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Propionamide

Propionamide structure

CAS No:
79-05-0
Formula:
C3H7NO
Chemical Name:
Propionamide
Synonyms:
Propanamide;Propionamide;Propionic acid amide;Propionic amide;Propionimidic acid;Propanimidic acid;Propylamide;NSC 38708
Categories:
Organic Chemistry > Amides

Description

white to slightly yellow crystalline powder

Propionamide is a monocarboxylic acid amide obtained by the formal condensation of propionic acid with ammonia. It is a monocarboxylic acid amide and a primary fatty amide. It derives from a propionic acid.

Propionamide Basic Attributes

Molecular Weight：

73.09

Exact Mass：

73.09

EC Number：

201-172-1

UNII：

QK07G0HP47

NSC Number：

38708

DSSTox ID：

DTXSID3058820

HScode：

29241900

Characteristics

PSA：

43.1

XLogP3：

-0.7

Appearance：

White to slightly yellow Crystalline Powder

Density：

1.010 g/cm³ @ Temp: 20 °C

Melting Point：

81.3 °C

Boiling Point：

213 °C

Flash Point：

213°C

Refractive Index：

1.431

Water Solubility：

SOLUBLE

Storage Conditions：

Store below +30°C.

Vapor Pressure：

0.04 mmHg

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

hazard class code：

22-36/37/38

safety instructions：

24/25-36/37/39-26-37/39

RTECS Number：

UE2975000

Marks：

Precautionary statement(s)：

P264, P270, P301+P312, P330, P501

Hazard Statements：

H302

GHS Classification：

|Warning|H302 (90.91%): Harmful if swallowed [Warning Acute toxicity, oral]|P264, P270, P301+P312, P330, and P501|Aggregated GHS information provided by 44 companies from 2 notifications to the ECHA C&L Inventory.

Drug Information

MeSH Entry Terms：

propionamide

Propionamide Use and Manufacturing

Methods of Manufacturing

Derived from the reaction of propionic acid and ammonia. Ammonia gas is introduced into the reactor with n-propionic acid. When the temperature rises to about 140°C, all propionic acid will generate ammonium propionate. Stop the ammonia flow, increase the temperature for dehydration, and keep it at 210-220°C for 1-2h. Dehydrated completely. The crystals are cooled, filtered to obtain the crude product, and then recrystallized with ethanol to obtain the finished product.

Uses

Used in the synthesis of medicin

Manufacturing Info：

Propanamide: ACTIVE

Computed Properties

Molecular Weight:73.09
XLogP3:-0.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:73.052763847
Monoisotopic Mass:73.052763847
Topological Polar Surface Area:43.1
Heavy Atom Count:5
Complexity:42.2
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Material

Ethyl propionate

1-Propanol

Acrylamide

Downstream Products

Taurine

Ethyl ketone

Recommended Suppliers of Propionamide

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Propionamide

CAS No.: 79-05-0

Content: 99.00%

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