Tricine
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Tricine
structure -
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CAS No:
5704-04-1
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Formula:
C6H13NO5
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Chemical Name:
Tricine
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Synonyms:
Glycine,N-[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]-;N-[2-Hydroxy-1,1-bis(hydroxymethyl)ethyl]glycine;Tricine;N-[Tris(hydroxymethyl)methyl]glycine;NSC 369995;2-[[1,3-Dihydroxy-2-(hydroxymethyl)propan-2-yl]amino]acetic acid;1644287-59-1
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CAS No:
Description
White/clear crystalline powder
N-tris(hydroxymethyl)methylglycine is a Good's buffer substance, pKa = 8.15 at 20 ℃. It derives from a member of tris and a glycine. It is a tautomer of a N-tris(hydroxymethyl)methylammonioacetate.
Characteristics
110.02000
-5.1
white crystalline powder
1.05g/mLat20ºC
187 °C
500.9ºC at 760 mmHg
256.7ºC
1.553
H2O: soluble
Store at RT.
Safety Information
NONH for all modes of transport
3
R36/37/38
S26-S36/37/39
Xi
Stable.
P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, P501
H315
Not Classified
Tricine Use and Manufacturing
Tricine is an organic compound that is used in buffer solutions. The name tricine comes from tris and glycine, from which it was derived. It is a white crystalline powder that is moderately soluble in water. It is a zwitterionic amino acid that has apKa1 value of 2.3at 25 °C, while itspKa2at 20 °C is 8.15. Its useful buffering range of pH is 7.4-8.8. Along with bicine, it is one of Good's buffering agents. Good first prepared tricine to buffer chloroplast reactions.
Glycine, N-[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]-: ACTIVE
Computed Properties
Molecular Weight:179.17
XLogP3:-5.1
Hydrogen Bond Donor Count:5
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:6
Exact Mass:179.07937252
Monoisotopic Mass:179.07937252
Topological Polar Surface Area:110
Heavy Atom Count:12
Complexity:137
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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