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Valine

Valine structure

CAS No:
7004-03-7
Formula:
C5H11NO2
Chemical Name:
Valine
Synonyms:
DL-Aminovaleic Acid;1-2-Amino-3-methylbutyric acid;Valine USP/EP/BP;VALINE
Categories:
Biochemical Engineering > Amino Acids and Proteins

Description

Solid

Valine(2-amino-3-methylbutyric acid) is one of the 20 amino acids that make up proteins. It is an essential 8 amino acids and glucogenic amino acids for the human body. And Valine works with isoleucine and leucine to promote normal body growth, repair tissues, regulate blood sugar, and provide the required energy.

ChEBI: L-valine is the L-enantiomer of valine. It has a role as a nutraceutical, a micronutrient, a human metabolite, an algal metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a mouse metabolite. It is a pyruvate family amino acid, a proteinogenic amino acid, a valine and a L-alpha-amino acid. It is a conjugate base of a L-valinium. It is a conjugate acid of a L-valinate. It is an enantiomer of a D-valine. It is a tautomer of a L-valine zwitterion.

Valine Basic Attributes

Molecular Weight：

Exact Mass：

117.15

EC Number：

200-773-6

Characteristics

PSA：

63.3

Physical Properties：

Valine, White crystal or crystalline powder; odorless, slightly sweet and then bitter. Soluble in water, almost insoluble in ethanol.

XLogP3：

-2.26

Appearance：

Solid

Density：

1.32 g/cm³

Melting Point：

315° C (under decomposition).

Boiling Point：

Sublimes

Water Solubility：

H2O: 58.5 mg/mL

Vapor Pressure：

5.55X10-9 mm Hg at 25 deg C (est)

Specific rotation：

Specific optical rotation: +22.9 deg at 23 °C/D (c = 0.8 in 20% HCl). Molecular rotation: + 33.1 deg at at sodium line (5N HCl); + 72.6 deg at sodium line (glacial acetic acid)

Odor：

virtually odorless

PKA：

pKa1 2.28,pKa2 9.54（25℃）

Valine Use and Manufacturing

Valine works with two other high-concentration amino acids (isoleucine and leucine) to promote normal growth, repair tissues, regulate blood sugar, and provide necessary energy. In addition, valine's role includes stimulating the central nervous system, which is essential for proper mental function. During strenuous physical activity, valine can provide muscles with extra energy to produce glucose, preventing muscle weakness. It also helps remove excess nitrogen (a potential toxin) from the liver and transports the nitrogen the body needs to various parts of the body. Valine may also help treat liver and gallbladder diseases, as well as damage to these organs caused by alcoholism and drug abuse. Valine supplements may be considered for those engaged in heavy physical activity, those on low-protein diets, and bodybuilders. Although available in standalone forms, it is best taken with isoleucine and leucine. Choosing a mixed valine supplement is more convenient. However, it is important to note that excessive valine intake can lead to skin sensitivities and even hallucinations. Furthermore, too much valine in the diet can increase the amount of ammonia in the body, which can have a damaging effect on liver and kidney function.

Drug Function and Efficacy

Essential amino acids are the basic units for protein synthesis. Lack of these amino acids will lead to protein synthesis disorders in the body.

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Compound amino acid (8) vitamin (11) capsules
Ingredients	This product is a compound preparation, its components are: 8 essential amino acids and 11 vitamins.
Indication	Not yet clear.
Specifications	Compound
Manufacturer	Guizhou Shenqi Pharmaceutical Co., Ltd.

Compound Leucine Granules (3AA)
Ingredients	This product is a compound preparation, each bag of which contains 1.375g of leucine, 1.125g of isoleucine and 1.050g of valine.
Indication	There were no reports of drug interactions.
Specifications	14.5g
Manufacturer	Taiyuan Zhenxing Pharmaceutical Co., Ltd.

Valine
Manufacturer	Shantou Jiahe Biologic Technology Co., Ltd.

See More Related Drugs

Registered Holders

Yuanda Bafeng (Hubei) Pharmaceutical Co., Ltd.

China
Active
Shanghai Primano Amino Acid Co., Ltd.

China
Active
Jinyao Pharmaceutical Co., Ltd.

China
Active

See More Registered Holders

Recommended Suppliers of Valine

Hebei Shunxing Import and Export Co.,Ltd Contact Supplier

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CAS No.: 7004-03-7

Grade: Pharmaceutical Grade

Content: 99.9%

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CAS No.: 7004-03-7

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