Triamcinolone hexacetonide
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Triamcinolone hexacetonide
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CAS No:
5611-51-8
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Formula:
C30H41FO7
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Chemical Name:
Triamcinolone hexacetonide
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Synonyms:
Pregna-1,4-diene-3,20-dione,21-(3,3-dimethyl-1-oxobutoxy)-9-fluoro-11-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]-,(11β,16α)-;Pregna-1,4-diene-3,20-dione,9-fluoro-11β,16α,17,21-tetrahydroxy-,cyclic 16,17-acetal with acetone,21-(3,3-dimethylbutyrate);Butyric acid,3,3-dimethyl-,21-ester with 9-fluoro-11β,16α,17,21-tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with acetone;(11β,16α)-21-(3,3-Dimethyl-1-oxobutoxy)-9-fluoro-11-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione;CL 34433;Aristospan;TATBA;Triamcinolone hexacetonide;Triamcinolone acetonide 21-tert-butylacetate;Lederspan;Hexatrione;Lederlon;Triamcinolone acetonide tert-butyl acetate
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CAS No:
Description
Triamcinolone hexacetonide is a commonly used long-acting steroids in treatment of subacute and chronic inflammatory joint diseases.
Triamcinolone hexacetonide is a corticosteroid hormone.|Triamcinolone Hexacetonide is the hexacetonide salt form of triamcinolone, a synthetic glucocorticosteroid with immunosuppressive and anti-inflammatory activity. Triamcinolone hexacetonide binds to specific cytosolic glucocorticoid receptors and subsequently interacts with glucocorticoid receptor response element on DNA and alters gene expression. This results in an induction of the synthesis of certain anti-inflammatory proteins while inhibiting the synthesis of certain inflammatory mediators. Consequently, an overall reduction in chronic inflammation and autoimmune reactions are accomplished.
Triamcinolone hexacetonide Basic Attributes
532.64100
532.64
227-031-4
I7GT1U99Y9
DTXSID0048634
C48026
2937220000
Safety Information
NONH for all modes of transport
3
P201, P202, P260, P261, P263, P264, P270, P271, P272, P280, P281, P285, P301+P312, P302+P352, P304+P312, P304+P340, P304+P341, P308+P313, P312, P321, P322, P330, P333+P313, P342+P311, P363, P403+P233, P405, P501
H302
|Danger|H302 (75%): Harmful if swallowed [Warning Acute toxicity, oral]|P201, P202, P260, P261, P264, P270, P271, P272, P280, P281, P285, P301+P312, P302+P352, P304+P312, P304+P340, P304+P341, P308+P313, P312, P314, P321, P322, P330, P333+P313, P342+P311, P363, P405, and P501|Aggregated GHS information provided by 4 companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Drug Information
Substances that reduce or suppress INFLAMMATION. (See all compounds classified as Anti-Inflammatory Agents.)
9-fluoro-11 beta,16 alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with acetone, 21-(3,3-dimethylbutyrate)
Triamcinolone hexacetonide Use and Manufacturing
Triamcinolone Hexacetonide is the Intra-articular glucocorticoid treatment for rheumatoid arthritis.
Human Drugs -> FDA Approved Drug Products with Therapeutic Equivalence Evaluations (Orange Book) -> Active Ingredients|Pharmaceuticals
Computed Properties
Molecular Weight:532.6
XLogP3:4.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:6
Exact Mass:532.28363180
Monoisotopic Mass:532.28363180
Topological Polar Surface Area:99.1
Heavy Atom Count:38
Complexity:1130
Defined Atom Stereocenter Count:8
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Learn More Other Chemicals
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14,15-Dehydro Triamcinolone Acetonide
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6,7-Dehydro Triamcinolone Acetonide
1893-84-1
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Triamcinolone furetonide
4989-94-0
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Triamcinolone diacetate Formula
67-78-7
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Econazole nitrate mixture with triamcinolone acetonide Formula
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Triamcinolone benetonide Formula
31002-79-6
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Triamcinolone acetonide Structure
76-25-5
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Triamcinolone Structure
124-94-7