10-[2-(Dimethylamino)propyl]-N,N-dimethyl-10H-phenothiazine-2-sulfonamide
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![10-[2-(Dimethylamino)propyl]-N,N-dimethyl-10H-phenothiazine-2-sulfonamide structure](https://file.echemi.com/fileManage/upload/canonicalSmiles/20220812/a763a53d29d145f79825bfb8c085bca7.png "10-[2-(Dimethylamino)propyl]-N,N-dimethyl-10H-phenothiazine-2-sulfonamide")
10-[2-(Dimethylamino)propyl]-N,N-dimethyl-10H-phenothiazine-2-sulfonamide
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CAS No:
7456-24-8
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Formula:
C19H25N3O2S2
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Chemical Name:
10-[2-(Dimethylamino)propyl]-N,N-dimethyl-10H-phenothiazine-2-sulfonamide
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Synonyms:
10H-Phenothiazine-2-sulfonamide,10-[2-(dimethylamino)propyl]-N,N-dimethyl-;Phenothiazine-2-sulfonamide,10-[2-(dimethylamino)propyl]-N,N-dimethyl-;10-[2-(Dimethylamino)propyl]-N,N-dimethyl-10H-phenothiazine-2-sulfonamide;10-[2-(Dimethylamino)propyl]-N,N-dimethylphenothiazine-2-sulfonamide;Dimethothiazine;Dimetotiazine;Fonazine;Dimethiotazine
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CAS No:
Description
Dimetotiazine is a member of phenothiazines.|Dimetotiazine has considerable antiemetic & serotonin antagonistic action used mainly in allergic skin conditions.
10-[2-(Dimethylamino)propyl]-N,N-dimethyl-10H-phenothiazine-2-sulfonamide Basic Attributes
391.557
391.55
231-229-6
DTXSID6023076
N - Nervous system
Drug Information
Drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine. Included here are the classical antihistaminics that antagonize or prevent the action of histamine mainly in immediate hypersensitivity. They act in the bronchi, capillaries, and some other smooth muscles, and are used to prevent or allay motion sickness, seasonal rhinitis, and allergic dermatitis and to induce somnolence. The effects of blocking central nervous system H1 receptors are not as well understood. (See all compounds classified as Histamine H1 Antagonists.)
10-(2-(dimethylamino)propyl)-N,N-dimethylphenothiazine-2-sulfonamide monomethane sulfonate
10-[2-(Dimethylamino)propyl]-N,N-dimethyl-10H-phenothiazine-2-sulfonamide Use and Manufacturing
Serotonin inhibitor.
Computed Properties
Molecular Weight:391.6
XLogP3:3.8
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:5
Exact Mass:391.13881940
Monoisotopic Mass:391.13881940
Topological Polar Surface Area:77.5
Heavy Atom Count:26
Complexity:576
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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10-[2-(Dimethylamino)propyl]-N,N-dimethyl-10H-phenothiazine-2-sulfonamide
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