Stannous chloride

189.62

189.839905

231-868-0

0955

3260|1759

DTXSID8021351

White, ortho rhombic crystals|Orthorhombic crystalline mass or flakes; fatty appearance

2827399000

0

0.99820

White powder

3.90 g/cm³

246 °C

623 °C

652°C

soluble in water, alkalies, alcohol, methyl ethyl ketone, methyl acetate and acetone.

Store at RT.

3.3 kPa @ 427.9 deg C

LD50 in mice, rats (mg/kg): 1710.0, 2000.0 orally; 271.0, 316.0 i.p.; 34.8, 43.0 i.v. (Singh, Junnarkar)

Violent reactions with hydrogen peroxide; ethylene oxide; hydrazine hydrate; nitrates; /potassium/; /sodium/.

Odorless

Heat of fusion: 14.52 kJ/mol|Density: 2.71; mp: 37-38 °C when rapidly heated; decomp on strong heating; sol in less than its own wt of water; very sol in dil or concn hydrochloric acid; sol in alc, ethyl acetate, glacial acetic acid, sodium hydroxide; absorbs oxygen from air and forms insol oxychloride /dihydrate/

Water soluble.

Salts, Acidic

Strong Reducing Agent

STANNOUS CHLORIDE is a powerful reducing agent. Can react violently with oxidizing agents. Undergoes flaming reaction with bromine trifluoride [Mellor 2 Supp. 1:164 1956]. Catalyzes the exothermic rearrangement and polymerization of ethylene oxide [J. Soc. Chem. Ind. 68:179 1949]. Mixtures with calcium carbide can be ignited with a match, and the reaction proceeds with incandescence [Mellor 7:430 1946-47]. Reacts with hydrazine hydrate to give stannous dihydrazine chloride which decomposes explosively when heated [Mellor 7:430 1946-47]. Undergoes a strongly exothermic reaction with aqueous solutions of hydrogen peroxide having concentration exceeding 3%) [Chem. & Ind., 1949, 657].

II

8

UN 3260 8/PG 3

1

22-34-36/37/38-37-68-50/53-48/22-43-20-63

26-36/37/39-45-61-60-53

XP8700000

C,Xi,N

Separated from incompatible materials and food and feedstuffs. Dry.

Stable, but moisture sensitive. Incompatible with strong bases, strong oxidizing agents, reactive metals, hydrogen peroxide, water.

P260-P280-P303 + P361 + P353-P304 + P340 + P310-P305 + P351 + P338

H314-H317-H332-H335-H341-H361-H373-H410

SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.

Hydrazine hydrate reacts with stannous chloride to give ... stannous dihydrazinechloride. When this compound is heated, it decomposes explosively.|Bromine trifluoride & stannous chloride react with flame.|A mixture of /stannous chloride & nitrates/ ... may cause an explosion.|A mixture of sodium & /stannous chloride/ ... produces a strong explosion on impact. ...|For more Hazardous Reactivities and Incompatibilities (Complete) data for STANNOUS CHLORIDE (9 total), please visit the HSDB record page.

Stannous chloride is a food additive permitted for direct addition to food for human consumption, as long as 1) the quantity of the substance added to food does not exceed the amount reasonably required to accomplish its intended physical, nutritive, or other technical effect in food, and 2) any substance intended for use in or on food is of appropriate food grade and is prepared and handled as a food ingredient.|Substance added directly to human food affirmed as generally recognized as safe (GRAS).|Stannous chloride used as a chemical preservative in animal drugs, feeds, and related products is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

DHHS/NTP; Toxicology & Carcinogenesis Studies of Stannous Chloride in F344/N Rats and B6C3F1 Mice (Feed Study) Technical Report Series No. 231 (1982) NIH Publication No. 82-1787|DHHS/ATSDR; Toxicological Profile for Tin TP-91/27 (1992)

Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]: Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Some are oxidizers and may ignite combustibles (wood, paper, oil, clothing, etc.). Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. For electric vehicles or equipment, ERG Guide 147 (lithium ion batteries) or ERG Guide 138 (sodium batteries) should also be consulted. (ERG, 2016)|Not combustible. Gives off irritating or toxic fumes (or gases) in a fire.

|Danger|H290 (23.18%): May be corrosive to metals [Warning Corrosive to Metals]|P234, P260, P261, P264, P270, P271, P272, P273, P280, P301+P312, P301+P330+P331, P302+P352, P303+P361+P353, P304+P312, P304+P340, P305+P351+P338, P310, P312, P314, P321, P322, P330, P333+P313, P337+P313, P363, P390, P391, P403+P233, P404, P405, and P501|Aggregated GHS information provided by 759 companies from 44 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.|H335: May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]|P260, P261, P264, P270, P271, P304+P340, P312, P314, P403+P233, P405, and P501|H303: May be harmful if swallowed [Warning Acute toxicity, oral]|P260, P261, P264, P270, P271, P280, P304+P340, P305+P351+P338, P312, P314, P337+P313, P403+P233, P405, and P501

Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]: SMALL FIRE: Dry chemical, CO2 or water spray. LARGE FIRE: Dry chemical, CO2, alcohol-resistant foam or water spray. Move containers from fire area if you can do it without risk. Dike fire-control water for later disposal; do not scatter the material. FIRE INVOLVING TANKS OR CAR/TRAILER LOADS: Fight fire from maximum distance or use unmanned hose holders or monitor nozzles. Do not get water inside containers. Cool containers with flooding quantities of water until well after fire is out. Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank. ALWAYS stay away from tanks engulfed in fire. (ERG, 2016)|In case of fire in the surroundings, use appropriate extinguishing media. In case of fire: keep drums, etc., cool by spraying with water.

Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]: As an immediate precautionary measure, isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids. SPILL: Increase, in the downwind direction, as necessary, the isolation distance shown above. FIRE: If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2016)

Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]: ELIMINATE all ignition sources (no smoking, flares, sparks or flames in immediate area). Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Stop leak if you can do it without risk. Prevent entry into waterways, sewers, basements or confined areas. Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers. DO NOT GET WATER INSIDE CONTAINERS. (ERG, 2016)

Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]: Wear positive pressure self-contained breathing apparatus (SCBA). Wear chemical protective clothing that is specifically recommended by the manufacturer. It may provide little or no thermal protection. Structural firefighters' protective clothing provides limited protection in fire situations ONLY; it is not effective in spill situations where direct contact with the substance is possible. (ERG, 2016)|Employees should be provided with and required to use impervious clothing, gloves, face shields (eight inch minimum), and other appropriate protective clothing necessary to prevent any possibility of skin contact with stannous chloride or liquids containing stannous chloride.|Employees should be provided with and required to use dust and splash proof goggles where stannous chloride or liquids containing stannous chloride may contact the eyes.

Ignition on contact with bromine trifluoride.

Potentially explosive reaction with metal nitrates.|Violent reactions with hydrogen peroxide; ethylene oxide; hydrazine hydrate; nitrates; /potassium/; /sodium/.

If ... stannous chloride ... is spilled or leaked, the following steps should be taken: 1. Ventilate area of spill or leak. 2. Collect spilled or leaked material in the most convenient and safe manner for reclamation or for disposal. ... Liquid containing inorganic tin compounds should be absorbed in vermiculite, dry sand, earth, or a similar material.

If employees' clothing may have become contaminated with solid stannous chloride ... employees should change into uncontaminated clothing before leaving the work premises. ... Non-impervious clothing which becomes wet with stannous chloride should be removed promptly and not reworn until the stannous chloride is removed from the clothing.|Clothing contaminated with stannous chloride /or/ stannic chloride ... should be placed in closed containers for storage until it can be discarded or until provision is made for the removal of contaiminant from the clothing. If the clothing is to be laundered or otherwise cleaned to remove the contaminant, the person performing the operation should be informed of contaminant's hazardous properties.|Skin that becomes contaminated with stannous chloride should be promptly washed to remove any stannous chloride. Employees who handle stannous chloride, stannic chloride ... should wash their hands thoroughly before eating, smoking, or using toilet facilities.|SRP: Contaminated protective clothing should be segregated in such a manner so that there is no direct personal contact by personnel who handle, dispose, or clean the clothing. Quality assurance to ascertain the completeness of the cleaning procedures should be implemented before the decontaminated protective clothing is returned for reuse by the workers. All contaminated clothing should not be taken home at end of shift, but should remain at employee's place of work for cleaning.|SRP: The scientific literature for the use of contact lenses in industry is conflicting. The benefit or detrimental effects of wearing contact lenses depend not only upon the substance, but also on factors including the form of the substance, characteristics and duration of the exposure, the uses of other eye protection equipment, and the hygiene of the lenses. However, there may be individual substances whose irritating or corrosive properties are such that the wearing of contact lenses would be harmful to the eye. In those specific cases, contact lenses should not be worn. In any event, the usual eye protection equipment should be worn even when contact lenses are in place.

Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. Carefully collect remainder. Then store and dispose of according to local regulations.

Separated from incompatible materials and food and feedstuffs. Dry.

A harmful concentration of airborne particles can be reached quickly when dispersed.

The substance is irritating to the eyes and respiratory tract.

Use local exhaust or breathing protection.

Protective gloves.

Wear safety goggles or eye protection in combination with breathing protection.

LD50 Mouse oral 1200 mg/kg|LD50 Mouse intraperitoneal 41 mg/kg|LD100 Mouse intraperitoneal 66 mg/kg|LD50 Rat oral 700 mg/kg|For more Non-Human Toxicity Values (Complete) data for STANNOUS CHLORIDE (9 total), please visit the HSDB record page.

... The chronic phase of a carcinogenesis bioassay for stannous chloride was conducted by feeding diets containing 1,000 or 2,000 ppm stannous chloride to groups of 50 F344/N rats and 50 B6C3F1/N mice of each sex for 105 wk. Similar groups of untreated rats and mice served as controls. Under the conditions of this bioassay, stannous chloride was judged not to be carcinogenic for male or female F344/N rats or B6C3F1/N mice, although C-cell tumors of the thyroid gland in male rats may have been associated with the admin of the test chemical. Levels of Evidence of Carcinogenicity: Male Rats: Equivocal; Female Rats: Negative;Male Mice: Negative; Female Mice: Negative.

Skin disease: Certain inorganic tin cmpd other than oxides are primary skin irritants. Persons with existing skin disorders may be more susceptible to the effects of these agents.

The concn of tin in the diaphysis was higher than in the epiphysis both in controls and rats given oral doses of stannous chloride for 28 days.|The effect of dietary tin on zinc, copper, & iron utilization by rats was studied. Male weanling Sprague-Dawley rats were fed a diet containing 206 ug tin (as stannous chloride)/g feed for 21 days. The rats fed the test diet lost more zinc in feces and retained much lower levels of zinc in tibias and kidneys than rats fed the control diet 1 ug tin/g. Rats fed the tin supplemented diet retained higher levels of tin in kidneys and tibias and lower levels of copper in kidneys than controls.|Volunteers in a balance experiment given diets containing 0.11 or 49.67 mg tin (as stannous chloride) daily for 20 days appeared to absorb 50 and 3% of the tin, respectively, as estimated from dietary and fecal tin recovery.|... Rats and rabbits absorbed <2% of orally administered tin from stannous chloride.

Absorbs oxygen from air and forms insol oxychloride /dihydrate/

Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]: TOXIC; inhalation, ingestion or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution. (ERG, 2016)|Corrosives

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop. SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment. INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing. INGESTION: DO NOT INDUCE VOMITING. Corrosive chemicals will destroy the membranes of the mouth, throat, and esophagus and, in addition, have a high risk of being aspirated into the victim's lungs during vomiting which increases the medical problems. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. IMMEDIATELY transport the victim to a hospital. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. Transport the victim IMMEDIATELY to a hospital. (NTP, 1992)

Fresh air, rest.

Remove contaminated clothes. Rinse skin with plenty of water or shower.

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

In this study tin(II), as stannous chloride, is readily taken up by human white blood cells and can cause damage to DNA. Damage was detected in white blood cells after exposure to 10-50 uM tin(II) for 30 minutes at either 0 deg or 37 °C.|Organotin compounds examined in this study exhibited a relative order of potency for induction of in vitro hemolysis in human erythrocytes as follows: tri-n-butylitin > tri-n-propyltitn > tetra-n-butyltin > triphenyltin chloride > tri-n-ethyltin bromide > dibutyltin dichloride > stannous chloride > tri-n-methyltin chloride + butyltin chloride dihydroxide.

SnCl(2)

The substance can be absorbed into the body by inhalation of its aerosol and by ingestion.

Cough. Sore throat.

Redness. Pain.

Stannous chloride is available in 2 forms: anhydrous and stannous chloride dihydrate, also called tin crystals or tin salts.|Grades: technical; chemically pure; reagent. ...|Anhydrous, 99.5% reagent and 99% technical grades. ...

All other basic inorganic chemical manufacturing|Tin chloride (SnCl2): ACTIVE

Health Hazards -> Corrosives|Cosmetics -> Reducing

Food Additives -> ANTIOXIDANT; COLOUR_RETENTION_AGENT;