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Home > Encyclopedia > 5-IODO-6-METHYLPYRIMIDIN-4-OL

5-IODO-6-METHYLPYRIMIDIN-4-OL

5-IODO-6-METHYLPYRIMIDIN-4-OL structure

5-IODO-6-METHYLPYRIMIDIN-4-OL 

structure
  • CAS No:

    7752-74-1

  • Formula:

    C5H5IN2O

  • Chemical Name:

    5-IODO-6-METHYLPYRIMIDIN-4-OL

  • Synonyms:

    5-iodo-6-methylpyrimidin-4-ol;5-Iodo-6-methylpyrimidin-4(1H)-one;4-hydroxy-5-iodo-6-methylpyrimidine;5-iodo-6-methyl-1H-pyrimidin-4-one;5-Iodo-6-methyl-3H-pyrimidin-4-one;4-Pyrimidinol, 5-iodo-6-methyl-;SCHEMBL503673;CTK7C3088;KS-00000RRK;DTXSID20346957

  • Categories:

    Pharmaceutical Intermediates  >  Heterocyclic Compound

5-IODO-6-METHYLPYRIMIDIN-4-OL Basic Attributes

236.01

235.945

DTXSID20346957

Characteristics

41.5

0.3

245.5°C at 760 mmHg

5-IODO-6-METHYLPYRIMIDIN-4-OL Use and Manufacturing

To 70 g (0.64 mol) A-1 in acetic acid is added 127 g (0.56 mol) NIS portion wise at RT within 15 min. The reaction is stirred at RT until all starting material is consumed (30 h). The reaction mixture is diluted with water and the solid product is filtered off, washed with an aqueous sodium thiosulfate solution to remove excess iodine and dried in vacuo. Yield: 90 g (60 percent).To 70 g (0.64 mol) A-1 in acetic acid is added 127 g (0.56 mol) NIS portion wise at RT within 15 min.

Computed Properties

Molecular Weight:236.01
XLogP3:0.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Exact Mass:235.94466
Monoisotopic Mass:235.94466
Topological Polar Surface Area:41.5
Heavy Atom Count:9
Complexity:207
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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