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Squalene

Squalene structure

CAS No:
7683-64-9
Formula:
C30H50
Chemical Name:
Squalene
Synonyms:
2,6,10,14,18,22-Tetracosahexaene, 2,6,10,15,19,23-hexamethyl-;Skvalen;Sqalene;SQUALENE OIL;SQUALENE;SPINACENE;2,6,10,15,19,23-HEXAMETHYL-2,6,10,14,18,22-TETRACOSAHEXAENE;2,6,10,15,19,23-HEXAMETHYL-2, 6, 10, 14, 18, 22-TETRACOSAHEXENE
Categories:
Active Pharmaceutical Ingredients > Vitamins and Minerals Medicines

Description

squalene: An intermediate compoundformed in the synthesis ofcholesterol; it is a hydrocarbon containing30 carbon atoms. The immediateoxidation of squalene tosqualene 2,3-epoxide is the last commonstep in the synthesis of sterolsin animals, plants, and fungi.

Squalene belongs to the group of triterpenoids. Oily liquid. After absorbing oxygen in the air, it is transformed into viscous liquid resembling linseed oil. Melting point -38 ° C, boiling point 280 ° C (17 mm Hg), specific gravity 0.8128 (15/4 ° C), refractive index 1.4965, in cyclohexane UV λmax < 226 nm. Soluble in ether, petroleum ether, acetone and carbon tetrachloride and other fat-soluble solvents, slightly soluble in ethanol and glacial acetic acid, almost insoluble in water. Has a slight pleasant odor. Decomposes when distilled under normal pressure. Gradually absorbs oxygen and resinates when placed in air.

Squalene Basic Attributes

Molecular Weight：

410.72

Exact Mass：

410.391266

EC Number：

203-826-1

DSSTox ID：

DTXSID4064767

Color/Form：

light yellow

HScode：

2901299090

Characteristics

PSA：

XLogP3：

14.1 (est)

Appearance：

light yellow liquid

Density：

0.858 g/mL at 25 °C(lit.)

Melting Point：

−75 °C(lit.)

Boiling Point：

285 °C25 mm Hg(lit.)

Flash Point：

>230 °F

Refractive Index：

n20/D1.494(lit.)

Water Solubility：

Slightly soluble in alcohol; soluble in lipids and organic solvents

Storage Conditions：

2-8°C

Vapor Pressure：

6.3X10-6 mm Hg at 25 deg C (est)

Odor：

Faint agreeable odor

Critical Temperature & Pressure：

Sealed in dry,2-8°C

Safety Information

wgk germany：

safety instructions：

24/25

RTECS Number：

XB6010000

Stability/Shelf Life：

Stable under recommended storage conditions.

Precautionary statement(s)：

P301+P310, P331, P405, P501

Hazard Statements：

H304

Squalene Use and Manufacturing

squalene is like squalane, squalene replenishes skin lipids while softening and smoothing. It helps maintain the skin in good condition. When used in hair care products, it serves as a hairconditioning and anti-static agent.

Spinacene can be used for its antioxidant properties using its essential oils derived from its leaves and stem, including, effective larvacides

Computed Properties

Molecular Weight:410.7
XLogP3:11.6
Rotatable Bond Count:15
Exact Mass:410.391251595
Monoisotopic Mass:410.391251595
Heavy Atom Count:30
Complexity:578
Undefined Bond Stereocenter Count:4
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Drug Function and Efficacy

Not clearly stated

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Uvis brand squalene soft capsules
Specifications	750 mg/capsule

Squalene capsules
Ingredients	Squalene, chemical name is 2,6,10,15,19.23-hexamethyl-2,6,10,14,18-22-tetracarbonhexaene
Indication	It participates in the biosynthesis of cholesterol and various biochemical reactions in the body, promotes biological oxidation and the body's metabolism, improves the body's defense function and stress resistance, accelerates the synthesis of steroid hormones, activates the activity of adenylate cyclase, and enhances the body's endurance and improves cardiac function. After taking squalene, the levels of ceruloplasmin and transferrin, as well as the activities of superoxide dismutase and lactate dehydrogenase, are all increased. Squalene also has the ability to increase the body's tissues' ability to utilize oxygen.
Specifications	0.25g
Manufacturer	Zhejiang Medicine Co., Ltd.

Squalene capsules
Ingredients	Squalene, chemical name is 2,6,10,15,19.23-hexamethyl-2,6,10,14,18-22-tetracarbonhexaene
Indication	It participates in the biosynthesis of cholesterol and various biochemical reactions in the body, promotes biological oxidation and the body's metabolism, improves the body's defense function and stress resistance, accelerates the synthesis of steroid hormones, activates the activity of adenylate cyclase, and enhances the body's endurance and improves cardiac function. After taking squalene, the levels of ceruloplasmin and transferrin, as well as the activities of superoxide dismutase and lactate dehydrogenase, are all increased. Squalene also has the ability to increase the body's tissues' ability to utilize oxygen.
Specifications	0.25g
Manufacturer	Jiangsu Xinfu Pharmaceutical Co., Ltd.

See More Related Drugs

Registered Holders

EVONIK OPERATIONS GMBH

France
Active
Zhejiang Qianyuan Haili Sheng Pharmaceutical Co., Ltd.

China
Active
Zhejiang Anbao Pharmaceutical Co., Ltd.

China
Active

See More Registered Holders

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