2,2',2''-(1,2,3-Benzenetriyltrisoxy)tris(N,N,N-triethylethanaminium)
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2,2',2''-(1,2,3-Benzenetriyltrisoxy)tris(N,N,N-triethylethanaminium)
structure -
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CAS No:
7006-17-9
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Formula:
C30H60N3O3+3
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Chemical Name:
2,2',2''-(1,2,3-Benzenetriyltrisoxy)tris(N,N,N-triethylethanaminium)
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Synonyms:
Flaxedil;Gallamine;Gallamine Triethiodide;Gallamine Triethochloride;Gallamine Triethyl Iodide;Gallamonium Iodide;Iodide, Gallamine Triethyl;Iodide, Gallamonium;Triethiodide, Gallamine;Triethochloride, Gallamine
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CAS No:
Description
Solid
Solid
2-[2,3-bis[2-(triethylammonio)ethoxy]phenoxy]ethyl-triethylammonium is an aromatic ether.|A synthetic nondepolarizing blocking drug. The actions of gallamine triethiodide are similar to those of TUBOCURARINE, but this agent blocks the cardiac vagus and may cause sinus tachycardia and, occasionally, hypertension and increased cardiac output. It should be used cautiously in patients at risk from increased heart rate but may be preferred for patients with bradycardia. (From AMA Drug Evaluations Annual, 1992, p198)
2,2',2''-(1,2,3-Benzenetriyltrisoxy)tris(N,N,N-triethylethanaminium) Basic Attributes
510.828
510.463
VYJ027LZ05
DTXSID5048392
Drug Information
Drugs that bind to nicotinic cholinergic receptors (RECEPTORS, NICOTINIC) and block the actions of acetylcholine or cholinergic agonists. Nicotinic antagonists block synaptic transmission at autonomic ganglia, the skeletal neuromuscular junction, and at central nervous system nicotinic synapses. (See all compounds classified as Nicotinic Antagonists.)|Drugs that interrupt transmission at the skeletal neuromuscular junction without causing depolarization of the motor end plate. They prevent acetylcholine from triggering muscle contraction and are used as muscle relaxants during electroshock treatments, in convulsive states, and as anesthesia adjuvants. (See all compounds classified as Neuromuscular Nondepolarizing Agents.)
Flaxedil
2,2',2''-(1,2,3-Benzenetriyltrisoxy)tris(N,N,N-triethylethanaminium) Use and Manufacturing
Human Drugs -> FDA Approved Drug Products with Therapeutic Equivalence Evaluations (Orange Book) -> Active Ingredients
Computed Properties
Molecular Weight:510.8
XLogP3:5.3
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:21
Exact Mass:510.46346778
Monoisotopic Mass:510.46346778
Topological Polar Surface Area:27.7
Heavy Atom Count:36
Formal Charge:3
Complexity:489
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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2,2',2''-(1,2,3-Benzenetriyltrisoxy)tris(N,N,N-triethylethanaminium)
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