2-(3,4-Dimethoxyphenyl)ethanol
-
2-(3,4-Dimethoxyphenyl)ethanol
structure -
-
CAS No:
7417-21-2
-
Formula:
C10H14O3
-
Chemical Name:
2-(3,4-Dimethoxyphenyl)ethanol
-
Synonyms:
Benzeneethanol,3,4-dimethoxy-;Phenethyl alcohol,3,4-dimethoxy-;3,4-Dimethoxybenzeneethanol;3,4-Dimethoxyphenethanol;2-(3,4-Dimethoxyphenyl)ethanol;3,4-Dimethoxyphenethyl alcohol;3,4-Dimethoxy-β-phenethyl alcohol;1-(2-Hydroxyethyl)-3,4-dimethoxybenzene;Homoveratryl alcohol;AF 821;NSC 101852;NSC 179202;1,2-Dimethoxy-4-(2-hydroxyethyl)benzene;2-(3,4-Dimethoxyphenyl)ethan-1-ol
- Categories:
-
CAS No:
2-(3,4-Dimethoxyphenyl)ethanol Basic Attributes
182.22
182.22
231-032-5
179202|101852
DTXSID80225138
2909499000
Characteristics
38.7
1
Colorless Liquid/white powder.
1.1403 g/cm3 @ Temp: 20 °C
47-48 °C
140-150 °C @ Press: 0.1 Torr
127.6±23.2 °C
1.516
Keep container closed when not in use. Store in a cool, dry, well-ventilated area away from incompatible substances.
Safety Information
NONH for all modes of transport
3
R36/37/38
S22-S24/25
Xi
Stable under normal temperatures and pressures.
P264, P280, P305+P351+P338, P33, P313
H319
|Warning|H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]|P264, P280, P305+P351+P338, and P337+P313|Aggregated GHS information provided by 68 companies from 4 notifications to the ECHA C&L Inventory.
2-(3,4-Dimethoxyphenyl)ethanol Use and Manufacturing
Take a dry and clean 100 mL round bottom flask, accurately weigh sodium borohydride (0.4 g, 7.65 mmol) and iodine (1.3 g, 5.10 mmol) in a bottle, add 10 mL of tetrahydrofuran, place in an ice bath, stir After 5 min, 21 (1.0 g, 5.10 mmol) was added in small portions. After the addition, the ice bath was removed and the reaction was carried out at room temperature. The reaction was monitored by TLC. After 30 min, the reaction was completed by TLC. 50 ml of a 5percent sodium hydroxide solution was added to the reaction mixture, and the mixture was extracted with ethyl acetate (10 mL × 3), and the organic phase was combined and washed with brine (10 mL × 3). The organic phase was separated, dried over anhydrous sodium sulfate, filtered and evaporatedThe title compound (22) was obtained as a yellow oil.The yield was 98.9percent.General procedure: The system (Figure 4) was primed with solvent (DCM and 0.3 M aqueous NaOH) prior to the introduction of the substrates. Substrates were present as 0.034 M solutions (20 mL) in glass vials. These were placed in a square 4 x 4 rack. Following initiation of the computer-vision system (and checking to make sure the aqueous-out tap was opening/closing properly), activation of the autosampler/liquid-handling schedule was initiated by pressing ‘s’ on the computer keyboard. The outlet of the flow stream for each product was then collected until the autosampler moved to the waste position between each run. 5 mL of substrate was taken up during each run, 4 mL of which entered the holding loop (the line between the autosampler and 3-way-valve 1 was 1 mL in volume). Outlet collection flasks were changed manually. The products were isolated by removing solvent under reduced pressure.Preparation of 2-(3.4-dimethoxyphenyl)ethanol (2) from 4-bromo-l , 2- dimethoxybenzene (1)Magnesium turnings (3.9 g, 0.160 mol, 1.0 equiv) and I
Computed Properties
Molecular Weight:182.22
XLogP3:1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:182.094294304
Monoisotopic Mass:182.094294304
Topological Polar Surface Area:38.7
Heavy Atom Count:13
Complexity:138
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Recommended Suppliers of 2-(3,4-Dimethoxyphenyl)ethanol
-
![China]()
CN
3 YRS
Business licensedTrader Supplier of api,Intermediates,Organic Chemistry,Inorganic Chemistry,Daily Chemicals,Cosmetic Raw Materals,CATALYST AND AUXILIARY,FLAVORS AND FRAGRANCES,Chemical Pesticides,ADDITIVEInquiryCAS No.: 7417-21-2Grade: Pharmaceutical GradeContent: 99% -
![China]()
CN
4 YRS
Business licensed Certified factoryManufactory Supplier of 5 Bromo 2 chloropyrimidineInquiryCAS No.: 7417-21-2Grade: Industrial GradeContent: 98% -
![China]()
CN
4 YRS
Business licensedTrader Supplier of Semaglutide,Tirzepatide,API,EnzymeMore than 15 years GMP Factory Suppy 99.5% 3,4-Dimethoxyphenethyl alcohol Medical Grade CAS7417-21-2InquiryCAS No.: 7417-21-2Grade: Pharmaceutical GradeContent: 99.5%
Learn More Other Chemicals
-
(3S)-1,2,3,4-Tetrahydro-6,7-dimethoxy-3-isoquinolinecarboxylic acid
103733-66-0
-
2-Methoxy-5-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
1083168-84-6
-
2-iodo-2,3-dihydroinden-1-one
113021-30-0
-
2,2-DIMETHYL-N-[3-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-PYRIDIN-2-YL]-PROPIONAMIDE Formula
532391-30-3
-
6-Methylbenzoxazole Formula
10531-80-3
-
Methyl N-formylanthranilate Formula
41270-80-8
-
1-(4-amino-3,5-dichlorophenyl)-2-(dimethylamino)ethanol Structure
4812-69-5
-
2,5-Dihydroxy-N-(2-hydroxyethyl)benzamide Structure
61969-53-7
-
What is Benzenemethanol, α-(aminomethyl)-4-(1-methylethyl)-
91339-24-1
-
What is 5-Hydroxy-2-iodobenzaldehyde
50765-11-2