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CATALASE

CATALASE structure

CAS No:
9001-05-2
Formula:
C9H10O3
Chemical Name:
CATALASE
Synonyms:
equilase;Catalase-Agarose;Catalase from A. niger, lyophil.;Catalase from bovine liver, lyophil.;Catalase-peroxidase;CATALASE FROM BOVINE LIVERCA.65000 U/MG PROTEIN SUSPENSION;CATALASE FROM ASPERGILLUSNIGER CA.2000 U/MG LYOPH.SALT-FREE;CATALASE FROM BOVINE LIVERCA. 11000 U/MG LYOPH. SALTFREE
Categories:
Food Additives > Enzyme

Description

Catalase is a key enzyme in the metabolism of H2O2 and reactive oxygen species (ROS), and its expression and localization is markedly altered in tumors[1]. Free oxygen radical scavenger.

Almost all biological organisms have catalase. It is common in breathing organisms, mainly in the plants' chloroplasts, mitochondria, endoplasmic reticulum, animal liver and red blood cells.Its enzymatic activity provides antioxidant defense mechanism to the body.CAT is a red blood hormone enzyme. Different sources have different structures.The level of activity is different in different tissues.Hydrogen peroxide decomposes faster in the liver than in brain or heart organs, which is due to the high levels of CAT in the liver.

brown crystalline solid

ChEBI: Ethylparaben is an ethyl ester resulting from the formal condensation of the carboxy group of 4-hydroxybenzoic acid with ethanol, It has a role as an antimicrobial food preservative, an antifungal agent, a plant metabolite and a phytoestrogen. It is a paraben and an ethyl ester.

CAT (catalase) is an endogenous antioxidant enzyme, thus conferring protection to cells against damage by ROS (reactive oxygen species). In humans, this gene is localized to chromosome 11p13, which is composed of 12 introns and 13 exons.

CATALASE Basic Attributes

Molecular Weight：

166.1739

Exact Mass：

166.062988

EC Number：

232-577-1

TSCA：

TSCA listed

Color/Form：

deep brown

HScode：

35079090

Characteristics

PSA：

46.5

XLogP3：

2.47

Appearance：

deep brown suspension

Density：

1.06 g/mL at 20 °C

Melting Point：

116 °C

Boiling Point：

297-298 deg C (decomposition)

Flash Point：

41 °C

Refractive Index：

1.539

Water Solubility：

125g/L at 25℃

Storage Conditions：

2-8°C

Vapor Pressure：

0Pa at 25℃

Flammability characteristics：

Thermal decomposition emits spicy and irritating smoke

Odor：

Odorless

PH：

5.4(isoelectric point)

Critical Temperature & Pressure：

-20°C

Safety Information

Transport codes：

UN 1993 3/PG 3

wgk germany：

hazard class code：

safety instructions：

23-24/25-22

RTECS Number：

FI4378000

Marks：

Storage features：

The warehouse is low-temperature, ventilated and dry

Stability/Shelf Life：

Air and moisture sensitive. Incompatible with strong oxidizing agents. Refrigerate.

Precautionary statement(s)：

P261, P264, P271, P272, P280, P301+P310, P302+P352, P304+P340, P305+P351+P338, P312, P321, P331, P332+P313, P333+P313, P337+P313, P362, P363, P403+P233, P405, P501

Hazard Statements：

RIDADR：

UN 1993 3/PG 3

CATALASE Use and Manufacturing

Methods of Manufacturing

It is purified from bovine liver extract. It is derived from Aspergillus niger var. culture under controlled conditions such as ventilation and stirring. It is extracted and refined from the deep fermentation broth of Micrococcus lysodeikticus.

Uses

In combination with glucose oxidase, for treatment of food wrappers to prevent oxidative deterioration of food:Sarett, Scott, US 2765233 (1956 to Ben L. Sarett).In the removal of traces of peroxide in the process of cold sterilization (preservation of milk and cheese by treatment with hydrogen peroxide).With glucose oxidase, q.v., in food preservation.

Catalase from Sigma has been used as a positive control during the functional characterization ofClostridium difficilespore coat proteins.

Catalase agarose has been used in a study to advance the treatment of oxidative stress in neurodegenerative diseases. Catalase agarose has also been used in a study to investigate the growth of cyanobacterium on agar media in the presence of heterotrophic bacteria.

Material

Ammonium sulfate

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