Polyethylene glycol lauryl ether
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Polyethylene glycol lauryl ether
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CAS No:
9002-92-0
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Formula:
(C2H4O)nC12H26O
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Chemical Name:
Polyethylene glycol lauryl ether
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Synonyms:
Poly(oxy-1,2-ethanediyl),α-dodecyl-ω-hydroxy-;Glycols,polyethylene,monododecyl ether;Dodecyl alcohol,monoether with polyethylene glycol;Atlas G 2133;Atlas G 3705;Cimagel;Lanettes;Laureth 9;G 2130A;Simulol 330M;LA;Pegnol L 12;Poly(oxyethylene) dodecyl ether;Lauryl polyethylene glycol ether;Polyethylene glycol lauryl ether;Poly(oxyethylene) lauryl ether;Brij 30;Brij 35;Hydroxypolyethoxydodecane;Polyethylene glycol monolauryl ether;Polyethylene glycol dodecyl ether;Thesat;Poly(ethylene oxide) dodecyl ether;Polyoxyethylene lauryl alcohol ether;Dodecyl poly(oxyethylene) ether;Ethylene oxide-lauryl alcohol polycondensate;LA 7;Polyethylene glycol monododecyl ether;Oxyethylenated dodecyl alcohol;Romopal LN;Texofor B 9;Thesit;Do 9;Mergital LM 11;Noigen ET 170;Polyethoxylated dodecanol;Base LP 12;G 3707;Lauryl poly(oxyethylene) ether;Aldosperse L 9;Noigen ET 160;Lubrol PX;Poly(oxyethylene) monolauryl ether;Poly(oxyethylene) monododecyl ether;Ethoxylated lauryl alcohol;Marlipal 1217;Ethosperse LA 4;Ethosperse LA 23;α-Dodecyl-ω-hydroxypoly(oxyethylene);Lauromacrogol 400;Lipal 4LA;Chimipal AE 3;Nikkol BL 25;Emulgen 120;Emulgen 109;Laureth 12;Lipocol L 12;Lipocol L 4;LA (alcohol);Laureth 23;Siponic L 3;BL 9;Ethosperse LA 12;Rokanol L 10;Rokanol L 2;Rokanol L 4;Rokanol L 6;Rokanol L;Emulgen 147;Polidocanol;Ethylene oxide-lauryl alcohol adduct;Emulgen 108;Polyoxyethylene dodecyl alcohol ether;1334-72-1;1341-05-5;6540-99-4;8027-11-0;9015-55-8;9079-21-4;11106-34-6;14675-38-8;31798-98-8;37231-23-5;37343-87-6;39316-02-4;39316-41-1;39363-77-4;50815-85-5;50815-86-6;51426-13-2;53026-66-7;53241-34-2;54351-54-1;54398-17-3;55599-84-3;55892-94-9;56093-86-8;56590-57-9;56939-70-9;57244-90-3;61373-94-2;61710-38-1;62229-27-0;64772-19-6;66048-74-6;69344-85-0;71636-71-0;71932-08-6;86547-02-6;86727-31-3;87296-34-2;101008-55-3;101840-74-8;102329-60-2;102342-03-0;106254-08-4;106254-09-5;106856-65-9
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CAS No:
Description
Polidocanol is a sclerosing agent used successfully to treat extremity and esophageal varices and telangiectasias.
Characteristics
232.52000
log Kow = 3.40 (est)
Liquid
1.03
48 °C
100ºC(lit.)
74.9ºC
n20/D 1.461
soluble
Store at RT.
<1 mm Hg ( 20 °C)
LD50 in mice (mg/kg): 1170 orally, 125 i.v. (Zipf)
PLEASANT
Safety Information
UN 1993 3/PG 3
3
R22; R36/37/38
S26-S37/39
EJ6229000
Xn
Stable. Combustible. Incompatible with strong oxidizing agents.
P280-P305 + P351 + P338
H302-H315-H318
Polyethylene glycol lauryl ether Use and Manufacturing
Polidocanol is a local anaesthetic and antipruritic component of ointments and bath additives. It relieves itching caused by eczema and dry skin. It is formed by the ethoxylation of dodecanol.The substance is also used as a sclerosant, an irritant injected to treat varicose veins, under the trade names Asclera, Aethoxysklerol and Varithena. Polidocanol causes fibrosis inside varicose veins, occluding the lumen of the vessel, and reducing the appearance of the varicosity.The FDA has approved polidocanol injections for the treatment of small varicose (less than 1mm in diameter) and reticular veins (1 to 3mm in diameter). Polidocanol works by damaging the cell lining of blood vessels, causing them to close and eventually be replaced by other types of tissue.Pure polidocanol for pharmaceutical use
Drug Function and Efficacy
Extract from the above information
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