Zinc chloride

136.28600

133.86700

231-592-0

1064

529648

1840|2331

DTXSID2035013

White, very deliquesce granules, or fused pieces or rods|White, hygroscopic crystals|White particulate dispersed in air /Zinc chloride fume/

B - Blood and blood forming organs

2827399000

0

1.37650

clear to cloudy colorless or faintly yellow

2.907 g/cm³ @ Temp: 25 °C

290 °C

732 °C

732ºC

INDEX OF REFRACTION: 1.681; 1.713

432 g/100 mL (25 ºC)

2-8ºC

1 mm Hg ( 428 °C)

Inhalation of zinc chloride fumes can injure lungs and respiratory tract. Dusts or fumes also cause dermatitis, boils, conjunctivitis, and gastrointestinal tract upset (Lewis(Sr), R.J. 1996. Sax’s Dangerous Properties of Industrial Materials, 9th ed. New York: Van Nostrand Reinhold). LD50 oral (rat): 350mg/kg LCLO (inhalation): 1.960 g/m3/10 min

Noncombustible Solid

Odorless|FUME HAS AN ACRID ODOR /ZINC CHLORIDE FUMES/

With much water, some zinc oxylchloride is formed|Heat of fusion: 40.6 cal/g|Hygroscopic; hydrates with 1, 1.5, 2.5, 3, and 4 molecules of water|Aqueous solution is acid to litmus, pH about 4|Evaporation at 20 °C is negligible; a harmful concentration of airborne particles can, however, be reached quickly when dispersed, especially if powdered.

When dissolved in water, it is a strong acid. [Handling Chemicals Safely 1980. p. 964]

Acids, Strong Non-oxidizing

When dissolved in water, ZINC CHLORIDE is a strong acid [Handling Chemicals Safely 1980. p. 964].

Not flammable (USCG, 1999)

Noncombustible Solid

Fume corrosive to metals /zinc chloride fumes/

I

8

UN 2331

2

R36/37/38; R50/53; R34; R22; R51/53; R67; R66; R19; R12; R11

S26; S36; S61; S60; S45; S36/37/39

ZH1400000

C

Store only in original container. Separated from strong bases, strong oxidants and food and feedstuffs. Dry. Well closed. Store in an area without drain or sewer access.

hygroscopic

P260-P280-P301 + P312 + P330-P303 + P361 + P353-P304 + P340 + P310-P305 + P351 + P338

H302-H314-H410

SRP: The most favorable course of action is to use an alternative chemical product with less inherent propensity for occupational exposure or environmental contamination. Recycle any unused portion of the material for its approved use or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material's impact on air quality; potential migration in soil or water; effects on animal, aquatic, and plant life; and conformance with environmental and public health regulations.|Chemical Treatability of Zinc; Concentration Process: Ultrafiltration; Chemical Classification: Metals; Scale of Study: Continuous flow, pilot scale; Type of Wastewater Used: Industrial wastewater; Results of Study: 0.38 ppm effluent concentration. /Zinc/|Chemical Treatability of Zinc; Concentration Process: Miscellaneous sorbents; Chemical Classification: Metals; Scale of Study: Literature review; Type of Wastewater Used: Unknown; Results of Study: Final concentration reduced to 0.1 ppb; SiO2 + CaO slags used. /Zinc/|The proprietary Sulfex process (Permutit Co) has been applied to zinc wastes. The process involves addition of ferrous sulfide, which gradually releases sulfide to precipitate the zinc ... . /Zinc/|For more Disposal Methods (Complete) data for ZINC CHLORIDE (11 total), please visit the HSDB record page.

A mixture of potassium and ... /zinc chloride/ produces a strong explosion on impact ...|Potassium. /Zinc chloride fume/|Flammability of some commercial zinc dusts or powders is attributed to presence of zinc chloride. /Zinc: zinc chloride/

The Approved Drug Products with Therapeutic Equivalence Evaluations List identifies currently marketed prescription drug products, incl zinc chloride, approved on the basis of safety and effectiveness by FDA under sections 505 of the Federal Food, Drug, and Cosmetic Act.|This substance is generally recognized as safe when used as a nutrient in accordance with good manufacturing practice.|This substance is generally recognized as safe when used as a nutrient and/or dietary supplement in accordance with good manufacturing or feeding practice.|Substances migrating to food from cotton and cotton fabrics used in dry food packaging that are generally recognized as safe for their intended use, within the meaning of section 409 of the Act. Zinc chloride is included on this list.|For more FDA Requirements (Complete) data for ZINC CHLORIDE (6 total), please visit the HSDB record page.

Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]: Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Some are oxidizers and may ignite combustibles (wood, paper, oil, clothing, etc.). Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. For electric vehicles or equipment, ERG Guide 147 (lithium ion batteries) or ERG Guide 138 (sodium batteries) should also be consulted. (ERG, 2016)|Not combustible. Gives off irritating or toxic fumes (or gases) in a fire.

|Danger|H302: Harmful if swallowed [Warning Acute toxicity, oral]|P260, P264, P270, P273, P280, P301+P312, P301+P330+P331, P303+P361+P353, P304+P340, P305+P351+P338, P310, P321, P330, P363, P391, P405, and P501|H302 (98.6%): Harmful if swallowed [Warning Acute toxicity, oral]|P260, P261, P264, P270, P271, P273, P280, P301+P312, P301+P330+P331, P303+P361+P353, P304+P340, P305+P351+P338, P310, P312, P321, P330, P363, P391, P403+P233, P405, and P501|Aggregated GHS information provided by 1430 companies from 35 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.|P260, P261, P264, P270, P271, P273, P280, P301+P312, P301+P330+P331, P303+P361+P353, P304+P312, P304+P340, P305+P351+P338, P310, P312, P321, P330, P363, P391, P405, and P501|P260, P264, P270, P280, P301+P312, P301+P330+P331, P303+P361+P353, P304+P340, P305+P351+P338, P307+P311, P310, P321, P330, P363, P405, and P501|P201, P202, P260, P262, P264, P270, P271, P280, P281, P284, P301+P312, P301+P330+P331, P302+P350, P303+P361+P353, P304+P340, P305+P351+P338, P307+P311, P308+P313, P310, P314, P320, P321, P322, P330, P361, P363, P403+P233, P405, and P501

Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]: As an immediate precautionary measure, isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids. SPILL: Increase, in the downwind direction, as necessary, the isolation distance shown above. FIRE: If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2016)

Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]: ELIMINATE all ignition sources (no smoking, flares, sparks or flames in immediate area). Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Stop leak if you can do it without risk. Prevent entry into waterways, sewers, basements or confined areas. Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers. DO NOT GET WATER INSIDE CONTAINERS. (ERG, 2016)

Goggles or face shield. (USCG, 1999)|Employees exposed to zinc chloride should be given instruction in personal hygiene, and in the use of personal protective equipment. Goggles should be provided in areas where danger of spills or splashes exists, skin protection should be provided with rubber gloves, face shields, rubber aprons, gauntlets, suits and rubber boots.|Wear appropriate chemical protective gloves, boots and goggles. Wear positive pressure self-contained breathing apparatus when fighting fires involving this material. /Zinc chloride solid/|Respirator Recommendations: Up to 10 mg/cu m. (Assigned Protection Factor = 10) Any particulate respirator equipped with an N95, R95, or P95 filter (including N95, R95, and P95 filtering facepieces) except quarter-mask respirators. The following filters may be used: N99, R99, P99, N100, P100. Substance reported to cause eye irritation or damage; may require eye protection./(Assigned Protection Factor = 10) Any supplied-air respirator. Substance reported to cause eye irritation or damage; may require eye protection. /Zinc chloride fume/|Respirator Recommendations: Up to 25 mg/cu m. (Assigned Protection Factor = 25) Any supplied-air respirator operated in a continuous-flow mode. Substance reported to cause eye irritation or damage; may require eye protection./(Assigned Protection Factor = 25) Any powered air-purifying respirator with a high-efficiency particulate filter. Substance reported to cause eye irritation or damage; may require eye protection. /Zinc chloride fume/|For more Personal Protective Equipment (PPE) (Complete) data for ZINC CHLORIDE (9 total), please visit the HSDB record page.|(See protection codes)

Not flammable|Mixtures of the powdered chloride and powdered zinc are flammable.

If material on fire or involved in fire: Extinguish fire using agent suitable for type of surrounding fire. Material itself does not burn or burns with difficulty. /Zinc chloride, solid/

Environmental considerations: Land spill: Dig a pit, pond, lagoon, or holding area to contain liquid or solid material. /SRP: If time permits, pits, ponds, lagoons, soak holes, or holding areas should be contained with a flexible impermeable membrane liner./ Cover solid with plastic sheet to prevent dissolving in rain or fire fighting water /Zinc chloride, solid/|Environmental considerations: Water spill: Neutralize with agricultural lime (slaked lime), crushed limestone, or sodium bicarbonate. Use mechanical dredges or lifts to remove immobilized masses of pollutants and precipitates. Adjust pH to neutral (pH 7). /Zinc chloride solid/|Personal protection: P3 filter respirator for toxic particles. Do NOT let this chemical enter the environment. Sweep spilled substance into containers. Carefully collect remainder, then remove to safe place.

If material not on fire and not involved in fire: Keep material out of water sources and sewers. Build dikes to contain flow as necessary. Keep upwind. Avoid breathing vapors or dusts Wash away any material which may have contacted the body with copious amounts of water or soap and water. /Zinc chloride, solid/|SRP: The scientific literature for the use of contact lenses in industry is conflicting. The benefit or detrimental effects of wearing contact lenses depend not only upon the substance, but also on factors including the form of the substance, characteristics and duration of the exposure, the uses of other eye protection equipment, and the hygiene of the lenses. However, there may be individual substances whose irritating or corrosive properties are such that the wearing of contact lenses would be harmful to the eye. In those specific cases, contact lenses should not be worn. In any event, the usual eye protection equipment should be worn even when contact lenses are in place.|If material not on fire and not involved in fire: Keep material out of water sources and sewers. Build dikes to contain flow as necessary. Neutralize spilled material with crushed limestone, soda ash, or lime. Avoid breathing vapors Avoid bodily contact with the material. Do not handle broken packages without protective equipment. Wash away any material which may have contacted the body with copious amounts of water or soap and water. If contact with the material anticipated, wear full protective clothing. /Zinc chloride solution and chemical plant waste/|Prevention /of/ ingestion: do not eat, drink, or smoke during work. Wash hands before eating.|For more Preventive Measures (Complete) data for ZINC CHLORIDE (6 total), please visit the HSDB record page.

/GUIDE 154: SUBSTANCES - TOXIC AND/OR CORROSIVE (NON-COMBUSTIBLE)/ Health: TOXIC; inhalation, ingestion, or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution. /Zinc chloride, anhydrous; Zinc chloride, solution/|/GUIDE 154: SUBSTANCES - TOXIC AND/OR CORROSIVE (NON-COMBUSTIBLE)/ Fire or Explosion: Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Some are oxidizers and may ignite combustibles (wood, paper, oil, clothing, etc.). Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. /Zinc chloride, anhydrous; Zinc chloride, solution/|/GUIDE 154: SUBSTANCES - TOXIC AND/OR CORROSIVE (NON-COMBUSTIBLE)/ Public Safety: CALL Emergency Response Telephone Number ... . As an immediate precautionary measure, isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids. Keep unauthorized personnel away. Stay upwind. Keep out of low areas. Ventilate enclosed areas. /Zinc chloride, anhydrous; Zinc chloride, solution/|/GUIDE 154: SUBSTANCES - TOXIC AND/OR CORROSIVE (NON-COMBUSTIBLE)/ Protective Clothing: Wear positive pressure self-contained breathing apparatus (SCBA). Wear chemical protective clothing that is specifically recommended by the manufacturer. It may provide little or no thermal protection. Structural firefighters' protective clothing provides limited protection in fire situations ONLY; it is not effective in spill situations where direct contact with the substance is possible. /Zinc chloride, anhydrous; Zinc chloride, solution/|For more DOT Emergency Guidelines (Complete) data for ZINC CHLORIDE (8 total), please visit the HSDB record page.

No person may /transport,/ offer or accept a hazardous material for transportation in commerce unless that person is registered in conformance ... and the hazardous material is properly classed, described, packaged, marked, labeled, and in condition for shipment as required or authorized by ... /the hazardous materials regulations (49 CFR 171-177)./|The International Air Transport Association (IATA) Dangerous Goods Regulations are published by the IATA Dangerous Goods Board pursuant to IATA Resolutions 618 and 619 and constitute a manual of industry carrier regulations to be followed by all IATA Member airlines when transporting hazardous materials.|The International Maritime Dangerous Goods Code lays down basic principles for transporting hazardous chemicals. Detailed recommendations for individual substances and a number of recommendations for good practice are included in the classes dealing with such substances. A general index of technical names has also been compiled. This index should always be consulted when attempting to locate the appropriate procedures to be used when shipping any substance or article.

... Corrosivity and irritation to the lungs.|... Can irritate the eyes.|Zinc chloride causes burns ... Data on skin sensitization are not available for zinc chloride. However, based on the accepted derogation and the fact that zinc sulphate is not a skin sensitizer, it is consequently concluded that zinc chloride is not likely to be skin sensitizing.|Skin exposure /causes/ skin burns, pain, /and/ redness.|Zinc salts of strong mineral acids are astringent, corrosive to skin ... /Zinc salts/

Permissible Exposure Limit: Table Z-1 8-hr Time Weighted Avg: 1 mg/cu m. /Fume/|Vacated 1989 OSHA PEL TWA 1 mg/cu m; STEL 2 mg/cu m is still enforced in some states. /Fume/

Recommended Exposure Limit: 10 Hr Time-Weighted Avg: 1 mg/cu m. /Zinc chloride fume/|Recommended Exposure Limit: 15 Min Short-Term Exposure Limit: 2 mg/cu m). /Zinc chloride fume/

Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. Carefully collect remainder. Then store and dispose of according to local regulations.

Store only in original container. Separated from strong bases, strong oxidants and food and feedstuffs. Dry. Well closed. Store in an area without drain or sewer access.

Evaporation at 20 °C is negligible; a harmful concentration of airborne particles can, however, be reached quickly when dispersed, especially if respirable particles (such as fumes) are generated.

The substance is corrosive to the eyes and skin. The aerosol is severely irritating to the respiratory tract. Corrosive on ingestion. Inhalation may cause lung oedema. Inhalation of high concentrations of respirable particles (such as fumes) may cause Adult Respiratory Distress Syndrome (ARDS), pulmonary fibrosis and death.

See Chemical Dangers.

PREVENT DISPERSION OF DUST AND FUMES! IN ALL CASES CONSULT A DOCTOR!

Use local exhaust or breathing protection.

Protective gloves.

Wear safety goggles or eye protection in combination with breathing protection if powder.

Persons in charge of vessels or facilities are required to notify the National Response Center (NRC) immediately, when there is a release of this designated hazardous substance, in an amount equal to or greater than its reportable quantity of 1,000 lb or 454 kg. The toll free number of the NRC is (800) 424-8802. The rule for determining when notification is required is stated in 40 CFR 302.4 (section IV. D.3.b).

Large doses of zinc may inhibit copper absorption in the intestine; zinc supplements should be taken at least 2 hours after the administration of copper supplements. /Zinc supplements/|Thiazide diuretics have been found to increase urinary zinc excretion. /Zinc supplements/|Concurrent use of large amounts of fiber, phosphorus, or phytates with zinc supplements may reduce zinc absorption by formation of nonabsorbable complexes; food containing fiber, phosphorus, or phytates should be taken at least 2 hours after zinc supplements. /Zinc supplements/|Some studies have found that folate can decrease the absorption of zinc, but not in the presence of excessive zinc; other studies have found no inhibition. /Zinc supplements/|For more Interactions (Complete) data for ZINC CHLORIDE (10 total), please visit the HSDB record page.

LD50 Rat oral 350 mg/kg|LD50 Rat ip 58 mg/kg|LD50 Rat (male) oral 1,100 mg/kg|LC50 Rat (female) inhalation < or = 1,975 mg/cu m/10 min|For more Non-Human Toxicity Values (Complete) data for ZINC CHLORIDE (11 total), please visit the HSDB record page.

... AS FLUX IN SOLDERING. ... HANDLING RAILWAY TIES IMPREGNATED WITH ZNCL2.|NIOSH (NOES Survey 1981-1983) has statistically estimated that 353,004 workers (87,750 of these are female) are potentially exposed to zinc chloride in the US(1).

Mesh Heading: Mouthwashes|In low concentrations it is astringent and mildly antibacterial. It is used in vaginal douches to supress trichomonal and hemophilus infections. Although it is used in mouthwashes, contact time is too short, and only astringent and not antibacterial action results.|MEDICATION (VET): Rare as caustic in fistulas (20% solution), as paste in chemotherapy of cancers, and on ulcers (2-4%). Some may still use it as antiseptic astringent on eye infections (0.1-0.2% solution).|Astringent for corn and callus treatment|For more Therapeutic Uses (Complete) data for ZINC CHLORIDE (10 total), please visit the HSDB record page.

FDA Pregnancy Risk Category: C /RISK CANNOT BE RULED OUT. Adequate, well controlled human studies are lacking, and animal studies have shown risk to the fetus or are lacking as well. There is a chance of fetal harm if the drug is given during pregnancy; but the potential benefits may outweigh the potential risk./ /Zinc supplements; parenteral zinc/|Zinc supplements should be taken at least 1 hour before or 2 hours after meals, since many foods may impair the absorption of zinc. If gastric irritation occurs, then zinc supplements may be taken with meals; however, the zinc will be less bioavailable. /Zinc supplements/|In most cases, parenteral administration is indicated only when oral administration is not acceptable (for example, in nausea, vomiting, preoperative and postoperative conditions) or possible (for example, in malabsorption syndromes or following gastric resection). /Zinc supplements/|Zinc injection that contains benzyl alcohol as a preservative should not be used in newborn and immature infants. The use of benzyl alcohol in neonates has been associated with a fatal toxic syndrome consisting of metabolic acidosis and CNS, respiratory, circulatory, and renal function impairment. /Zinc supplements/|For more Drug Warnings (Complete) data for ZINC CHLORIDE (6 total), please visit the HSDB record page.

Solutions for rinsing the mouth, possessing cleansing, germicidal, or palliative properties. (From Boucher's Clinical Dental Terminology, 4th ed) (See all compounds classified as Mouthwashes.)

In humans subjected to low doses of (65)zinc chloride and whole-body measurements ... /it was/ estimated absorption to range from 58% to 77% in 5 controls, and from 16% to 42% in 3 patients suffering from acrodermatitis enterohepatica. The whole-body zinc retention was measured for 34 days ... One week after oral tracer dose of 2 ug zinc chloride to mice, the highest concentrations were found in bone tissue followed by liver and kidney.|The whole-body retention at 95 hr after intravascular injection of carrier-free (65)zinc chloride to mature male rats amounted to 78.3% of the dose.|In one study, 95 hr after injection of (65)zinc chloride to rats, 20.1% of the dose was recovered in feces and only 0.6% in urine ...|In mice given 0.3 ugzinc chloride iv, about 50% of the total dose was recovered in feces within a week. the corresponding value in 1 wk for dogs given 6.5 ug zinc chloride was about 20%. Urinary excretion for the same period was well below 5% of the dose in both species ... Biliary excretion of zinc in rats was found to be 4% over a period of 48 hr following a single iv dose of 0.1 mg (65)zinc chloride.|For more Absorption, Distribution and Excretion (Complete) data for ZINC CHLORIDE (17 total), please visit the HSDB record page.

Hepatocytes were grown in monolayer culture for 22 hr and subsequently treated with zinc chloride (100 uM) for 24 hr which produced a 15-fold increase in metallothionein proteins (MT) concentration. Following pretreatment with zinc chloride, hepatocytes were treated with 20 or 40 uM silver nitrate for 24 hr, and cytotoxicity was then assessed by enzyme leakage and loss of intracellular potassium. The toxicity of silver was significantly less in the zinc-pretreated cells. Furthermore, although zinc pretreatment had no appreciable effect on the hepatocellular uptake of silver, it did alter the subcellular distribution, and silver accumulated more in the cytosol and less in the nuclear, mitochondrial, and microsomal fractions. Silver in the cytosol of control cells was bound primarily to high molecular weight proteins, whereas silver was mainly associated with MT in the zinc-pretreated cells. Zinc-induced MT in rat primary hepatocyte cultures protects against silver-induced cytotoxicity which results from the binding of silver to MT with a concomitant reduction of metal content in critical organelles and proteins.

Impurities include iron and manganese which are removed through precipitation after partial neutralization with zinc oxide or other alkali and oxidation with chlorine or sodium hypochlorite

Solid or water solution is astringent and can irritate the eyes. When ingested, can cause intoxication, severe irritation of stomach, nausea, vomiting, and diarrhea. (USCG, 1999)|Corrosives

INGESTION: give large volumes of water and induce vomiting; repeat process; call a doctor. EYES: wash with water for at least 15 min. (USCG, 1999)|(See procedures)

Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer immediately for medical attention.

Rinse skin with plenty of water or shower for at least 15 minutes. Refer for medical attention .

Rinse with plenty of water for several minutes (remove contact lenses if easily possible). Refer immediately for medical attention.

This brief report describes the clinical course and management of a child who ingested a zinc chloride solution used in a lead soldering process. Injury was limited to bleeding from esophageal erosions and hematemesis. A single small dosage of calcium disodium edetate was effective in normalizing the serum zinc level.|Supportive care ... is indicated for acute zinc chloride inhalation. This may require ventilatory support with positive end-expiratory pressure, antibiotics, steroids, and maintenance of cardiac output.|Zinc chloride... /is a/ highly corrosive agent with severe systemic toxicity. Ingestion of /this/ substance causes life-threatening illness from cationic metal exposure. The local corrosive effects, though of great concern, are less consequential than the manifestations of systemic absorption. For this reason, aggressive decontamination with gentle nasogastric tube aspiration and placement of activated charcoal serve as primary gestures in the initial management of patients with these ingestions... . Some of these patients will also require chelation therapy. The local affects of /this agent/ can be managed supportively and directly assessed after systemic absorption has been prevented or treated.|Treatment of overdose: Dilute with milk or water. Specific treatment: Intramuscular or intravenous edetate calcium disodium ... . /Zinc supplements/|For more Antidote and Emergency Treatment (Complete) data for ZINC CHLORIDE (12 total), please visit the HSDB record page.

/HUMAN EXPOSURE STUDIES/ At exposure to 40 mg/cu m zinc chloride aerosol a metallic taste was detected. Experimental exposure to zinc chloride for 2 minutes resulted in slight nausea and some cough at 80 mg/cu m in the majority of human subjects, whereas at 120 mg/cu m irritation of the nose, throat and chest were noted. Exposure to 4,800 mg/cu m for 30 minutes induced pulmonary effects.[European Chemicals Bureau; EU Risk Assessment Report- Zinc chloride, Vol.45 p.44 (2004). Available from, as of July 10, 2006: http://esis.jrc.ec.europa.eu/]|/HUMAN EXPOSURE STUDIES/ Exposure to zinc chloride fume levels between 0.07 and 0.4 mg/cu m for 30 min failed to elicit sensory effects. An average concentration of 4.8 mg/cu m over a 30-min period caused mild, transient irritation of the respiratory tract in bearing manufacture workers.[Bingham, E.; Cohrssen, B.; Powell, C.H.; Patty's Toxicology Volumes 1-9 5th ed. John Wiley & Sons. New York, N.Y. (2001)., p. 2:278]|/SIGNS AND SYMPTOMS/ Eye exposure /causes/ pain, redness, /and/ severe deep burns.[IPCS, CEC; International Chemical Safety Card on Zinc Chloride. (Date of review: March 2002). Available from, as of July 13, 2006: http://www.inchem.org/documents/icsc/icsc/eics1064.htm]|/SIGNS AND SYMPTOMS/ Dermal toxicity following exposure to zinc chloride has resulted from handling ... and inhalation of mists or fumes may give rise to irritation of GI or respiratory tract. Gray cyanosis, dermatosis and ulceration of nasal passages have resulted from inhalation of this caustic material.[Doull, J., C.D. Klaassen, and M. D. Amdur (eds.). Casarett and Doull's Toxicology. 2nd ed. New York: Macmillan Publishing Co., 1980., p. 461]|For more Human Toxicity Excerpts (Complete) data for ZINC CHLORIDE (33 total), please visit the HSDB record page.

hexite

The substance can be absorbed into the body by inhalation and by ingestion.|inhalation, skin and/or eye contact

irritation eyes, skin, nose, throat; conjunctivitis; cough, copious sputum; dyspnea (breathing difficulty), chest pain, pulmonary edema, pneumonitis; pulmonary fibrosis, cor pulmonale; fever; cyanosis; tachypnea; skin burns

Cough. Sore throat. Burning sensation. Laboured breathing. Shortness of breath. Symptoms may be delayed.

Redness. Pain. Skin burns.

Redness. Pain. Severe burns.

Eyes, skin, respiratory system, cardiovascular system

(2001) 1410 thousand metric tons zinc. /Apparent, all forms/|(2002) 1420 thousand metric tons zinc. /Apparent, all forms/|(2003) 1340 thousand metric tons zinc. /Apparent, all forms/|(2004) 1400 thousand metric tons zinc. /Apparent, all forms/|(2005) 1370 thousand metric tons zinc. /Apparent, all forms/

Grades: CP, Technical. fused; crystal; granulated; 62.5% solution; 50% solution; USP.|8 mesh, 99.5% purity grade, 250- 1000-, and 2500 g lots /available/|99.999% pure, ultradry /available/|Trade Names: Tinning Flux (U.S. Dept. Transportation); A13-04470; Zinctrace (U.S.)|For more Formulations/Preparations (Complete) data for ZINC CHLORIDE (6 total), please visit the HSDB record page.

Agriculture, forestry, fishing and hunting|Zinc chloride (ZnCl2): ACTIVE|It is a substance that migrates to food from packaging materials.|A toothpaste was prepared containing 4.0% zinc chloride, 45% glycerol and other adjuvants used in treatment of gingivitis.

Analyte: zinc chloride; matrix: chemical identification; procedure: reaction with sodium acetate or ammonium sulfide yields a white precipitate, with hydrogen sulfide, that is insoluble in acetic acid but soluble in hydrochloric acid; reaction with potassium ferricyanide yields a white precipitate that is insoluble in hydrochloric acid (zinc test)|Analyte: zinc chloride; matrix: chemical identification; procedure: reaction with silver nitrate yields a white, curdy precipitate that is insoluble in nitric acid but soluble in ammonium hydroxide (chloride test)|Analyte: zinc chloride; matrix: chemical purity; procedure: dissolution in water; addition of ammonia-ammonium chloride buffer solution and eriochrome black indicator; titration with edetate disodium to a deep blue endpoint|Analyte: zinc chloride; matrix: pharmaceutical preparation (injection solution); procedure: atomic absorption spectrophotometry with detection at 213.8 nm and comparison to standards (chemical identification)|Analyte: zinc chloride; matrix: pharmaceutical preparation (injection solution); procedure: determination of absorbances at the zinc emission line at 213.8 nm with atomic absorption spectrophotometry equipped with a zinc hollow-cathode lamp and an air-acetylene flame and comparison to standards (chemical purity)

Human Drugs -> FDA Approved Drug Products with Therapeutic Equivalence Evaluations (Orange Book) -> Active Ingredients|Health Hazards -> Corrosives|Cosmetics -> Oral care; Soothing