2,6-Pyridinedicarboxylicacidmonomethylester
-
2,6-Pyridinedicarboxylicacidmonomethylester
structure -
-
CAS No:
7170-36-7
-
Formula:
C8H7NO4
-
Chemical Name:
2,6-Pyridinedicarboxylicacidmonomethylester
-
Synonyms:
6-carbomethoxypicolinic acid;6-(Methoxycarbonyl)picolinic acid;Monomethyl 2,6-Pyridinedicarboxylate;6-methoxycarbonyl-2-pyridinecarboxylic acid;2,6-Pyridinecarboxylic acid MonoMethyl ester;2,6-Pyridinedicarboxylic acid, 2-methyl ester;6-(methoxycarbonyl)pyridine-2-carboxylic acid;2,6-PYRIDINEDICARBOXYLIC ACID, MONOETHYL ESTER;2,6-PYRIDINEDICARBOXYLIC ACID MONOMETHYL ESTER;PYRIDINE-2,6-DICARBOXYLIC ACID MONOMETHYL ESTER
- Categories:
-
CAS No:
2,6-Pyridinedicarboxylicacidmonomethylester Basic Attributes
181.15
181.037506
DTXSID00398575
2933399090
Safety Information
Xi
P264, P280, P302+P352, P305+P351+P338, P321, P332+P313, P337+P313, P362
H315
|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 2 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
2,6-Pyridinedicarboxylicacidmonomethylester Use and Manufacturing
To a solution of 20 (10.0 g, 51.2 mmol) in MeOH (300 mL) was added KOH (2.89 g, 51.2 mmol) and themixture was stirred overnight at rt. After the removal of the solvent, the residue was diluted with water. Theaqueous layer was washed with AcOEt and acidified with conc. HCl aq, and then the mixture was extracted withthe solution of CHCl3/isopropanol (3/1 (v/v)). The organic layer were dried over MgSO4 and concentrated invacuo to give 21 (8.17 g, 87 percent) as a white solid.Dimethyl 2, 6-pyridinedicarboxylate (7.0 g, 36.0 mmol) was dissolved in methanol (150 mL), then the mixture was cooled to 0 °C and KOH (2.1 g, 36.0 mmol) was slowly added, the reaction mixture was stirred at 0 °C for 2 h and then at room temperature for 24 h. After that the solvent was removed under reduced pressure, and the residue was suspended in HExample 103 A solution of (1) (5.85 g, 30.0 mmol) in methanol (150 mL) was cooled to 0 °C. After KOH pellets (1.76 g, 31.0 mmol) were added, the reaction mixture was stirred at 0 °C for 2 h and then at room temperature for 24 h. The solvent was removed under reduced pressure, and the residue was suspended in HA general synthetic procedure is as follows. Pyridine-2, 6-dicarboxylic acid (1, 1.5 g, 8.98 mmol) was mixed with 24 mL of SOCl
Computed Properties
Molecular Weight:181.15
XLogP3:0.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:181.03750770
Monoisotopic Mass:181.03750770
Topological Polar Surface Area:76.5
Heavy Atom Count:13
Complexity:216
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Recommended Suppliers of 2,6-Pyridinedicarboxylicacidmonomethylester
-
![China]()
CN
5 YRS
Business licensedTrader Supplier of Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals,Biochemicals,Pharmaceuticals,Screening Compounds,Food Additives
Learn More Other Chemicals
-
(2E)-3-(1-METHYL-1H-PYRROL-2-YL)ACRYLIC ACID
51485-76-8
-
Benadryl N-oxide hydrochloride
13168-00-8
-
6-CHLORO-3-IODO-IMIDAZO[1,2-A]PYRIDINE
885275-59-2
-
(2-Bromophenyl)diphenylphosphine Formula
62336-24-7
-
1-Morpholinocyclopentene Formula
936-52-7
-
4-[2-(Boc-amino)ethoxy]-benzoic acid Formula
168892-66-8
-
3-amino-5-bromopyridine-2-carboxylic acid Structure
870997-85-6
-
2-Amino-6-methylpyridine Structure
1824-81-3
-
What is 3-Bromo-2-methylthiophene
30319-05-2
-
What is THIOPHEN-2-YLMETHYL-PHOSPHONICACIDDIETHYLESTER
2026-42-8
2,6-Pyridinedicarboxylicacidmonomethylester
SDSRequest for Quotation