Ethyl ketone

86.13

86.13

635749

202-490-3

9SLZ98M9NK

0874

8653

1156

DTXSID6021820

Colorless, mobile liquid

2914190090

17.1

0.99 (estimated)

Clear colorless Liquid

0.816 g/cm³ @ Temp: 19 °C

-39 °C

101.9 °C

55 °F

1.383

H2O: 50 g/L (20 ºC)

Flammables area

20 mm Hg ( 28 °C)

3 (vs air)

Oral-Rat LD50: 2140 mg/kg

Inflammable in case of open flame, high temperature, oxidant; burning produces irritating smoke

1.6-7.7%(V)

Acetone odor

2.00e-12 cm3/molecule*sec

5.00e-05 atm-m3/mole|Henry's Law constant = 5.0X10-5 atm-cu m/mol at 25 °C

Heat capacity: 2.216 J/g-K|Enthalpy of formation: -296.5 kJ/mol (liquid); -257.9 kJ/mol (gas)|Hydroxyl radical reaction rate constant = 2.00X10-12 cu cm/molec-sec at 25 °C

Highly flammable. Slightly soluble in water

Ketones

Highly Flammable

DIETHYL KETONE is incompatible with the following: Strong oxidizers, alkalis, mineral acids, (hydrogen peroxide + nitric acid) (NIOSH, 2016).

842 °F (USCG, 1999)|842 °F (450 °C)|452 °C

3100.2 kJ/mole at 25 °C /liquid/

9.32 eV

Lower flammable limit: 1.6% by volume; Upper flammable limit: 6.4% by volume|Class IB Flammable Liquid: Fl.P. below 73°F and BP at or above 100°F.

The vapour is heavier than air and may travel along the ground; distant ignition possible. The vapour mixes well with air, explosive mixtures are easily formed.

38.52 kJ/mole at 25 °C

Critical temperature: 561.46 K; critical pressure: 3.729 MPa

II

3

UN 1156 3/PG 2

1

11-37-66-67

9-16-25-33

SA8050000

F,Xi

Treasury is ventilated, low temperature and dry; stored separately from oxidant

Explosive when mixed with air

Stable. Highly flammable. Readily forms explosive mixtures with air. Incompatible with strong bases, reducing agents, strong oxidizing agents.

P210-P305 + P351 + P338-P370 + P378-P403 + P235

H225-H319-H335-H336

SRP: The most favorable course of action is to use an alternative chemical product with less inherent propensity for occupational exposure or environmental contamination. Recycle any unused portion of the material for its approved use or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material's impact on air quality; potential migration in soil or water; effects on animal, aquatic, and plant life; and conformance with environmental and public health regulations.|Incineration /SRP: with effective emission controls/

Violent reaction with oxidizers, causing fire and explosion hazard. Forms explosive mixture with air. Incompatible with strong acids, aliphatic amines. Attacks many plastics, rubber and coatings. May accumulate static electrical charges, and may cause ignition of its vapors.|... can react vigorously with oxidizing materials. ... Reacts with hydrogen peroxide + nitric acid to form a shock- and heat-sensitive explosive peroxide.|Unless the temp and concn of reagents were carefully controlled, mixtures of hydrogen peroxide, nitric acid and acetone overheated and exploded violently. Under controlled conditions, the explosive dimeric or trimeric acetone peroxides were produced. 2-Butanone and 3-pentanone gave shock and heat sensitive peroxides.|Strong oxidizers, alkalis, mineral acids (hydrogen peroxide + mineral acids).

European Chemicals Bureau; IUCLID Dataset, 3-Pentanone (CAS # 99-22-0) Available from the Database Query page at: http://ecb.jrc.it/esis/esis.php as of November 16, 2007

UN 1156

P210; P305 + P351 + P338; P370 + P378; P403 + P235

Excerpt from ERG Guide 127 [Flammable Liquids (Water-Miscible)]: HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Those substances designated with a (P) may polymerize explosively when heated or involved in a fire. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water. (ERG, 2016)|Highly flammable. Vapour/air mixtures are explosive.|Flammable - 3rd degree

|Danger|H225: Highly Flammable liquid and vapor [Danger Flammable liquids]|P210, P233, P240, P241, P242, P243, P261, P271, P280, P303+P361+P353, P304+P340, P312, P370+P378, P403+P233, P403+P235, P405, and P501|H225 (100%): Highly Flammable liquid and vapor [Danger Flammable liquids]|Aggregated GHS information provided by 1850 companies from 22 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.|P210, P233, P240, P241, P242, P243, P261, P264, P271, P280, P303+P361+P353, P304+P340, P305+P351+P338, P312, P337+P313, P370+P378, P403+P233, P403+P235, P405, and P501|P210, P233, P240, P241, P242, P243, P260, P261, P264, P270, P271, P280, P301+P310, P303+P361+P353, P304+P340, P305+P351+P338, P307+P311, P312, P321, P331, P332+P313, P337+P313, P370+P378, P403+P233, P403+P235, P405, and P501

Excerpt from ERG Guide 127 [Flammable Liquids (Water-Miscible)]: As an immediate precautionary measure, isolate spill or leak area for at least 50 meters (150 feet) in all directions. LARGE SPILL: Consider initial downwind evacuation for at least 300 meters (1000 feet). FIRE: If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2016)

Excerpt from ERG Guide 127 [Flammable Liquids (Water-Miscible)]: ELIMINATE all ignition sources (no smoking, flares, sparks or flames in immediate area). All equipment used when handling the product must be grounded. Do not touch or walk through spilled material. Stop leak if you can do it without risk. Prevent entry into waterways, sewers, basements or confined areas. A vapor-suppressing foam may be used to reduce vapors. Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers. Use clean, non-sparking tools to collect absorbed material. LARGE SPILL: Dike far ahead of liquid spill for later disposal. Water spray may reduce vapor, but may not prevent ignition in closed spaces. (ERG, 2016)

Skin: No recommendation is made specifying the need for personal protective equipment for the body. Eyes: Wear appropriate eye protection to prevent eye contact. Wash skin: The worker should wash daily at the end of each work shift. Remove: Work clothing that becomes wet should be immediately removed due to its flammability hazard(i.e. for liquids with flash point Change: No recommendation is made specifying the need for the worker to change clothing after the work shift. (NIOSH, 2016)|/Wear/ safety spectacles, protective gloves. /Use/ ventilation.|Wear appropriate eye protection to prevent eye contact.|(See protection codes)

Dangerous fire hazard when exposed to heat or flame ...

Lower: 1.6% /by volume/|Explosive limits , vol% in air: 1.6-3

In case of fire: keep drums, etc., cool by spraying with water. AFFF, alcohol-resistant foam, powder, carbon dioxide.|WATER MAY BE INEFFECTIVE FIGHTING FIRES WITH LOW FLASH POINT. ALCOHOL FOAM.|If material on fire or involved in fire: Do not extinquish fire unless flow can be stopped. Use water in flooding quantities as fog. Solid streams of water may spread fire. Cool all affected containers with flooding quantities of water. Apply water from as far a distance as possible. Use "alcohol" foam, dry chemical or carbon dioxide.

Evacuate and restrict persons not wearing protective equipment from area of spill or leak until cleanup is complete. Remove all ignition sources. Establish forced ventilation to keep levels below explosive limit. Absorb liquids in vermiculite, dry sand, earth, peat, carbon, or similar material and deposit in sealed containers. Keep this chemical out of a comfined space ... because of the possibility of an explosion ... It may be necessary to contain and dispose of this chemical as a hazardous waste. If material or contaminated runoff enters waterways, notify downstream users of potentially contaminated waters. Contact your Department of Environmental Protection or your regional office of the federal EPA for specific recommendations. If employees are required to clean up spills, they must be properly trained and equipped. OSHA 1910.120(q) may be applicable.

Do not eat, drink, or smoke during work.|If material not on fire and not involved in fire: Keep sparks, flames, and other sources of ignition away. Keep material out of water sources and sewers. Build dikes to contain flow as necessary. Attempt to stop leak if without undue personnel hazard. Use water spray to disperse vapors and dilute standing pools of liquid.|Personnel protection: Avoid breathing vapors. Keep upwind. ... Do not handle broken packages unless wearing appropriate personal protective equipment. Wash away any material which may have contacted the body with copious amounts of water or soap and water.|The worker should wash daily at the end of each work shift, and prior to eating, drinking, smoking, etc.|For more Preventive Measures (Complete) data for 3-PENTANONE (8 total), please visit the HSDB record page.

/GUIDE 127: FLAMMABLE LIQUIDS (Polar/Water-Miscible)/ Fire or Explosion: HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Those substances designated with a (P) may polymerize explosively when heated or involved in a fire. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.|/GUIDE 127: FLAMMABLE LIQUIDS (Polar/Water-Miscible)/ Health: Inhalation or contact with material may irritate or burn skin and eyes. Fire may produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control may cause pollution.|/GUIDE 127: FLAMMABLE LIQUIDS (Polar/Water-Miscible)/ Public Safety: CALL Emergency Response Telephone Number on Shipping Paper first. If Shipping Paper not available or no answer, refer to appropriate telephone number listed on the inside back cover. As an immediate precautionary measure, isolate spill or leak area for at least 50 meters (150 feet) in all directions. Keep unauthorized personnel away. Stay upwind. Keep out of low areas. Ventilate closed spaces before entering.|/GUIDE 127: FLAMMABLE LIQUIDS (Polar/Water-Miscible)/ Protective Clothing: Wear positive pressure self-contained breathing apparatus (SCBA). Structural firefighters' protective clothing will only provide limited protection.|For more DOT Emergency Guidelines (Complete) data for 3-PENTANONE (8 total), please visit the HSDB record page.

No person may /transport,/ offer or accept a hazardous material for transportation in commerce unless that person is registered in conformance ... and the hazardous material is properly classed, described, packaged, marked, labeled, and in condition for shipment as required or authorized by ... /the hazardous materials regulations (49 CFR 171-177)./|The International Air Transport Association (IATA) Dangerous Goods Regulations are published by the IATA Dangerous Goods Board pursuant to IATA Resolutions 618 and 619 and constitute a manual of industry carrier regulations to be followed by all IATA Member airlines when transporting hazardous materials.|The International Maritime Dangerous Goods Code lays down basic principles for transporting hazardous chemicals. Detailed recommendations for individual substances and a number of recommendations for good practice are included in the classes dealing with such substances. A general index of technical names has also been compiled. This index should always be consulted when attempting to locate the appropriate procedures to be used when shipping any substance or article.

The substance irritates the eyes, the skin and the respiratory tract.

Vacated 1989 OSHA PEL TWA 200 ppm (705 mg/cu m) is still enforced in some states.

Recommended Exposure Limit: 10 Hr Time-Weighted Avg: 200 ppm (705 mg/cu m).

Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Ventilation. Collect leaking and spilled liquid in sealable metal (mild steel) containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. Do NOT wash away into sewer.

Fireproof. Separated from oxidants.

A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20 °C.

The substance is irritating to the eyes, skin and respiratory tract.

The substance defats the skin, which may cause dryness or cracking.

NO open flames, NO sparks and NO smoking. Closed system, ventilation, explosion-proof electrical equipment and lighting. Do NOT use compressed air for filling, discharging, or handling.

Use ventilation.

Protective gloves.

Wear safety spectacles.

| 1 - Materials that, under emergency conditions, can cause significant irritation.| 3 - Liquids and solids that can be ignited under almost all ambient temperature conditions. Materials produce hazardous atmospheres with air under almost all ambient temperatures or, though unaffected by ambient temperatures, are readily ignited under almost all conditions.| 0 - Materials that in themselves are normally stable, even under fire conditions.

The major hazards encountered in the use and handling of 3-pentanone stem from its toxicologic properties and flammability. Toxic by all routes (ie, inhalation, ingestion, and dermal contact), exposure to this colorless acetone-smelling liquid may occur from its use in organic syntheses. Effects from exposure may include contact burns to the skin and eyes, tachycardia, nausea, shortness of breath, headache, dizziness, fainting, coma and death. Both the OSHA PEL and the ACGIH TLV have been set at a TWA of 200 ppm. In activities or situations where over-exposure may occur, wear a self-contained breathing apparatus and chemical protective clothing. If contact should occur, immediately flush affected skin or eyes with running water for at least 15 minutes. Remove contaminated clothing and shoes at the site. 3-Pentanone may be easily ignited by heat, sparks, or flame (Flash point: 13 °C, open cup). Its heavier than air vapor and may travel to a source of ignition and flash back, or result in a build-up of explosive concentrations in enclosed spaces such as sewers. Also, containers may explode in the heat of a fire. 3-Pentanone fires may produce poisonous gases. Therefore, if a tank car or truck is involved in the fire, isolate the area for 1/2 mile in all directions. 3-Pentanone fires may be extinguished with dry chemical, CO2, Halon, standard or alcohol foam, and water spray or fog (solid streams of water may spread the fire). Fight the fire from as far a distance as possible and dike the fire control water. 3-Pentanone should be stored away from sources of ignition and oxidizing materials. 3-Pentanone may be shipped via air, rail, road, and water. Small spills of 3-pentanone may be taken up with sand or other noncombustible absorbent and placed into containers for later disposal. Before implementing land disposal of waste 3-pentanone, consult with environmental regulatory agencies for guidance.

In a comprehensive survey of wastewater from 4000 industrial and publicly owned treatment works (POTWs) sponsored by the Effluent Guidelines Division of the USEPA, diethyl ketone was identified in discharges of the following industrial category (positive occurrences; median concn in ppb): nonferrous metals (1;26.7), ore mining (3;2.1), organics and plastics (1;47.3), plastics and synthetics (1; 2491.1), pulp and paper (1; 27.5)(1). The highest effluent concn was 2491.1 ppb in the plastics and synthetics industry(1). Diethyl ketone was identified, not quantified, in effluent from an advanced wastewater treatment plant in Lake Tahoe, CA(2). Diethyl ketone has been identified in automobile exhaust(3).

SEDIMENT: Diethyl ketone has been identified, not quantified, in sediment beneath a reed bed in Lake Constance, Switzerland(1). The maximum concns were found adjacent to zones of former reed growth, suggesting that diethyl ketone was formed by microbial processes(SRC). Diethyl ketone was detected at concns of 0-0.46 ppb and 0-0.75 ppb in 2 of 3 sediment cores at 3 shallow sites from Walvis Bay off the arid coast of Southwest Africa(2).

URBAN/SUBURBAN: Diethyl ketone was detected at 0.14 ppb in air samples taken in Leipzig, Germany from March 1993 to November 1995(1).|RURAL/REMOTE: Diethyl ketone was identified, not quantified, in 1 of 7 air samples from the Kanawha Valley in WV (St Albans)(1). Diethyl ketone was identified, not quantified, in a forest in West Germany(2). Diethyl ketone was detected at 0.11 ppb in air samples from Melpitz, Germany from March 1993 to November 1995(3).|SOURCE DOMINATED: Diethyl ketone was detected at a concn of 0.57 ppb near an oil shale facility, however it was not detected in nearby rural and urban areas(1). Diethyl ketone was detected at a concn 2 ppb near a chemical manufacturing site(2).|INDOOR AIR: In a 1978-1990 international survey of 1,128 dwellings, 112 offices, 8 hospitals and 30 schools, diethyl ketone was detected in 1 school(1).

Diethyl ketone has been identified in cigarette smoke(1).

moderately toxic

LD50 Mouse iv 513 mg/kg bw|LD50 Mouse ip 810 mg/kg bw|LD50 Rabbit dermal >5000 mg/kg|LD50 Rabbit dermal 16200 mg/kg|LD50 Rat oral 2.14 g/kg

/AQUATIC SPECIES/ Affected fish (fathead minnow) /exposed to mean concentrations of 259-2300 mg/L/96 hr/ stopped schooling, came to water surface with pronounced operculation, then lost equilibrium prior to death.|/OTHER TERRESTRIAL SPECIES/ Ketones, incl 3-pentanone, were tested for their ability to release alarm pheromones in ants. The most active cmpd were of a size & geometry similar to 4-methyl-3-heptanone.

Diethyl ketone is a volatile emitted from many plants and fruits including European birch, European larch, European fir, Scots pine, Siberian pine, evergreen cyprus and northern white cedar(1). Diethyl ketone is emitted from blooming rape(2) and is also found in kiwi(3,4) and nectarines(5).

Diethyl ketone's production and use as a solvent for paints and as a starting material for organic syntheses(1) may result in its release to the environment through various waste streams(SRC).

TERRESTRIAL FATE: Based on a classification scheme(1), an estimated Koc value of 82(SRC), determined from a log Kow of 0.99(2) and a regression-derived equation(3), indicates that diethyl ketone is expected to have high mobility in soil(SRC). Volatilization of diethyl ketone from moist soil surfaces is expected to be an important fate process(SRC) given a Henry's Law constant of 5.0X10-5 atm-cu m/mole(4). Diethyl ketone is expected to volatilize from dry soil surfaces(SRC) based upon a vapor pressure of 37.7 mm Hg(5). Using an acclimated sewage inocula diethyl ketone reached 50.8%(6) and 38%(7) of the theoretical BOD over a 10 day incubation period, suggesting that biodegradation may be an important environmental fate process in soil(SRC).|AQUATIC FATE: Based on a classification scheme(1), an estimated Koc value of 82(SRC), determined from a log Kow of 0.99(2) and a regression-derived equation(3), indicates that diethyl ketone is not expected to adsorb to suspended solids and sediment(SRC). Volatilization from water surfaces is expected(3) based upon a Henry's Law constant of 5.0X10-5 atm-cu m/mole(4). Using this Henry's Law constant and an estimation method(3), volatilization half-lives for a model river and model lake are 19 hours and 8.6 days, respectively(SRC). According to a classification scheme(5), an estimated BCF of 3(SRC), from its log Kow(2) and a regression-derived equation(6), suggests the potential for bioconcentration in aquatic organisms is low(SRC). Using an acclimated sewage inocula diethyl ketone reached 50.8%(7) and 38%(8) of the theoretical BOD over a 10 day incubation period, suggesting that biodegradation may be an important environmental fate process in water(SRC).|ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), diethyl ketone, which has a vapor pressure of 37.7 mm Hg at 25 °C(2), is expected to exist solely as a vapor in the ambient atmosphere. Vapor-phase diethyl ketone is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be 8 days(SRC), calculated from its rate constant of 2.0X10-12 cu cm/molecule-sec at 25 °C(3). Diethyl ketone contains chromophores that absorb at wavelengths >290 nm and therefore may be susceptible to direct photolysis by sunlight(4).

The rate constant for the vapor-phase reaction of diethyl ketone with photochemically-produced hydroxyl radicals has been measured as 2.0X10-12 cu cm/molecule-sec at 25 °C(1). This corresponds to an atmospheric half-life of about 8 days at an atmospheric concentration of 5X10+5 hydroxyl radicals per cu cm(1). Diethyl ketone is not expected to undergo hydrolysis in the environment due to the lack of functional groups that hydrolyze under environmental conditions(2). Diethyl ketone contains chromophores that absorb at wavelengths >290 nm and therefore may be susceptible to direct photolysis by sunlight(2).

An estimated BCF of 3 was calculated in fish for diethyl ketone(SRC), using a log Kow of 0.99(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC).

The Koc of diethyl ketone is estimated as 82(SRC), using a log Kow of 0.99(1) and a regression-derived equation(2). According to a classification scheme(3), this estimated Koc value suggests that diethyl ketone is expected to have high mobility in soil.

The Henry's Law constant for diethyl ketone is 5.0X10-5 atm-cu m/mole(1). This Henry's Law constant indicates that diethyl ketone is expected to volatilize from water surfaces(2). Based on this Henry's Law constant, the volatilization half-life from a model river (1 m deep, flowing 1 m/sec, wind velocity of 3 m/sec)(2) is estimated as 19 hours(SRC). The volatilization half-life from a model lake (1 m deep, flowing 0.05 m/sec, wind velocity of 0.5 m/sec)(2) is estimated as 8.6 days(SRC). diethyl ketone's Henry's Law constant indicates that volatilization from moist soil surfaces may occur(SRC). Diethyl ketone is expected to volatilize from dry soil surfaces(SRC) based upon a vapor pressure of 37.7 mm Hg(3).

DRINKING WATER: Diethyl ketone was identified, not quantified, in 6 of 14 drinking water supplies in England(1).|GROUNDWATER: Diethyl ketone was not found in groundwater at a coal gasification site in Hanna, WY although it is found in process water(1).

Diethyl ketone was identified, not quantified, in the volatiles of raw chicken breast(1), mutton, chicken and pork(2), kiwi(3,4), roasted earth almonds (Cyperus esculentus L.)(5) and nectarines(6).

Occupational exposure to diethyl ketone may occur through inhalation and dermal contact with this compound at workplaces where diethyl ketone is produced or used. Monitoring data indicate that the general population may be exposed to diethyl ketone via inhalation of ambient air, ingestion of food and drinking water, and dermal contact with products containing diethyl ketone. (SRC)

Liquid causes eye burn. Vapor irritates eyes, nose and throat; can cause headache, dizziness, nausea, weakness, and loss of consciousness. (USCG, 1999)

Eye: If this chemical contacts the eyes, immediately wash the eyes with large amounts of water, occasionally lifting the lower and upper lids. Get medical attention immediately. Contact lenses should not be worn when working with this chemical. Skin: If this chemical contacts the skin, wash the contaminated skin with soap and water. Breathing: If a person breathes large amounts of this chemical, move the exposed person to fresh air at once. If breathing has stopped, perform mouth-to-mouth resuscitation. Keep the affected person warm and at rest. Get medical attention as soon as possible. Swallow: If this chemical has been swallowed, get medical attention immediately. (NIOSH, 2016)|(See procedures)

Fresh air, rest. Refer for medical attention.

Remove contaminated clothes. Rinse skin with plenty of water or shower.

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

INHALATION. Symptoms: Cough. Shortness of breath. First aid: Fresh air, rest. Refer for medical attention. SKIN: Symptoms: Dry skin. Redness. First aid: Remove contaminated clothes. Rinse skin with plenty of water or shower. EYES: Symptoms: Redness. First aid: First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor. INGESTION: First aid: Rinse mouth.|Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand-valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR as necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. /Ketones and related compounds/|Basic treatment: Establish a patent airway (oropharyngeal or nasopharyngeal airway, if needed). Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary ... . For contamination, flush eyes immediately with water. Irrigate each eye continuously with 0.9% saline (NS) during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 ml/kg up to 200 ml of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool. Administer activated charcoal ... . /Ketones and related compounds/|Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious, has severe pulmonary edema, or is in severe respiratory distress. Positive-pressure ventilation techniques with a bag valve mask device may be beneficial. Consider drug therapy for pulmonary edema ... . Consider administering a beta agonist such as albuterol for severe bronchospasm ... . Monitor cardiac rhythm and treat arrhythmias if necessary ... . Start IV administration of D5W /SRP: "To keep open", minimal flow rate/. Use 0.9% saline (NS) or lactated Ringer's (LR) if signs of hypovolemia are present. For hypotension with signs of hypovolemia, administer fluid cautiously. Watch for signs of fluid overload ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Ketones and related compounds/

3-pentanone

The substance can be absorbed into the body by inhalation of its vapour.|inhalation, ingestion, skin and/or eye contact

irritation eyes, skin, mucous membrane, respiratory system; cough, sneezing

Cough. Shortness of breath.

Dry skin. Redness.

Redness.

Eyes, skin, respiratory system

Grade: Technical

Pesticide, fertilizer, and other agricultural chemical manufacturing|3-Pentanone: ACTIVE|METHOD OF PURIFICATION: RECTIFICATION

GAS CHROMATOGRAPHIC SEPARATION OF 22 CARBONYL COMPOUNDS AS THEIR 2,4-DINITROPHENYLHYDRAZONES WAS INVESTIGATED USING GLASS CAPILLARY COLUMNS. OPTIMUM CONDITIONS: STATIONARY PHASE SF-96; COLUMN SIZE 20 M X 0.25 MM ID; INJECTION & DETECTOR TEMP 280-290 °C; GAS FLOW-RATE HELIUM 1.0-1.2 ML/MIN. THE METHOD WAS APPLIED TO THE ANALYSIS OF ALIPHATIC CARBONYL CMPD IN CAR EXHAUST FUMES AND CIGARET SMOKE.|ACETIC ACID-SULFURIC ACID MIXTURE (1:1) WAS USED AS SOLVENT FOR DETERMINATION OF DIETHYL KETONE IN THE AIR @ 510-520 NM. DIETHYL KETONE WAS TRAPPED IN MIDGET IMPINGERS FILLED WITH ACETIC ACID, FOR DETECTION OF 2.5-19.8%.|Method: OSHA PV2136; Procedure: gas chromatography with flame ionization detector; Analyte: diethyl ketone; Matrix: air; Detection Limit: 32.6 pg/injection.

Food additives -> Flavoring Agents|Fatty Acyls [FA] -> Oxygenated hydrocarbons [FA12]|Fire Hazards -> Flammable - 3rd degree

Flavoring Agents