2-Aminoanthracene

193.24

193.24

2209414

210-330-9

8240818JGU

400535

DTXSID2024458

Yellow leaflets from alcohol

2921499090

26

3.40

2-aminoanthracene appears as yellow to brownish-yellow powder or solid. (NTP, 1992)

1.2±0.1 g/cm3

238-241 °C

199° F at 9 mm Hg (sublimes) (NTP, 1992)

229.0±15.4 °C

1.766

Slightly sol in ether

Peritoneal-mouse LD50: 1500 mg/kg

Flammable; burning produces toxic nitrogen oxide fumes

Sublimes|UV: 6851 (Sadtler Research Laboratories Spectral Collection) /1-Aminoanthracenamine/|UV: 5-400 (Organic Electronic Spectral Data, Phillips et al, John Wiley & Sons, New York) /9-Aminoanthracenamine/

Insoluble in water.

Hydrocarbons, Aromatic

2-AMINOANTHRACENE may be unstable with prolonged exposure to air and light. Solutions of this chemical should be stable for 24 hours under normal lab conditions. (NTP, 1992)

NONH for all modes of transport

3

36/37/38

26-24/25

CA9275000

Xi

Warehouse ventilated, low temperature and dry

Stable. Incompatible with strong oxidizing agents.

P261-P305 + P351 + P338

H315-H319-H335

SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.|The following wastewater treatment technologies have been investigated for 2-anthracenamine: Biological treatment and solvent extraction.

Flash point data for this chemical are not available; however, it is probably combustible. (NTP, 1992)

|Warning|H315 (90.7%): Causes skin irritation [Warning Skin corrosion/irritation]|P201, P202, P261, P264, P271, P280, P281, P302+P352, P304+P340, P305+P351+P338, P308+P313, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 43 companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)

SMALL SPILLS AND LEAKAGE: If a spill of this chemical occurs, FIRST REMOVE ALL SOURCES OF IGNITION, then you should dampen the solid spill material with acetone and transfer the dampened material to a suitable container. Use absorbent paper dampened with acetone to pick up any remaining material. Seal your contaminated clothing and the adsorbent paper in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with acetone followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned. STORAGE PRECAUTIONS: You should protect this chemical from exposure to light. Keep the container tightly closed under an inert atmosphere, and store under refrigerated temperatures. (NTP, 1992)

RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter. (NTP, 1992)

SRP: The scientific literature for the use of contact lenses in industry is conflicting. The benefit or detrimental effects of wearing contact lenses depend not only upon the substance, but also on factors including the form of the substance, characteristics and duration of the exposure, the uses of other eye protection equipment, and the hygiene of the lenses. However, there may be individual substances whose irritating or corrosive properties are such that the wearing of contact lenses would be harmful to the eye. In those specific cases, contact lenses should not be worn. In any event, the usual eye protection equipment should be worn even when contact lenses are in place.

moderately toxic

2-Anthracenamine has been identified as a constituent of synfuel(1).|FORMED FROM INCOMPLETE COMBUSTION OF ORGANIC MATERIALS (EG, REFUSE BURNING, OPERATION OF MOTOR VEHICLES, INDUST PROCESSES)

TERRESTRIAL FATE: If released to soil, 2-anthracenamine is expected to be immobilized by strong adsorption to soil. This compound would probably photolyze on soil surfaces. Volatilization and hydrolysis are not expected to be environmentally important fate processes. Insufficient data are available to predict the significance of biodegradation. (SRC)|AQUATIC FATE: If released to water, 2-anthracenamine may adsorb strongly to suspended solids and sediments, bioaccumlate significantly in aquatic organisms or photolyze rapidly in near-surface waters (estimated midday, midsummer photolysis half-life less than 4.5 days). Chemical hydrolysis is not expected to be an environmentally significant process. Insufficient data are available to predict the significance of biodegradation. (SRC)|ATMOSPHERIC FATE: If released to the atmosphere, 2-anthracenamine is expected to exist both in the vapor phase and adsorbed to particulate matter(1,SRC). This compound may react with photochemically generated hydroxyl radicals in the atmosphere (estimated vapor phase half-life 1.8 hours(2,3,SRC)), it may undergo direct photolysis, or it may be subject to dry deposition(SRC). Adsorption of 2-anthracenamine onto particulate matter may retard direct photolysis and reaction with hydroxyl radicals(4,SRC).

The half-life for reaction of 2-anthracenamine vapor with photochemically generated hydroxyl radicals in air has been estimated to be 1.8 hours based on an estimated reaction rate constant of 2.2X10-10 cu cm/molecules-sec at 25 °C(1,SRC) and average ambient hydroxyl radical concentration of 5.0X10+5 molecules/cu cm(2). Polyaromatic hydrocarbons, in general, absorb UV light in the environmentally significant range (wavelengths greater than 290 nm) and are susceptible to direct photolysis in the environment(3). The occurrence of an amino group on the anthracene structure, is predicted to cause 2-anthracenamine to photolyze faster than anthracene which has an estimated near-surface photolysis half-life (latitude 40 deg N, midday, midsummer) of 4.5 days in water(3,SRC). 2-Anthracenamine contains no hydrolyzable functional groups, and therefore, is not expected to undergo hydrolysis in the environment(4,5,SRC).

A bioconcentration factor (BCF) of 3141 has been estimated for 2-anthracenamine using a linear regression equation based on a measured water solubility of 0.056 mg/l at 25 °C(1,2,SRC). This BCF value suggests that 2-anthracenamine bioaccumulates significantly in aquatic organisms(SRC).

2.82e+04 L/kg|Koc ranging between 94276 and 15904 were measured for 2-anthracenamine in fourteen different soils and sediments(1). These Koc are indicative of extremely strong adsorption to soil and suspended solids and sediments in water(2,SRC).

The Henry's Law constant for 2-anthracenamine has been estimated to be 3.0X10-7 atm-cu m/mol at 25 °C by combining a measured Henry's Law Constant for anthracene of 7.2X10-4 atm-cu m/mole at 25 °C(1) with an estimation method based on structural bond contributions to intrinsic hydrophilic character(2,SRC). Given this value of Henry's Law constant and the relatively high Koc (15904 to 94276(4)) of 2-anthracenamine, it appears as though volatilization would not be a significant removal process from soil or water(3,SRC). This is apparent from the result of an EXAMS run for a model pond in which the effects of adsorption were considered. In this case, the volatilization half-life was determined to be 98 years(5,SRC).

NIOSH (NOES Survey 1981-1983) has statistically estimated that 198 workers are exposed to 2-anthracenamine in the USA(1).

Substances that increase the risk of NEOPLASMS in humans or animals. Both genotoxic chemicals, which affect DNA directly, and nongenotoxic chemicals, which induce neoplasms by other mechanism, are included. (See all compounds classified as Carcinogens.)|Chemical agents that increase the rate of genetic mutation by interfering with the function of nucleic acids. A clastogen is a specific mutagen that causes breaks in chromosomes. (See all compounds classified as Mutagens.)

ACUTE/CHRONIC HAZARDS: When heated to decomposition this compound emits toxic fumes. (NTP, 1992)

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop. SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment. INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing. INGESTION: DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital. (NTP, 1992)

2-aminoanthracene