALLY RELATED 3-(DICHLOROACETYL)-2,2-DIMETHYL-1,3-OXAZOLIDINE IN REDUCING EPTC INJURY TO MAIZE.

LD50 Rat male albino oral 2550 mg/kg|LD50 Rat oral 916 mg/kg|LD50 Rat skin 3200 mg/kg|LD50 Mouse oral 750 mg/kg|For more Non-Human Toxicity Values (Complete) data for EPTAM (7 total), please visit the HSDB record page.

Eptam's use as an herbicide(1) is expected to result in its direct release to the environment(SRC). Based on available pesticide survey usage information for the years of 1987 through 1996, an annual estimate of eptam total domestic usage averaged approximately 20 million pounds for almost 6 million acres treated(2).

TERRESTRIAL FATE: Based on a classification scheme(1), Koc values of 136-280(2-4) indicate that eptam is expected to have moderate mobility in soil(SRC). The leaching of eptam in soil decreases as clay and organic matter increases(2). Volatilization of eptam from moist soil surfaces is expected to be an important fate process(SRC), given an estimated Henry's Law constant of 1.6X10-5 atm-cu m/mole(SRC), derived from its vapor pressure, 2.4X10-2 mm Hg(12), and water solubility, 375 mg/l(5). Eptam has a half-life in wet soil of 3.4 hrs if eptam is applied when the surface is wet at the time of application and is not immediately incorporated into the soil(6). Microbial breakdown is reported as a main removal process of eptam from soil(2). In a loam soil at 25 °C inoculated with eptam degraders, approximately 100% eptam was removed from the soil within 15 days; 45% of the loss was due to biodegradation; 55% removal by volatilization was reported in the sterile sample(7). The biodegradation half-life of eptam (initial concn of 5 ppm) at 25 °C in Regina heavy clay soil (pH 7.5) and Weyburn loam (pH 7.0) was 4-5 wks and 4 wks, respectively(8). The half-life in moist loam soil at 21-27 °C is about 1 week(2). Eptam was reported to persist in soil for 4 wks(9). According to the US Dept of Agriculture's Pesticide Properties Database, the soil half-life of eptam is 6 days(10). Soil biodegradation studies suggest that eptam is somewhat more persistent under anaerobic conditions with half-lives of 31 to 127 days(4). Eptam was applied to soil at a depth of 10 cm; 13% of the initial mass of eptam volatilized in 10 days(11).|AQUATIC FATE: Based on a classification scheme(1), Koc values of 136 to 280(2-4) indicate that eptam is expected to adsorb to suspended solids and sediment(SRC). Volatilization from water surfaces is expected(5), based upon an estimated Henry's Law constant of 1.6X10-5 atm-cu m/mole(SRC), derived from its vapor pressure, 2.4X10-2 mm Hg(8), and water solubility, 375 mg/l(6). Using this Henry's Law constant and an estimation method(3), volatilization half-lives for a model river and model lake are 3 and 28 days, respectively(SRC). Eptam does not undergo hydrolysis under environmentally relevant conditions (pH 5 to 9)(4). Biodegradation of eptam is expected to occur in aqueous systems based on its biodegradation in soil(4). According to a classification scheme(7), a range of experimental BCFs of 37 to 110(4), suggest the potential for bioconcentration in aquatic organisms is moderate to high(SRC).|ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), eptam, which has a vapor pressure of 2.4X10-2 mm Hg at 25 °C(2), is expected to exist solely in the vapor-phase in the ambient atmosphere(SRC). Vapor-phase eptam is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be 14 hrs(SRC), calculated from its rate constant of 3.18X10-11 cu cm/molecule-sec at 25 °C(3). Physical removal from air by wet deposition (dissolution in clouds, rainfall, etc) occurs(SRC); eptam has been detected in widespread rainwater monitoring studies(4,5). Degradation rates associated with rainwater and clouds are unknown(SRC); these monitoring studies suggest that widespread atmospheric dispersal is possible(4).

SOIL SAMPLES TREATED WITH THIRAM, EPTAM, OR VERNAM YIELDED SECONDARY AMINES, BUT NO NITROSAMINES.|The rate constant for the vapor-phase reaction of eptam with photochemically-produced hydroxyl radicals is 3.18X10-11 cu cm/molecule-sec at 25 °C(1). This corresponds to an atmospheric half-life of approximately 14 hrs at an atmospheric concn of 5X10+5 hydroxyl radicals per cu cm(2). Eptam does not undergo hydrolysis under environmentally relevant conditions (pH 5 to 9)(3) nor directly photolyze due to the lack of absorption in the environmental UV spectrum (>290 nm)(SRC).

The bioaccumulation and elimination of 14C-EPTC by bluegill sunfish was investigated in a dynamic flow-through system, where the fish were exposed for 28 days to radiolabeled 14C-eptam at 22 °C, followed by depuration in EPTC free water for 14 days(1). Bioconcentration factors were 37, 60, and 110, respectively, in the edible, whole fish, and non-edible fish tissues(1). According to a classification scheme(2), the whole-fish BCF value suggests the potential for bioconcentration in aquatic organisms is moderate(SRC).

239.88 L/kg|The avg Koc of eptam is 200; and measured values of Koc range from 170-280(1). Experimentally-determined Kocs are: 283 in soil with 1.0-4.5% organic content and 109 in soil with 30% organic content(2). Koc values for eptam were measured for 4 soil series with various organic matter (OM%) levels(1): e.g., Atterberry (2.2%), Columbia (1.1%), Keeton (0.3%), and Sorrento (1.8%); the Koc values were 136, 146, 264, and 143, respectively(3). According to a classification scheme(4), these Koc values suggest that eptam is expected to have moderate to high mobility in soil(SRC). Eptam has low affinity for binding to soil suggesting a potential to leach to groundwater(3).

The Henry's Law constant for eptam is estimated as 1.6X10-5 atm-cu m/mole(SRC) derived from its vapor pressure, 2.4X10-2 mm Hg(1), and water solubility, 375 mg/l(2). This Henry's Law constant indicates that eptam is expected to volatilize from water surfaces(3). Based on this Henry's Law constant, the volatilization half-life from a model river (1 m deep, flowing 1 m/sec, wind velocity of 3 m/sec)(3) is estimated as 3 days(SRC). The volatilization half-life from a model lake (1 m deep, flowing 0.05 m/sec, wind velocity of 0.5 m/sec)(3) is estimated as 28 days(SRC). Eptam's estimated Henry's Law constant(1,2) indicates that volatilization from moist soil surfaces may occur(SRC). Eptam is readily lost from soil by volatilization when the surface is wet at the time of application and the herbicide is not immediately incorporated into the soil(1). After spraying eptam at a rate of 3.2 lb/ac on the surface of a loamy sand with a moisture content of 16-17% at 32 °C, 78% and 86% vapor loss was observed in 2 and 6 hrs, respectively(4). Using a vapor trapping apparatus, the ave eptam vapor loss was determined to be 24% in 30 minutes after eptam was applied to the surface of a moist loamy sand at a rate of 3 lb/ac and 21-32 °C(4). Assuming that surface-applied eptam dissipates from soil mainly by volatilization(5), a volatilization half-life from soil can be estimated to be about 3 hrs based on an estimated dissipation rate of 5 days-1(5). Eptam was applied to soil with no water flow occurring at a depth of 10 cm and 13% of the initial mass of eptam volatilized in 10 days(6). Eptam is not expected to volatilize from dry soil surfaces based upon its vapor pressure(1).

SURFACE WATER: Eptam was detected in lake/reservoir surface water at 10 of 78 stations in the United States at an ave concn of 0.014 ug/l(1). During 1986 to 1991, eptam maximum concns in Lake Erie tributaries, which drain agricultural watersheds, were: 4 ug/l in the Maumee River, 14 ug/l in the Sandusky River, 6 ug/l in Honey Creek, 8 ug/l in Rock Creek, 21 ug/l in Lost Creek, 1 ug/l in the Cuyahoga River, and 0.1 ug/l in the Raisin River(2). Eptam was detected in Shell Creek, a tributary to the Platte River in NE, at a concn range of 0.1-1 ug/l in 7 samples taken about 96 hrs after a spring rainstorm; no eptam was detected in the creek prior to the storm(3). During the months May-to-Aug 1981-85, the eptam concn was 0.1 ug/l in 1 of 41 samples drawn at the mouth of the Saugeen River, Ontario, Canada(4). In 1977, eptam was qualitatively identified in water from Lake Erie(5).|SURFACE WATER: The frequencies (4 to 25%) of reported eptam detection in surface water depended on type of site or water body sampled(1). The states with the highest frequencies of detection in surface water correspond with the regions with greatest eptam use(1). Maximum eptam concns in two databases (NAWQA and STORET) depended on site type (eg, stream, lake), and ranged from 0.037 to 40 ug/l and 0.001 to 10.0 ug/l, respectively(1). In the STORET database, the concn of eptam ranged from 0.0 to 10.0 ug/l and 0.005 to 0.09 ug/l in streams and lakes, respectively(1). The mean concn of eptam in the Yakima River Basin(WA) collected in Sept 1988 ranged from 1-2 ng/l(2). The median concn of eptam in streams draining agricultural and urban areas in Colorado were 0.029 and <0.01 ug/l, respectively, in 1993 to 1994(3). During 1990-91, eptam was detected in Maskenthine Lake and Willow Lake in northeastern Nebraska at concns of 0.06 ug/l and <0.05 ug/l, respectively(4).|GROUNDWATER: The majority (more than 90%) of eptam concns in ground water were reported to be zero or less than the detection limit (generally < 0.05 ug/l)(1). With the exception of three data values, the maximum eptam concn reported were 0.33 ug/l, 0.45 ug/l (<2% of the sites had detections), and 0.50 ug/l, respectively(1). Of the three samples where higher groundwater concns were noted, the first (2.7 ug/l) represents ground water at a mixer-loader site(1). The occurrence and maximum concn of eptam in shallow groundwater in the United States collected as part of the National Water-Quality Assessment (NAWQA) completed during 1993- 95, was 1.5% of all sites (N=1034) and 0.45 ug/l, respectively(2).|GROUNDWATER: Eptam was detected in groundwater at 53 of 4458 stations in the United States at an ave concn of 0.03 ug/l(1). Eptam was detected at a maximum concn of 2.9 ug/l in groundwater from WI; it was qualitatively detected in groundwater from MN(2).|RAIN/SNOW: Eptam was detected in 1985 at a concn less than 0.1 ug/l in 1 of 14 rain samples taken in West Lafayette, IN(1). Eptam was quantified in 5 of 318 Iowa rain samples at an ave concn of 1.07 ug/l during November, 1987 thru September, 1990(2).

NIOSH (NOHS survey 1974) has statistically estimated that 684 workers are potentially exposed to eptam in the US(1). The NOHS Survey does not include farm workers. Occupational exposure to eptam may occur through inhalation and dermal contact with this compound at workplaces where eptam is produced or used(SRC). In formulating plants, exposure to pesticides, such as eptam, may be from spillage(2). Furthermore, there is a high potential for exposure at mixing and bagging stations(2) and in pesticide storage areas which contain contaminated air(3). Eptam is applied to several crops via ground sprayers, cultivation equipment, soil injection and irrigation(4). Crop workers may be exposed during application(5); they may also be exposed from contact with treated foliage or to pesticide or pesticide-contaminated material made airborne through agitation of foliage during work activity(2). Monitoring data indicate that the general population may be exposed to eptam via inhalation of ambient air contaminated with this compound(SRC).

ROOT ABSORPTION OF EPTC WAS REPORTED ... IN OAT ... & IN ALFALFA. THE ABSORBED EPTC WAS READILY MOVED UPWARD TO THE FOLIAGE. THIS CHEMICAL IS ALSO ABSORBED BY THE COLEOPTILES & CAN BE TRANSLOCATED DOWNWARD TO THE ROOTS. ... THE RADIOSULFURFROM LABELED EPTC ACCUMULATES IN GROWING STEM & ROOT TIPS AFTER THE APPLICATION TO THE LEAVES. WHEN THE APPLICATION WAS MADE TO THE ROOTS, THE DISTRIBUTION WAS MORE UNIFORM.|... SEEDS OF KIDNEY BEAN, PEA, CORN, & OAT /WERE COVERED/ WITH DRY SOILS CONTAINING VARIOUS LEVELS OF (35)S EPTC, RANGING FROM 10 TO 100 PPM ... . NO SIGNIFICANT AMT OF RADIOACTIVITY WAS FOUND IN THE SEEDS AFTER 6 DAYS ... . A SIGNIFICANT AMT OF RADIOACTIVITY WAS TAKEN UP WHEN THE GERMINATING SEEDS /KIDNEY BEAN, PEA, CORN, & OAT/ WERE COVERED WITH WET SOIL CONTAINING (35)S EPTC. EPTC WAS ALSO TAKEN UP BY SEEDS THAT WERE GERMINATED BETWEEN 2 SHEETS OF FILTER PAPER MOISTENED WITH AN EPTC SOLN.|... VAPORS MAY BE ABSORBED BY FOLIAGE.|... AFTER A 0.6 MG DOSE /EPTC, ORAL, TO RATS/ 8% WAS EXCRETED IN THE URINE, 4% IN THE FECES, & 85% IN THE EXPIRED AIR, WHEREAS AFTER A DOSE OF 100.6 MG, 36, 11, & 38% WERE EXCRETED BY THESE ROUTES RESPECTIVELY. THE LARGER DOSE WAS ALSO EXCRETED MORE SLOWLY.|INCR THE DOSE OF EPTC /IN RATS/ FROM 0.63 TO 103 MG PER RAT LED TO A ... CORRESPONDING INCR IN URINARY EXCRETION OF RADIOACTIVITY. ... THE TIME FOR COMPLETE URINARY ELIMINATION OF RADIOACTIVITY WAS LIKEWISE EXTENDED /TO APPROX 35 HR FOR HIGHER DOSE/.

... THE RATE OF (35)S EPTC DEGRADATION IN GERMINATING SEEDS /WAS REPORTED/. DATA ... SHOW A GREATER DEGRADATION ... IN SEEDS OF THOSE SPECIES WHICH ARE RESISTANT TO THIS HERBICIDE THAN IN SUSCEPTIBLE SPECIES. THE RADIOSULFUR ... WAS INCORPORATED INTO CYSTEIC ACID, CYSTINE, METHIONINE, METHIONINE SULFONE & 2 UNIDENTIFIED COMPD.|COMPLETE OXIDATION OF THE ETHYL MOIETY OF THE EPTC MOLECULE TO CO2 BY RATS WAS REPORTED ... . INCREASING THE DOSE OF EPTC ... LED TO A DECR IN (14)CO2 OUTPUT ... . SIX MAJOR LABELED METABOLITES WERE FOUND ... AND THE RELATIVE AMOUNT OF 3 METABOLITES CHANGED WITH DOSE. ONE OF THE MAJOR METABOLITES WAS ... UREA, & 3 OTHERS, WHICH ACCOUNTED FOR 50-70% OF THE TOTAL RADIOACTIVITY IN THE URINE, WERE CONJUGATES OF EPTC OR EPTC-LIKE CMPD.|THIOCARBAMATE HERBICIDES ALSO REACT WITH GLUTATHIONE AFTER OXIDATIVE ACTIVATION. EG, EPTAM & ITS S-OXIDE LOWER HEPATIC GLUTATHIONE WHEN GIVEN TO MICE AND ARE EXCRETED AS A MERCAPTURIC ACID FROM RATS.|THE MAIN SOL METABOLITE WAS CARBAMOYLATED GLUTATHIONE. EPTC-SULFONE REACTED WITH GSH. EPTC WAS PARTIALLY OXIDIZED TO EPTC-SULFOXIDE IN IN VITRO ASSAYS USING 5 DAY OLD SEEDLINGS.|For more Metabolism/Metabolites (Complete) data for EPTAM (9 total), please visit the HSDB record page.

SYMPTOMS: Symptoms of exposure to this compound may include headache, giddiness, nervousness, blurred vision, weakness, nausea, cramps, diarrhea, sweating, miosis, tearing, salivation, vomiting and cyanosis. (NTP, 1992)|Teratogens

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop. SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. IMMEDIATELY call a hospital or poison control center even if no symptoms (such as redness or irritation) develop. IMMEDIATELY transport the victim to a hospital for treatment after washing the affected areas. INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. IMMEDIATELY call a physician and be prepared to transport the victim to a hospital even if no symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing. INGESTION: DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, administer a slurry of activated charcoal in water and simultaneously call a hospital or poison control center. IMMEDIATELY transport the victim to a hospital. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital. (NTP, 1992)

Fresh air, rest. Refer for medical attention.

Remove contaminated clothes. Rinse and then wash skin with water and soap.

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

Eptam

The substance can be absorbed into the body by inhalation, through the skin and by ingestion.

Dizziness. Headache. Nausea.

Redness.

Redness.

HERBICIDE, OF WHICH APPROXIMATELY 59% IS USED ON CORN, 31% ON VEGETABLES, 10% ON SUGAR BEETS (1975)|(1975) 2.91X10+9 GRAMS (CONSUMPTION)|Based on available pesticide survey usage information for the years of 1987 through 1996, an annual estimate of EPTC total domestic usage averaged approximately 20 million pounds for almost 6 million acres treated. Most of the usage is in CA, MI, OR, PA, ND, MN, AZ, SC, NC, AR, MT, IL, NE, LA, TX, KY, TN, AND CO.

USEPA/OPP Pesticide Code 041401; Trade Names: EPTAM; Eradicane.|Emulsifiable concentrate, granules

Carbamothioic acid, N,N-dipropyl-, S-ethyl ester: ACTIVE|EPTC is sometimes supplied in a mixture with N,N-diallyl-2,2-dichloroacetamide, which is supposed to be less toxic to maize.|Applied pre-planting with soil incorporation. Combinations with the safener dichlormid are used for herbicidal control in maize.

TLC DETECTION OF HERBICIDAL THIOCARBAMATES AND THEIR SULFOXIDE AND SULFONE METABOLITES|MULTIRESIDUE METHOD FOR DETERMINATION OF THIOCARBAMATE HERBICIDES IN DEEP FROZEN VEGETABLES USING TLC FOR DETECTION.|Product analysis by GLC; residues determined by GLC; in drinking water, by GC/FID.

Agrochemicals -> Herbicides|Health Hazards -> Teratogens|HERBICIDES