2,4,5-Trichloropyrimidine
-
2,4,5-Trichloropyrimidine
structure -
-
CAS No:
5750-76-5
-
Formula:
C4HCl3N2
-
Chemical Name:
2,4,5-Trichloropyrimidine
-
Synonyms:
2,5,6-TRICHLOROPYRIMIDINE;2,4,5-TRICHLOROPYRIMIDINE;2,4,5-Trichloro-1,3-diazine;Pyrimidine, 2,4,5-trichloro-;2,4,5-three chloropyriMidine;2,4,5-TrichloropyriMidine 99%;2,4,5-Trichloropyrimidine ,98%;2,4,5-Trichloropyrimidine, 99+%;2,4,5-TRICHLOROPYRIMIDINE, 97+%;Two, four, five - cheMical pyriMidine
- Categories:
-
CAS No:
2,4,5-Trichloropyrimidine Basic Attributes
183.42
181.920532
4449
1312995-182-4
40593
DTXSID50206116
2933599090
Characteristics
25.8
2.8
Colorless to pale yellow liquid
1.6001 g/mL at 25 °C(lit.)
84°C1mm
>230 °F
n20/D 1.574(lit.)
Not miscible or difficult to mix in water.
Safety Information
III
8
3267
3
36/37/38
26-36
Xi
Irritant
P261-P305 + P351 + P338
H315-H319-H335
|Danger|H314 (11.54%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]|P260, P261, P264, P271, P280, P301+P330+P331, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P310, P312, P321, P332+P313, P337+P313, P362, P363, P403+P233, P405, and P501|Aggregated GHS information provided by 52 companies from 8 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
2,4,5-Trichloropyrimidine Use and Manufacturing
5-Chlorouracil (4.5 g, 30.82 mmol) was dissolved in phosphorus oxychloride (100 mL) and phosphorus pentachloride (19.2 g, 92.46 mmol) was added. The reaction mixture was heated at reflux overnight; it was then cooled to RT and the solvent was evaporated under reduced pressure. The residue was cooled to 0 compound 1 Example 10 N-(2-(2, 5 -dichloropyrimidin-4-ylamino)phenyl)-cyclopropanecarboxamide; A 500 mL round bottomed flask was charged with 5-chlorouracil a (25.0 g, 170 mmol, 1.0 equiv) and phosphoryl chloride (159 mL, 1.7 mol, 10 equiv). The reaction vessel was equipped with a vigoreaux column followed by careful addition of diisopropylethylamine (59 mL, 340 mmol, 2.0 equiv) over 1 minute. Evolution of white fumes was observed during the addition of diisopropylethylamine. The reaction was then heated to 110 Method 19 Method 3 Method 5 Method 8 Method 11 3A Preparation of 2, 4, 5-trichloropyrimidine
Computed Properties
Molecular Weight:183.42
XLogP3:2.8
Hydrogen Bond Acceptor Count:2
Exact Mass:181.920531
Monoisotopic Mass:181.920531
Topological Polar Surface Area:25.8
Heavy Atom Count:9
Complexity:99.8
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Recommended Suppliers of 2,4,5-Trichloropyrimidine
-
![China]()
CN
4 YRS
Business licensedTrader Supplier of Fluorine containing fine chemicals Pharmaceutical -
![China]()
CN
8 YRS
Business licensed Certified factoryManufactory Supplier of Biochemicals Ingredients,Vitamin Amino Acid Ingredients,Cosmestic Ingredients,Pharma Chemicals,Organic Fine Chemicals,Food Nutrient Ingredients,Natural Plant Ingredients,APIS Intermidiates,Daily Chemicals,Agricultural Chemicals,Surfactant Chemicals,Ultraviolet Absorbents,Antioxidant Ingredients,Scientific Research Chemical,Flavors and Fragrances ChemicalsInquiryCAS No.: 5750-76-5Grade: Pharmaceutical GradeContent: 99%
Learn More Other Chemicals
-
(2E)-3-(1-METHYL-1H-PYRROL-2-YL)ACRYLIC ACID
51485-76-8
-
Benadryl N-oxide hydrochloride
13168-00-8
-
6-CHLORO-3-IODO-IMIDAZO[1,2-A]PYRIDINE
885275-59-2
-
(2-Bromophenyl)diphenylphosphine Formula
62336-24-7
-
1-Morpholinocyclopentene Formula
936-52-7
-
4-[2-(Boc-amino)ethoxy]-benzoic acid Formula
168892-66-8
-
3-amino-5-bromopyridine-2-carboxylic acid Structure
870997-85-6
-
2-Amino-6-methylpyridine Structure
1824-81-3
-
What is 3-Bromo-2-methylthiophene
30319-05-2
-
What is THIOPHEN-2-YLMETHYL-PHOSPHONICACIDDIETHYLESTER
2026-42-8