Selenium sulfide

143.09

143.09

231-303-8

Z69D9E381Q

2657

DTXSID0042375

C44444

Red-yellow crystals|Bright orange powder

2830909000

32.09000

0.37990

Red-brown Powder

<100 °C

Decomposes

Insoluble in water.

Store below +30°C.

Oral-rat LD50: 138 mg/kg

Non-combustible; heated, or in contact with water, acid emits highly toxic hydrogen selenide and other gases

Decomposes in aqua regia, and in nitric acid

Slightly water soluble.

Sulfides, Inorganic

SELENIUM DISULFIDE may react vigorously with acids to release hydrogen sulfide gas. May react with oxidizing agents, including inorganic oxoacids, organic peroxides and epoxides.

II

6.1

2657

2

50/53-33-23/25

61-60-45-28A-20/21-28

VS8925000

N-T,N,T

Treasury is ventilated, low temperature and dry; stored and transported separately from acids and food

P261-P273-P301 + P310-P311-P501

H301 + H331-H373-H410

Generators of waste (equal to or greater than 100 kg/mo) containing this contaminant, EPA hazardous waste number D010, U205 must conform with USEPA regulations in storage, transportation, treatment and disposal of waste.|A poor candidate for incineration.

Do not use metal and acid to reduce selenium compounds. This will produce toxic gaseous hydrogen selenide. /Selenium compounds/|Acids, strong oxidizers, chromium trioxide, potassium bromate. /Selenium/

The Generic Animal Drug and Patent Restoration act requires that each sponsor of an approved animal drug must submit to the FDA certain information regarding patents held for the animal drug or its method of use. The Act requires that this information, as well as a list of all animal drug products approved for safety and effectiveness, be made available to the public. Selenium disulfide is included on this list.|Ophthalmic and Topical Dosage Form New Animal Drugs. Selenium disulfide suspension. ... For use as a cleansing shampoo and as an agent for removing skin debris associated with dry eczema, seborrhea, and nonspecific dermatoses. /Selenium disulfide suspension/

WHO; Environmental Health Criteria 58: Selenium (1987). EHC are designed for scientists and administrators responsible for the establishment of safety standards and regulations and provide basic scientific risk evaluations of a wide range of chemicals and groups of chemicals.[Available from, as of April 1, 2011: http://www.inchem.org/documents/ehc/ehc/ehc58.htm#SectionNumber:7.1]|Bioassay of Selsun for Possible Carcinogenicity (1980) Technical Rpt Series No. 199 DHEW Pub No. 80-1755, U.S. Department of Health Education and Welfare, National Cancer Institute, Bethesda, MD 20014

Excerpt from ERG Guide 153 [Substances - Toxic and/or Corrosive (Combustible)]: Combustible material: may burn but does not ignite readily. When heated, vapors may form explosive mixtures with air: indoors, outdoors and sewers explosion hazards. Those substances designated with a (P) may polymerize explosively when heated or involved in a fire. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. Runoff may pollute waterways. Substance may be transported in a molten form. (ERG, 2016)

|Danger|H301+H331 (34.26%): Toxic if swallowed or if inhaled [Danger Acute toxicity, oral; acute toxicity, inhalation]|P260, P261, P264, P270, P271, P273, P284, P301+P310, P304+P340, P310, P311, P314, P320, P321, P330, P391, P403+P233, P405, and P501|Aggregated GHS information provided by 108 companies from 12 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Excerpt from ERG Guide 153 [Substances - Toxic and/or Corrosive (Combustible)]: As an immediate precautionary measure, isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids. SPILL: Increase, in the downwind direction, as necessary, the isolation distance shown above. FIRE: If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2016)

SMALL SPILLS AND LEAKAGE: If you should spill this chemical, use absorbent paper to pick up all liquid spill material. Seal the absorbent paper, as well as any of your clothing which may be contaminated, in a vapor-tight plastic bag for eventual disposal. Wash any surfaces you may have contaminated with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned. STORAGE PRECAUTIONS: You should store this material in a refrigerator. (NTP, 1992)

RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter. (NTP, 1992)|Wear appropriate personal protective clothing to prevent skin contact. /Selenium/|Facilities for quickly drenching the body should be provided within the immediate work area for emergency use where there is a possibility of exposure. [Note: It is intended that these facilities provide a sufficient quantity or flow of water to quickly remove the substance from any body areas likely to be exposed. The actual determination of what constitutes an adequate quick drench facility depends on the specific circumstances. In certain instances, a deluge shower should be readily available, whereas in others, the availability of water from a sink or hose could be considered adequate.] /Selenium/|Respirator Recommendations: Up to 1 mg/cu m: /Selenium/ [Table#5926]|Respirator Recommendations: Emergency or planned entry into unknown concentrations or IDLH conditions: /Selenium/ [Table#5927]|Respirator Recommendations: Escape conditions: /Selenium/ [Table#5928]

If material on fire or involved in fire: Extinguish fire using agent suitable for type of surrounding fire. Material itself does not burn or burns with difficulty. Use water in flooding quantities as fog. Use foam, dry chemical, or carbon dioxide. Keep run-off water out of sewers and water sources.|Personnel protection: Wear positive pressure self-contained breathing apparatus. Wear appropriate chemical protective clothing.

SRP: Wastewater from contaminant suppression, cleaning of protective clothing/equipment, or contaminated sites should be contained and evaluated for subject chemical or decomposition product concentrations. Concentrations shall be lower than applicable environmental discharge or disposal criteria. Alternatively, pretreatment and/or discharge to a permitted wastewater treatment facility is acceptable only after review by the governing authority and assurance that "pass through" violations will not occur. Due consideration shall be given to remediation worker exposure (inhalation, dermal and ingestion) as well as fate during treatment, transfer and disposal. If it is not practicable to manage the chemical in this fashion, it must be evaluated in accordance with EPA 40 CFR Part 261, specifically Subpart B, in order to determine the appropriate local, state and federal requirements for disposal.

SRP: The scientific literature for the use of contact lenses by industrial workers is inconsistent. The benefits or detrimental effects of wearing contact lenses depend not only upon the substance, but also on factors including the form of the substance, characteristics and duration of the exposure, the uses of other eye protection equipment, and the hygiene of the lenses. However, there may be individual substances whose irritating or corrosive properties are such that the wearing of contact lenses would be harmful to the eye. In those specific cases, contact lenses should not be worn. In any event, the usual eye protection equipment should be worn even when contact lenses are in place.|If material not on fire and not involved in fire: Keep sparks, flames, and other sources of ignition away. Keep material out of water sources and sewers. Do not handle broken packages unless wearing appropriate personal protective equipment.|Eye Exposure: If selenium or its inorganic compounds get into the eyes, wash eyes immediately with large amounts of water, lifting the lower and upper lids occasionally. Get medical attention immediately. /Selenium and its inorganic salts/|Personnel protection: Avoid breathing vapors. Keep upwind. Do not handle broken packages unless wearing appropriate personal protective equipment. /Selenium compound, solid, nos/|For more Preventive Measures (Complete) data for SELENIUM DISULFIDE (6 total), please visit the HSDB record page.

/GUIDE 153: SUBSTANCES - TOXIC AND/OR CORROSIVE (COMBUSTIBLE)/ Health: TOXIC; inhalation, ingestion, or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.|/GUIDE 153: SUBSTANCES - TOXIC AND/OR CORROSIVE (COMBUSTIBLE)/ Fire or Explosion: Combustible material: may burn but does not ignite readily. When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards. Those substances designated with a "P" may polymerize explosively when heated or involved in a fire. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. Runoff may pollute waterways. Substance may be transported in a molten form.|/GUIDE 153: SUBSTANCES - TOXIC AND/OR CORROSIVE (COMBUSTIBLE)/ Public Safety: CALL Emergency Response Telephone Number ... As an immediate precautionary measure, isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids. Keep unauthorized personnel away. Stay upwind. Keep out of low areas. Ventilate enclosed areas.|/GUIDE 153: SUBSTANCES - TOXIC AND/OR CORROSIVE (COMBUSTIBLE)/ Protective Clothing: Wear positive pressure self-contained breathing apparatus (SCBA). Wear chemical protective clothing that is specifically recommended by the manufacturer. It may provide little or no thermal protection. Structural firefighters' protective clothing provides limited protection in fire situations ONLY; it is not effective in spill situations where direct contact with the substance is possible.|For more DOT Emergency Guidelines (Complete) data for SELENIUM DISULFIDE (8 total), please visit the HSDB record page.

The International Maritime Dangerous Goods Code lays down basic principles for transporting hazardous chemicals. Detailed recommendations for individual substances and a number of recommendations for good practice are included in the classes dealing with such substances. A general index of technical names has also been compiled. This index should always be consulted when attempting to locate the appropriate procedures to be used when shipping any substance or article.|No person may /transport,/ offer or accept a hazardous material for transportation in commerce unless that person is registered in conformance ... and the hazardous material is properly classed, described, packaged, marked, labeled, and in condition for shipment as required or authorized by ... /the hazardous materials regulations (49 CFR 171-177)./|The International Air Transport Association (IATA) Dangerous Goods Regulations are published by the IATA Dangerous Goods Board pursuant to IATA Resolutions 618 and 619 and constitute a manual of industry carrier regulations to be followed by all IATA Member airlines when transporting hazardous materials.

Contact of preparations containing selenium sulfide with mucous membrane of the eye may cause irritation (eg, stinging). Prolonged contact (eg, night application) of preparations containing selenium sulfide with the skin cause local irritation.

Permissible Exposure Limit: 8 Hr Time Weighted Avg: 0.2 mg/cu m. /Selenium compounds (as Se)/

Recommended Exposure Limit: 10 Hr Time-Weighted Avg: 0.2 mg/cu m. /Selenium; The REL also apply to other selenium compounds (as Se) except selenium hexafluoride./

Listed as a hazardous air pollutant (HAP) generally known or suspected to cause serious health problems. The Clean Air Act, as amended in 1990, directs EPA to set standards requiring major sources to sharply reduce routine emissions of toxic pollutants. EPA is required to establish and phase in specific performance based standards for all air emission sources that emit one or more of the listed pollutants. Selenium cmpds are included on this list. /Selenium cmpds/

U205; A toxic waste when a discarded commercial chemical product or manufacturing chemical intermediate or an off-specification commercial chemical product or manufacturing chemical intermediate.[40 CFR 261.33 (USEPA); U.S. National Archives and Records Administration's Electronic Code of Federal Regulations. Available from, as of March 8, 2011: http://www.ecfr.gov]|D010; A waste containing selenium (such as selenium disulfide) may or may not be characterized as a hazardous waste following testing by the Toxicity Characteristic Leaching Procedure as prescribed by the Resource Conservation and Recovery Act (RCRA) regulations.[40 CFR 261.24 (USEPA); U.S. National Archives and Records Administration's Electronic Code of Federal Regulations. Available from, as of March 8, 2011: http://www.ecfr.gov]

Persons in charge of vessels or facilities are required to notify the National Response Center (NRC) immediately, when there is a release of this designated hazardous substance, in an amount equal to or greater than its reportable quantity of 10 lb or 4.54 kg. The toll free number of the NRC is (800) 424-8802. The rule for determining when notification is required is stated in 40 CFR 302.4 (section IV. D.3.b).

U205; As stipulated in 40 CFR 261.33, when selenium sulfide SeS2, as a commercial chemical product or manufacturing chemical intermediate or an off-specification commercial chemical product or a manufacturing chemical intermediate, becomes a waste, it must be managed according to Federal and/or State hazardous waste regulations. Also defined as a hazardous waste is any residue, contaminated soil, water, or other debris resulting from the cleanup of a spill, into water or on dry land, of this waste. Generators of small quantities of this waste may qualify for partial exclusion from hazardous waste regulations (40 CFR 261.5).|D010; A solid waste containing selenium (such as selenium disulfide) may or may not become characterized as a hazardous waste when subjected to the Toxicity Characteristic Leaching Procedure listed in 40 CFR 261.24, and if so characterized, must be managed as a hazardous waste.

highly toxic

No documented reports of serious toxicity in humans resulting from acute ingestion of selenium sulfide, however, acute toxicity studies in animals suggest that ingestion of large amounts could result in potential human toxicity.

LD50 Rat oral 138 mg/kg|LD50 Mouse oral 370 mg/kg

A bioassay of Selsun for possible carcinogenicity was conducted by applying this substance dermally to ICR Swiss mice. Selsun, an antidandruff shampoo, contains 2.5% selenium sulfide. Groups of 50 mice of each sex were exposed to 0.05 mL of 25% or 50% Selsun in distilled water three times a week on a 2-x 3-cm clipped dorsal surface. Vehicle controls consisted of 50 mice of each sex that were clipped and treated with distilled water. Untreated controls consisted of 50 mice of each sex that were only clipped. Surviving mice were /sacrificed/ and necropsied at week 88. ... Under the conditions of this bioassay, dermal application of Selsun was not carcinogenic for ICR Swiss mice. The study was limited, however, by the relatively short lifespan of this strain of mouse. ... Levels of Evidence of Carcinogenicity: Male Mice: Negative; Female Mice: Negative.

Selenium sulfides are not very water soluble and therefore are relatively immobile in the environment(1).

According to the 2006 TSCA Inventory Update Report, the number of workers reasonably likely to be exposed in the industrial manufacturing, processing, and use of selenium disulfide is 1 to 99 persons; the data may be greatly underestimated(1).

For treatment of tinea versicolor, tinea capitis, dandruff and seborrheic dermatitis of the scalp.

The treatment of pityriasis versicolor by the topical application of selenium sulfide 1% was studied in two groups of patients. Diagnosis and response to therapy was determined by clinical observation. Wood's light fluorescence, and direct microscopic examination. The efficacy of three different therapeutic regimes was studied in one group by the application of the drug to the entire skin for either five minutes, fifteen minutes, or twelve hours for eighteen days. Each method proved equally effective in resolving the infection. Therefore, the cutaneous application of selenium sulfide 1 % for five minutes daily for eighteen days is the recommended treatment for pityriasis versicolor. The percutaneous absorption of selenium sulfide was also studied in another groups who applied the drug to the entire skin for five minutes for eighteen days. Fluorimetric analysis of urinary samples collected on the third and thirteenth days of treatment revealed no significant increase in the excretion of selenium as compared to pretreatment levels. Systemic toxicity was not observed in any of the patients treated. The results suggest that the selenium sulfide is absorbed poorly from the skin and is a safe and effective therapy for pityriasis versicolor.|A 1% lotion of selenium sulfide is used to relieve the itching and flaking of the scalp associated with dandruff. A 1% shampoo or 2.5% lotion of the drug is used for the control of dandruff and of seborrheic dermatitis of the scalp. Dandruff usually responds to treatment, but tends to relapse if therapy is discontinued. If dandruff is left untreated, the resulting problems are those of appearance, and generally no medical disability will result. A 2.5% lotion of selenium sulfide has also been used for the treatment of tinea versicolor.|... As an ointment for application to the lid margins in treatment of Seborrheic blepharitis.|Medication (Vet): Topically in eczemas and dermatomycoses.|Medication (Vet): For use on dogs as a cleansing shampoo and as an agent for removing skin debris associated with dry eczema, seborrhea, and nonspecific dermatoses. /Seleen Suspension, SE Se Shampoo, Dandrex /

It is also not known whether selenium sulfide can cause fetal harm when administered to pregnant women. Selenium sulfide should be used during pregnancy only when clearly needed and should generally not be used for the treatment of tinea versicolor during pregnancy.|Safety of selenium sulfide lotions in infants has not been established. A 1% selenium sulfide lotion should not be used in children younger than 2 years of age unless otherwise directed by a physician.|Contact of preparations containing selenium sulfide with mucous membranes of the eye may cause irritation (e.g., stinging). Prolonged contact (e.g., overnight application) of preparations containing selenium sulfide with the skin may cause local irritation. When selenium sulfide is applied topically for the treatment of tinea versicolor, skin irritation may occur, especially in the genital areas and/or folds of the skin. Selenium sulfide lotions can cause rebound oiliness of the scalp; this effect has been reported following short-term application of a 2.5% lotion and following long-term application of a 1% lotion.|Because of the risk of systemic toxicity, selenium sulfide lotions should not be applied to damaged skin (e.g., open lesions or acute inflammation or exudation of the scalp). Cutaneous sensitization of the scalp or adjacent areas has been reported; application of the drug should be discontinued if sensitization occurs. Since selenium sulfide may cause irritation of the genital areas and/or folds of the skin in patients with tinea versicolor, these areas should be rinsed thoroughly following topical application of the drug. Patients should be advised to avoid contact of the lotion with the eyes since irritation may occur; if the lotion does come in contact with the eye, the eye should be thoroughly rinsed with water. Patients should also be advised to discontinue the drug and contact a physician if the condition worsens or does not improve following regular use of selenium sulfide lotion as directed.|For more Drug Warnings (Complete) data for SELENIUM DISULFIDE (8 total), please visit the HSDB record page.

Selenium sulfide is an antifungal agent often used in shampoos for the treatment of dandruff and seborrheic dermatitis. Selenium sulfide is highly active in inhibiting the growth of P. ovale. It is also a proven cytostatic agent, slowing the growth of both hyperproliferative and normal cells in dandruff and seborrheic dermatitis. A 0.6% micronized form of selenium sulfide is also safe and effective for dandruff.

Drugs used to treat or prevent skin disorders or for the routine care of skin. (See all compounds classified as Dermatologic Agents.)

There is no substantial absorption through intact skin. Absorption has been reported in patients with open lesions on the scalp or in patients using a 1% cream on the back - a patient with scalp lesions that used selenium shampoos had a level of selenium sulfide as high as 32 μg/ml in her urine.|Selenium sulfide does not appear to be absorbed percutaneously through intact skin following topical application to the scalp of a 1% lotion during usual shampooing conditions. The drug can be absorbed percutaneously when applied to damaged skin, and systemic toxicity may occur.|The treatment of pityriasis versicolor by the topical application of selenium sulfide 1% was studied. ... The percutaneous absorption of selenium sulfide was studied in groups who applied the drug to the entire skin for five minutes for eighteen days. Fluorimetric analysis of urinary samples collected on the third and thirteenth days of treatment revealed no significant increase in the excretion of selenium as compared in any of the patients treated.|... Selenium is absorbed through intact skin following overnight topical application of 2.5% selenium sulfide lotion. Selenium is then excreted, at least partially, in urine, for at least a week following treatment. Absorption and excretion of selenium vary on an individual basis. Selenium levels in urine following a single application of selenium sulfide lotion do not indicate that toxic amounts of selenium are being absorbed. Repeated treatments with selenium sulfide result in selenium concentrations in urine which are significantly higher than normal. ...

Topical selenium sulfide may act by an antimitotic action, resulting in a reduction in the turnover of epidermal cells. It also has local irritant, antibacterial, and mild antifungal activity, which may contribute to its effectiveness. An antimitotic mechanism of action is suggested by data showing that selenium sulfide decreases the rate of incorporation of radioactively labeled thymidine into the DNA of dermal epithelial cells. The following organisms are generally considered susceptible to selenium sulfide in vitro: Malassezia furfur, Microsporum sp. including Microsporum audouinii and Microsporum canis, Pityrosporon sp., Trichophyton sp. including Trichophyton schoenleinii and Trichophyton tonsurans. Selenium sulfide has been shown to be sporicidal to T. tonsurans, the most common etiologic agent of tinea capitis. One in-vitro study demonstrated that 2.5% selenium sulfide was equivalent in sporicidal activity to both 1% and 2% zinc pyrithione.|... Selenium sulfide, when absorbed into epithelial tissue, is converted into selenium and sulfide ions, and that the selenium ions block the enzyme systems involved in the growth of epithelial tissue. Selenium sulfide has been shown to have a cytostatic (antimitotic) action resulting in a decreased rate of cell turnover in cells with normal or higher than normal turnover rates.

SYMPTOMS: Symptoms of exposure to this compound include skin, eye and mucous membrane irritation; increase in hair loss, hair discoloration and oiliness or dryness of hair and scalp. ACUTE/CHRONIC HAZARDS: This compound can cause skin, eye and mucous membrane irritation. (NTP, 1992)

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop. SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. IMMEDIATELY call a hospital or poison control center even if no symptoms (such as redness or irritation) develop. IMMEDIATELY transport the victim to a hospital for treatment after washing the affected areas. INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. IMMEDIATELY call a physician and be prepared to transport the victim to a hospital even if no symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing. INGESTION: Some heavy metals are VERY TOXIC POISONS, especially if their salts are very soluble in water (e.g., lead, chromium, mercury, bismuth, osmium, and arsenic). IMMEDIATELY call a hospital or poison control center and locate activated charcoal, egg whites, or milk in case the medical advisor recommends administering one of them. Also locate Ipecac syrup or a glass of salt water in case the medical advisor recommends inducing vomiting. Usually, this is NOT RECOMMENDED outside of a physician's care. If advice from a physician is not readily available and the victim is conscious and not convulsing, give the victim a glass of activated charcoal slurry in water or, if this is not available, a glass of milk, or beaten egg whites and IMMEDIATELY transport victim to a hospital. If the victim is convulsing or unconscious, do not give anything by mouth, assure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital. OTHER: Since this chemical is a known or suspected carcinogen you should contact a physician for advice regarding the possible long term health effects and potential recommendation for medical monitoring. Recommendations from the physician will depend upon the specific compound, its chemical, physical and toxicity properties, the exposure level, length of exposure, and the route of exposure. (NTP, 1992)

Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand-valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR as necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. /Selenium and Related Compounds/|Basic treatment: Establish a patent airway (oropharyngeal or nasopharyngeal airway, if needed). Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for shock and treat if necessary ... . Monitor for pulmonary edema and treat if necessary ... . Treat seizures if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with 0.9% saline (NS) during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 ml/kg up to 200 ml of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool. Administer activated charcoal ... . /Selenium and Related Compounds/|Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious, has severe pulmonary edema, or is in severe respiratory distress. Positive-pressure ventilation techniques with a bag valve mask device may be beneficial. Consider drug therapy for pulmonary edema ... . Consider administering a beta agonist such as albuterol for severe bronchospasm ... .Monitor cardiac rhythm and treat arrhythmias if necessary ... . Start IV administration of D5W /SRP: "To keep open", minimal flow rate/. Use 0.9% saline (NS) or lactated Ringer's (LR) if signs of hypovolemia are present. For hypotension with signs of hypovolemia, administer fluid cautiously. Consider vasopressors if patient is hypotensive with a normal fluid volume. Watch for signs of fluid overload ... . Treat seizures with diazepam or lorazepam ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Selenium and Related Compounds/|Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand-valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR as necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. /Sulfur and related compounds/|For more Antidote and Emergency Treatment (Complete) data for SELENIUM DISULFIDE (8 total), please visit the HSDB record page.

/CASE REPORTS/ ... A woman used selenium sulfide containing shampoo 2 or 3 times weekly for 8 months to cure excoriations of the scalp. One hour after the last wash, she developed tremor, abdominal pain, and occasionally vomited. She had garlic odor in her breath, and the urinary level of selenium 5 days later was 32 ug/mL.

Abbottselsun

In 1975, approx 440 pounds of selenium sulfide were consumed for pharmaceutical and cosmetic products.|(1974) 2.27X10+7 G (CONSUMPTION-PHARMACEUTICAL)

Grade: USP|Seleen Suspension liquid (topical) (Merial Ltd): selenium disulfide, 0.9% w/w and 1% w/v.|SE S2 Shampoo liquid (suspension) (topical ) (Schering-Plough Animal Health Corp): selenium disulfide, 0.9% w/w|Dandrex liquid (suspension) (topical) (Farnam Companies, Inc.): selenium disulfide, 0.9% w/w and 1% w/v|For more Formulations/Preparations (Complete) data for SELENIUM DISULFIDE (8 total), please visit the HSDB record page.

Selenium sulfide (SeS2): ACTIVE

Animal Drugs -> FDA Approved Animal Drug Products (Green Book) -> Active Ingredients|Cosmetics -> Antidandruff