Chlorotrifluoroethylene

116.47

116.47

201-201-8

AF215GW34G

0685

1082

DTXSID3026485

Colorless gas

0

1.65 (est)

Trifluorochloroethylene is a colorless gas with a faint ethereal odor. It is shipped as a liquefied gas under its vapor pressure. It is very toxic by inhalation and is easily ignited. The vapors are heavier than air and a flame can flash back to the source of leak very easily. This leak can either be a liquid or vapor leak. The vapors can asphyxiate by the displacement of air. Contact with the liquid can cause frostbite. Under prolonged exposure to intense heat or fire the containers may violently rupture and rocket, or the material may polymerize with possible container rupture.

1.3 g/cm³

-158.2 °C

-27.9 °C

-28°C

1.38 (0ºC)

soluble in benzene, chloroform

Fireproof. Cool.

Vapour pressure, kPa at 25°C: 612

4.13 (vs air)

Inhalation-Rat LC50: 1000 PPM/ 4 hours; Oral-Mouse LD50: 268 mg/kg

Open flame is flammable; decomposes toxic fluoride and chloride gas in contact with water or heat

vol% in air: 240.3

Faint etheral odor

7.00e-12 cm3/molecule*sec

Henry's Law constant = 0.311 atm-cu m/mol at 25 °C (est)

Decomposes in water|FP: -157.5 °C|Hydroxyl radical reaction rate constant = 7.0X10-12 cu cm/molec-sec at 25 °C|Ozone reaction rate constant = 0.002X10-17 cu cm/molecule-sec at 25 °C (est)

Highly flammable.

Halogenated Organic Compounds

Highly Flammable

Halogenated aliphatic compounds, such as TRIFLUOROCHLOROETHYLENE, are moderately or very reactive. Halogenated organics generally become less reactive as more of their hydrogen atoms are replaced with halogen atoms. Low molecular weight haloalkanes are highly flammable and can react with some metals to form dangerous products. Materials in this group are incompatible with strong oxidizing and reducing agents. Also, they are incompatible with many amines; nitrides; azo/diazo compounds; alkali metals; strong oxidizers such as chlorine perchlorate, oxygen, bromine; and epoxides.

Chlorotrifluorethylene|C: Compounds that autopolymerize due to peroxide formation if inhibitors are depleated or not present|Kelly

Lower: 8.4% Upper: 38.7% by vol|Lower flame limit: 14.2%; Upper flame limit: 43.7%

The gas mixes well with air, explosive mixtures are easily formed.

83 BTU/LB= 46 CAL/G= 1.92X10+5 J/KG

CRITICAL PRESSURE: 592 PSIA= 40.2 ATM= 4.08 MN/SQ M; CRITICAL TEMP: 223.2 °F= 106.2 °C= 379.4 DEG K

2.3

UN 1082 2.3

3

12-20/22

16-38

KV0525000

F+,Xn,T,F

Warehouse ventilated, low temperature and dry; light loading and unloading

Flammable/Toxic

Steel cylinders can explode when exposed to heat or sunlight; highly toxic and combustible gases are released

Polymerizes easily.

P210, P260, P264, P270, P309+P311, P314, P377, P381, P403, P405, P410+P403, P501

H220

SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.

Violent reaction when mixed with (/bromine/ + /oxygen/) or (/chlorine trifluoride/ + water). Incompatible with 1,1-dichloroethylene; oxygen.|Explosive or similarly vigorous reactions between halogenated hydrocarbons, including chlorotrifluoroethylene, and other chemicals ...|Substance is unstable when mixed with oxygen or air, leading to peroxide formation.|Partial oxidation of a gasoline fraction in an autoclave under oxygen, initially at 22 bar and 100 °C, ran wild and exploded; several smaller reactions had proceeded uneventfully.|Interaction of the reactants (pre-mixed at -196 °C) during warming to -78 °C, then ambient temperature, exploded. Progressive addition of the alkene to the perchlorate at -78 was uneventful.

Clayton JW; Toxicology of the fluoro alkenes Review and research needs; Environ Health Perspect (21): 255 (1977). Review of the toxicology of fluoroalkenes.

Special Hazards of Combustion Products: Toxic hydrogen chloride and hydrogen fluoride gases are formed. Behavior in Fire: Vapor is heavier than air and may travel considerable distance to a source of ignition and flash back. Containers may explode in a fire. (USCG, 1999)|Flammable. Gas/air mixtures are explosive.|Flammable - 4th degree, Reactive - 3rd degree

|Danger|H220 (89.29%): Extremely flammable gas [Danger Flammable gases]|P210, P261, P264, P270, P271, P301+P310, P304+P340, P311, P321, P330, P377, P381, P403, P403+P233, P405, P410+P403, and P501|Aggregated GHS information provided by 140 companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.|H220: Extremely flammable gas [Danger Flammable gases]|P210, P260, P264, P270, P309+P311, P314, P377, P381, P403, P405, P410+P403, and P501

Excerpt from ERG Guide 119P [Gases - Toxic - Flammable]: As an immediate precautionary measure, isolate spill or leak area for at least 100 meters (330 feet) in all directions. SPILL: See ERG Table 1 - Initial Isolation and Protective Action Distances on the UN/NA 1082 datasheet. FIRE: If tank, rail car or tank truck is involved in a fire, ISOLATE for 1600 meters (1 mile) in all directions; also, consider initial evacuation for 1600 meters (1 mile) in all directions. (ERG, 2016)

Excerpt from ERG Guide 119P [Gases - Toxic - Flammable]: ELIMINATE all ignition sources (no smoking, flares, sparks or flames in immediate area). All equipment used when handling the product must be grounded. Fully encapsulating, vapor-protective clothing should be worn for spills and leaks with no fire. Do not touch or walk through spilled material. Stop leak if you can do it without risk. Do not direct water at spill or source of leak. Use water spray to reduce vapors or divert vapor cloud drift. Avoid allowing water runoff to contact spilled material. FOR CHLOROSILANES, use AFFF alcohol-resistant medium-expansion foam to reduce vapors. If possible, turn leaking containers so that gas escapes rather than liquid. Prevent entry into waterways, sewers, basements or confined areas. Isolate area until gas has dispersed. (ERG, 2016)

Self-contained breathing apparatus; goggles; rubber gloves. (USCG, 1999)|Wear appropriate chemical protective gloves and goggles. /Trifluorochloroethylene, stabilized/

Very dangerous fire hazard when exposed to heat, flames (sparks), or oxidizers.

Lower, 24%; Upper, 40.3%.|Explosive when under influence of a flame.|Explosive limits , vol% in air: 24-40.3

For fires involving flammable gases, the best procedure is to stop the flow of the gas before attempting extinguishment of the fire. To extinguish the fire while allowing continued flow of the gas is extremely dangerous; an explosive cloud of gas/air mixture may be created that, if ignited, may cause far more damage than the original fire. Extinguishing the flame using carbon dioxide or dry chemical may be desirable to allow immediate access to valves to shut off the flow of gas, but this must be done carefully. In many cases, it will be preferable to allow continued burning, while protecting exposures with water spray, until the flow of gas can be stopped.|If material on fire or involved in fire: Do not extinguish fire unless flow can be stopped. Use water in flooding quantities as fog. Cool all affected containers with flooding quantities of water. Apply water from as far a distance as possible. /Trifluorochloroethylene, stabilized/|Wear positive pressure self-contained breathing apparatus. /Trifluorochloroethylene, stabilized/|Evacuation: If fire becomes uncontrollable or container is exposed to direct flame - consider evacuation of one-half (1/2) mile radius. /Trifluorochloroethylene, stabilized/|Shut off supply ... extinguish with water spray, alcohol-resistant foam, dry powder, carbon dioxide.

Ventilation. Remove all ignition sources. Remove vapor with fine water spray. Personal protection: self-contained breathing apparatus.

If material not on fire and not involved in fire: Keep sparks, flames, and other sources of ignition away. Keep material out of water sources and sewers. Attempt to stop leak if without undue personnel hazard. Use water spray to knock-down vapors. /Trifluorochloroethylene, stabilized/|Personnel protection: Avoid breathing vapors. Keep upwind. ... Do not handle broken packages unless wearing appropriate personal protective equipment. Approach fire with caution. /Trifluorochloroethylene, stabilized/|Evacuation: If material leaking (not on fire) consider evacuation from downwind area based on amount of material spilled, location, and weather conditions. /Trifluorochloroethylene, stabilized/

If ... THERE IS NO FIRE, go directly to the Table of Initial Isolation and Protective Action Distances /(see table below)/ ... to obtain initial isolation and protective action distances. IF THERE IS A FIRE, or IF A FIRE IS INVOLVED, go directly to the appropriate guide /(see guide(s) below)/ and use the evacuation information shown under PUBLIC SAFETY. /Trifluorochloroethylene, stabilized/|/GUIDE 119P: GASES - TOXIC - FLAMMABLE/ Health: TOXIC; may be fatal if inhaled or absorbed through skin. Contact with gas or liquefied gas may cause burns, severe injury and/or frostbite. Fire will produce irritating, corrosive and/or toxic gases. Runoff from fire control may cause pollution. /Trifluorochloroethylene; Trifluorochloroethylene, stabilized/|/GUIDE 119P: GASES - TOXIC - FLAMMABLE/ Fire or Explosion: Flammable; may be ignited by heat, sparks or flames. May form explosive mixtures with air. Those substances designated with a "P" may polymerize explosively when heated or involved in a fire. Vapors from liquefied gas are initially heavier than air and spread along ground. Vapors may travel to source of ignition and flash back. Some of these materials may react violently with water. Cylinders exposed to fire may vent and release toxic and flammable gas through pressure relief devices. Containers may explode when heated. Ruptured cylinders may rocket. Runoff may create fire or explosion hazard. /Trifluorochloroethylene; Trifluorochloroethylene, stabilized/|/GUIDE 119P: GASES - TOXIC - FLAMMABLE/ Public Safety: CALL Emergency Response Telephone Number ... As an immediate precautionary measure, isolate spill or leak area for at least 100 meters (330 feet) in all directions. Keep unauthorized personnel away. Stay upwind. Many gases are heavier than air and will spread along ground and collect in low or confined areas (sewers, basements, tanks). Keep out of low areas. Ventilate closed spaces before entering. /Trifluorochloroethylene; Trifluorochloroethylene, stabilized/|For more DOT Emergency Guidelines (Complete) data for Chlorotrifluoroethylene (9 total), please visit the HSDB record page.

No person may /transport,/ offer or accept a hazardous material for transportation in commerce unless that person is registered in conformance ... and the hazardous material is properly classed, described, packaged, marked, labeled, and in condition for shipment as required or authorized by ... /the hazardous materials regulations (49 CFR 171-177)./|The International Air Transport Association (IATA) Dangerous Goods Regulations are published by the IATA Dangerous Goods Board pursuant to IATA Resolutions 618 and 619 and constitute a manual of industry carrier regulations to be followed by all IATA Member airlines when transporting hazardous materials.|The International Maritime Dangerous Goods Code lays down basic principles for transporting hazardous chemicals. Detailed recommendations for individual substances and a number of recommendations for good practice are included in the classes dealing with such substances. A general index of technical names has also been compiled. This index should always be consulted when attempting to locate the appropriate procedures to be used when shipping any substance or article.

Ventilation. Remove all ignition sources. Remove vapour with fine water spray. Personal protection: self-contained breathing apparatus.

Fireproof. Cool.

A harmful concentration of this gas in the air will be reached very quickly on loss of containment.

The liquid may cause frostbite. The substance may cause effects on the kidneys.

NO open flames, NO sparks and NO smoking. Closed system, ventilation, explosion-proof electrical equipment and lighting. Prevent build-up of electrostatic charges (e.g., by grounding).

Use ventilation, local exhaust or breathing protection.

Cold-insulating gloves.

Wear safety goggles.

| 3 - Materials that, under emergency conditions, can cause serious or permanent injury.| 4 - Materials that rapidly or completely vaporize at atmospheric pressure and normal ambient temperature or that are readily dispersed in air and burn readily.| 3 - Materials that in themselves are capable of detonation or explosive decomposition or explosive reaction but that require a strong initiating source or must be heated under confinement before initiation.

Chlorotrifluoroethylene was detected, not quantified in a groundwater sample near the Gloucester landfill, used for disposal of organic chemicals from the Government's laboratories in Ottawa, in Ontario Canada(1).

highly toxic

The effect of isoflurane on the anaerobic metabolism of halothane to chlorodifluoroethene (CDE) and chlorotrifluoroethane (CTE) was studied with microsomes of guinea pig liver. The Km values for chlorotrifluoroethane formation were 1204.74, 553.75, 521.14, 560.67, and 711.05 uM at 0 mM, 0.12 mM, 0.29 mM, 0.58 mM and 1.16 mM isoflurane, respectively. In contrast, the Vmax values for chlorodifluoroethene and chlorotrifluoethane formation at these isoflurane concentrations were not significantly different than in the control groups. The production of chlorodifluoroethene and chlorotrifluoroethane was significantly increased by isoflurane, at concentrations up to 0.58 mM.

LC50 Rat inhalation 1000 ppm/4 hr|LC50 Rat inhalation 5040 ppm/2 hr|LD50 Mouse oral 268 mg/kg|LD50 Mouse ip 175 mL/kg bw /SRP: 270 mg/kg/|For more Non-Human Toxicity Values (Complete) data for Chlorotrifluoroethylene (8 total), please visit the HSDB record page.

Chlorotrifluoroethylene's production and use as a chemical intermediate(1) may result in its release to the environment through various waste streams(SRC). The transformation of trichlorotriflurorethane (CFC-113) in the environment is believed to occur via reductive dechlorination to form 1,2-dichloro-1,2,2-trifluoroethane and then, through elimination, chlorotrifluoroethylene(2).|Chlorotrifluoroethylene was found to be a biodegradation product of trichlorotrifluoroethane in an investigation of natural attenuation potential of peat and sewage sludge from a Dutch halogen-contaminated industrial site(1). In groundwater studies of the Gloucester landfill project in Ontario, Canada, trichlorotrifluoroethylene is biotransformed via reductive dechlorination to form chlorotrifluoroethylene(2).

TERRESTRIAL FATE: Based on a classification scheme(1), an estimated Koc value of 95(SRC), determined from a structure estimation method(2), indicates that chlorotrifluoroethylene is expected to have high mobility in soil(SRC). Volatilization of chlorotrifluoroethylene from moist soil surfaces is expected to be an important fate process(SRC) given an estimated Henry's Law constant of 0.31 atm-cu m/mole(SRC), using a fragment constant estimation method(3). Chlorotrifluoroethylene is expected to volatilize from dry soil surfaces(SRC) based upon a vapor pressure of 4.59X10+3 mm Hg at 25 °C(4). Biodegradation data in soil were not available(SRC,2010).|AQUATIC FATE: Based on a classification scheme(1), an estimated Koc value of 95(SRC), determined from a structure estimation method(2), indicates that chlorotrifluoroethylene is not expected to adsorb to suspended solids and sediment(SRC). Volatilization from water surfaces is expected(3) based upon an estimated Henry's Law constant of 0.31 atm-cu m/mole(SRC), developed using a fragment constant estimation method(4). Using this Henry's Law constant and an estimation method(3), volatilization half-lives for a model river and model lake are 3 hours and 4 days, respectively(SRC). According to a classification scheme(5), an estimated BCF of 6(SRC), from an estimated log Kow of 1.65(6) and a regression-derived equation(7), suggests the potential for bioconcentration in aquatic organisms is low(SRC). Biodegradation data in water were not available(SRC, 2010).|ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), chlorotrifluoroethylene, which has a vapor pressure of 4.59X10+3 mm Hg at 25 °C(2), is expected to exist solely as a gas in the ambient atmosphere. Gas-phase chlorotrifluoroethylene is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be 2.5 days(SRC), calculated from its rate constant of 7.0X10-12 cu cm/molecule-sec at 25 °C(3). The rate constant for the vapor-phase reaction of chlorotrifluoroethylene with ozone has been estimated as 0.002X10-17 cu cm/molecule-sec at 25 °C(SRC) that was derived using a structure estimation method(4). This corresponds to an atmospheric half-life of about 720 days at an atmospheric concentration of 7X10+11 ozone molecules per cu cm(5). The chlorine-atom initiated oxidation of chlorotrifluoroethylene in the atmosphere gives CClF2CF(O) as the major product; the quantum yield of oxidation for this reaction is >1000 relative to the quantum yield for olefin(6). A rate constant of 2.7X10-11 cm cu/mol sec is reported for the reaction of chlorotrifluoroethylene with atomic oxygen(7). Chlorotrifluoroethylene does not contain chromophores that absorb at wavelengths >290 nm(8), and therefore is not expected to be susceptible to direct photolysis by sunlight(SRC).

The rate constant for the vapor-phase reaction of chlorotrifluoroethylene with photochemically-produced hydroxyl radicals is 7.0X10-12 cu cm/molecule-sec at 25 °C(1). This corresponds to an atmospheric half-life of about 2.5 days at an atmospheric concentration of 5X10+5 hydroxyl radicals per cu cm(2). Chlorotrifluoroethylene is not expected to undergo hydrolysis in the environment due to the lack of functional groups that hydrolyze under environmental conditions(3). Chlorotrifluoroethylene does not contain chromophores that absorb at wavelengths >290 nm(3), and therefore is not expected to be susceptible to direct photolysis by sunlight(SRC).|The chlorine-atom initiated gas phase, room temperature oxidation of chlorotrifluoroethylene proceeds by a long chain free radical process(1) with the major product (95%) being CClF2CF(O)(2). The quantum yield of oxidation for this reaction is >1000 relative to the quantum yield for olefin(2). The ozonolysis of chlorotrifluoroethylene proceeds through chain oxidation, carried by a diradical mechanism which is inhibited in the presence of O2. The major product of the reaction is the corresponding carbonyl product(1). The rate constant for the vapor-phase reaction of chlorotrifluoroethylene with ozone has been estimated as 0.002X10-17 cu cm/molecule-sec at 25 °C(SRC) that was derived using a structure estimation method(3). This corresponds to an atmospheric half-life of about 720 days at an atmospheric concentration of 7X10+11 ozone molecules per cu cm(4). The primary product of this reaction is the corresponding carbonyl product(1). In the reaction of atomic oxygen with chlorotrifluoroethylene, CF2O and CFClO were reported as products with CF2O the more important; CFClO may have been a contaminant(1). A rate constant of 2.7X10-11 cm cu/mol sec is reported for the reaction of chlorotrifluoroethylene with atomic oxygen using flash photolysis and kinetic spectroscopy(5). Chlorotrifluoroethylene has a measured half-life of approximately 42 days in landfill leachate. It degrades in less than a day in sulfide-containing buffer(6).

An estimated BCF of 6 was calculated in fish for chlorotrifluoroethylene(SRC), using an estimated log Kow of 1.65(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC).

Using a structure estimation method based on molecular connectivity indices(1), the Koc of chlorotrifluoroethylene can be estimated to be 95(SRC). According to a classification scheme(2), this estimated Koc value suggests that chlorotrifluoroethylene is expected to have high mobility in soil. Chlorotrifluoroethylene is believed to be more mobile than 1,1,2-trichloro-1,2,2-trifluoroethane (CFC-113) as it is less halogenated; CFC-113 has a retardation factor of approximately 10 in a sand and gravel aquifer with an organic carbon content of 0.06%(3).

The Henry's Law constant for chlorotrifluoroethylene is estimated as 0.31 atm-cu m/mole(SRC) using a fragment constant estimation method(1). This Henry's Law constant indicates that chlorotrifluoroethylene is expected to volatilize rapidly from water surfaces(2). Based on this Henry's Law constant, the volatilization half-life from a model river (1 m deep, flowing 1 m/sec, wind velocity of 3 m/sec)(2) is estimated as 3 hours(SRC). The volatilization half-life from a model lake (1 m deep, flowing 0.05 m/sec, wind velocity of 0.5 m/sec)(2) is estimated as 4 days(SRC). Chlorotrifluoroethylene's Henry's Law constant indicates that volatilization from moist soil surfaces may occur(SRC). Chlorotrifluoroethylene is expected to volatilize from dry soil surfaces(SRC) based upon a vapor pressure of 4.59X10+3 mm Hg(3).

According to the 2006 TSCA Inventory Update Report, the number of persons reasonably likely to be exposed in the industrial manufacturing, processing, and use for chlorotrifluoroethylene is 100-999; the data may be greatly underestimated(1).|Occupational exposure to chlorotrifluoroethylene may occur through inhalation and dermal contact with this compound at workplaces where chlorotrifluoroethylene is produced or used. (SRC)

After exposure of rabbits to trifluorochloroethylene at 0.1%, the alveolar absorption rate was 5.80%. Trifluorochloroethylene was detected in blood and urine. The kidney, bone, and lung had the highest distribution among various organs examined.

Two metabolites of CTFE were identified as potent nephrotoxins in male rats, S-(2-chloro-1,1,2-trifluoroethyl)glutathione (CTFG) and S-(2-chloro-1,1,2-trifluoroethyl)cysteine (CTFC). In this investigation both CTFG and CTFC were synthesized and given to the male rats at dose levels of 50 umol/kg of CTFG or 100 umol of CTFC. It was concluded that the metabolites of CTFE are the active nephrotoxins, not CTFE.|This study describes in vivo bioactivation of CTFE which proceeds as follows: hepatic glutathione S-conjugate formation, peptidase-catalyzed metabolism of the glutathione S-conjugates to the corresponding cysteine S-conjugates, uptake of cysteine S-conjugates by the kidneys, and renal cysteine conjugate beta-lyase-catalyzed beta-elimination of a thiol. The CTFE conjugate was shown to be capable of acylating renal proteins using (19)F NMR.|Since halogenated vinyl cysteine conjugates are known to be potent nephrotoxicants, chlorotrifluoroethylene was studied for its ability to be metabolically activated to the cysteine conjugate. This was shown not to occur in a biological system. However, if a glutathione adduct of chlorotrifluoroethylene is synthesized, this adduct was shown to degrade non-enzymatically to form the cysteine conjugate. Thus, incubation of chlorotrifluoroethylene with a renal cortex brush border preparation high in C-S lyase did not result in the formation of pyruvate, indicating the lack of ability of a renal preparation to directly activate chlorotrifluoroethylene presumably because of the inability to form the glutathione adduct.|Chlorotrifluoroethylene, a substrate for glutathione S-transferase activity in rat hepatic cytosolic and microsomal fractions, was investigated, wherein the rates of reaction were determined by measuring glutathione disappearance, at 5-15 or 35-70 nmol/min/mg of cytosolic or microsomal protein, respectively. A product of the cytosol-catalyzed reaction between chlorotrifluoroethylene and glutathione was S-(2-chloro-1,1,2-trifluoroethyl)glutathione. The glutathione S-transferase-catalyzed addition reaction with a halogenated olefin may be of toxicological significance.|For more Metabolism/Metabolites (Complete) data for Chlorotrifluoroethylene (9 total), please visit the HSDB record page.

Trichloroethylene, 1.0%, Chlorodifluoroethylene 0.05%

Inhalation causes dizziness, nausea, vomiting; liver and kidney injury may develop after several hours and cause jaundice and necrosis of the kidney. Contact with liquid causes frostbite of eyes and possibly of skin. (USCG, 1999)

Call a physician after all exposures to this compound; it is more toxic than most of the closely related propellant gases. INHALATION: remove victim to fresh air; enforce bed rest; administer oxygen for 30 min. of every hour for 6 hours, even if no symptoms appear. SKIN: if frostbite has occured, apply warm water and treat burn. (USCG, 1999)

Fresh air, rest.

ON FROSTBITE: rinse with plenty of water, do NOT remove clothes.

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

1,1,2-trifluoro-2-chloroethene

The substance can be absorbed into the body by inhalation.

Dizziness. Nausea.

ON CONTACT WITH LIQUID: FROSTBITE.

GRADES: Technical, 99.0%

All other basic organic chemical manufacturing|Ethene, 1-chloro-1,2,2-trifluoro-: ACTIVE|Selection of plastic films for food packaging.|1,1,2-TRIFLUORO-1-BROMO-2-CHLOROETHANE WAS DEHYDROBROMINATED TO FORM TOXIC TRIFLUOROCHLOROETHYLENE WHEN THE FLUOROCARBON ANESTHETIC WAS USED IN CONJUNCTION WITH SODA LIME IN ANESTHESIA.

Chlorotrifluoroethylene was detected in groundwater using a GC/MS with a 30-m DB-624 analytical column. The GC was cooled to -5 °C with liquid CO2 for analysis.

Fire Hazards -> Flammable - 4th degree, Reactive - 3rd degree|Cosmetics -> Film forming