Iophendylate

416.33700

416.34

202-787-8

DTXSID2052869

COLORLESS TO PALE YELLOW, VISCOUS LIQUID

V - Various

2916399090

26.30000

6.07860

1.261g/cm3

<25 °C

421.2ºC at 760mmHg

208.5ºC

1.526

FREELY SOL IN ALCOHOL, BENZENE, CHLOROFORM, ETHER; VERY SLIGHTLY SOL IN WATER

LD50 in mice, rats (g/kg): 4.6, 19 i.p. (Steinhausen)

ODORLESS OR FAINTLY ETHEREAL ODOR

SAPONIFICATION EQUIV 395-420

DARKENS SLOWLY IN AIR

Contrast Media|IT IS ABSORBABLE, IODIZED FATTY ACID COMPD OF LOW VISCOSITY DESIGNED ESPECIALLY FOR MYELOGRAPHY. ... IT IS EQUALLY USEFUL FOR VISUALIZATION OF ALL REGIONS OF SPINAL CORD, ALTHOUGH THIS MAY BE TECHNICALLY MORE DIFFICULT IN CERVICAL & THORACIC REGIONS. ... IOPHENDYLATE ALSO IS USED IN EMULSIFIED AQUEOUS FORM AS CONTRAST MEDIUM FOR VISUALIZATION OF BILIARY TREE, SINUS TRACTS, & CERTAIN BODY CAVITIES.|IT IS COMMONLY USED FOR VISUALIZATION OF TUMORS OR HERNIATION OF INTERVERTEBRAL DISC OR OTHER LESIONS COMPRESSING SPINAL CORD.|VET: TO OUTLINE SALIVARY GLANDS, DRAINING SINUSES, OR FISTULAS; IT MAY BE SAFE (1-3 ML) IN SPINAL VENTRICULOGRAPHY OF DOGS.|DOSE- USUAL, MYELOGRAPHY, INTRATHECAL OR BY SPECIAL INJECTION

THIS AGENT SHOULD NOT BE USED INTRAVASCULARLY. ... AGENT SHOULD NOT BE USED WHEN LUMBAR PUNCTURE IS CONTRAINDICATED; &, TO AVOID SUBDURAL & EXTRA-ARACHNOID EXTRAVASATION, IT SHOULD NOT BE EMPLOYED WITHIN 10 DAYS OF PREVIOUS LUMBAR PUNCTURE.|...PERSISTENT LEVELS IN BODY INTERFERE WITH TRACER STUDIES WITH RADIOACTIVE IODINE.|WHEN BULK OF MATERIAL IS REMOVED...INCIDENCE OF SIDE REACTIONS IS LOW.|IN GENERAL, IODINATED CONTRAST MEDIA SHOULD BE ADMINISTERED WITH CAUTION IN PATIENTS WITH HEPATIC OR RENAL DYSFUNCTION. ... THE INJECTION OF IODIZED FATTY ACIDS IS ESSENTIALLY A SURGICAL PROCEDURE THAT INVOLVES RISK. THE FOLLOWING CAUTIONS SHOULD BE BORNE IN MIND. PREPARATIONS THAT HAVE AGED & DARKENED BEYOND THE ORIGINAL COLOR SHOULD NOT BE USED. ... THE COMPOUNDS SHOULD NOT BE ADMINISTERED TO INDIVIDUALS WITH HISTORY OF SENSITIVITY TO IODIDES. /IODINATED CONTRAST MEDIA/|For more Drug Warnings (Complete) data for IOPHENDYLATE (6 total), please visit the HSDB record page.

Substances used to allow enhanced visualization of tissues. (See all compounds classified as Contrast Media.)

WHEN EXAM IS COMPLETED, COMPD SHOULD BE REMOVED BY ASPIRATION. WHEN BULK OF MATERIAL IS REMOVED, REMAINDER IS ABSORBED WITHIN FEW MONTHS...

BULLOUS ERUPTIONS OCCURRED AFTER IOPHENDYLATE MYELOGRAPHY.|A 56-YR-OLD MAN DEVELOPED EOSINOPHILIC MENINGITIS FOLLOWING MYELOGRAPHY WITH IOPHENDYLATE.|A 30-YR-OLD WOMAN WITH HISTORY OF CERVICAL MYELOGRAM USING IOPHENDYLATE DEVELOPED FOCAL EPILEPTIC SEIZURES 4 MO LATER. RADIOLOGY & COMPUTERIZED TOMOGRAPHY REVEALED PRESENCE OF RETAINED CONTRAST MEDIA.|TWO UNUSUAL CASES OF CONSTRICTIVE ARACHNOIDITIS LOCALIZED TO THORACIC LEVELS AFTER PANTOPAQUE MYELOGRAPHY ARE PRESENTED.|For more Human Toxicity Excerpts (Complete) data for IOPHENDYLATE (7 total), please visit the HSDB record page.

Ethiodan

IOPHENDYLATE INJECTION, USP (PANTOPAQUE) IS MIXTURE OF ISOMERS OF ETHYL IODOPHENYLUNDECANOATE, CONSISTING OF ETHYL 10-(IODOPHENYL)UNDECANOATE. DOSAGE FORMS: INJECTION (STERILE IOPHENDYLATE): 1, 3, 6, & 12 ML.|VET: CONTAINS 30.5% IODINE.

IT WAS SUGGESTED THAT A 0.22 UM MILLIPORE FILTER BE USED TO SCREEN OFF THE GLASS PARTICLES THAT FALL INTO THE OILY MEDIUM WHEN GLASS AMPULS OF IOPHENDYLATE (PANTOPAQUE) ARE OPENED.