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UTP

pharmaceutical raw materials
UTP structure

UTP 

structure
  • CAS No:

    63-39-8

  • Formula:

    C9H15N2O15P3

  • Chemical Name:

    UTP

  • Synonyms:

    Uridine 5′-(tetrahydrogen triphosphate);Uridine 5′-triphosphate;UTP (nucleotide);Uridine triphosphate;Uridine,mono(tetrahydrogen triphosphate) (ester);Uteplex;5′-UTP;UTP;802560-63-0;1259312-97-4;1613528-29-2

  • Categories:

    Biochemical Engineering  >  Saccharides

Description

Uridine triphosphate (UTP;Uridine 5'-triphosphate) is a pyrimidine nucleoside triphosphate that participates in glycogen metabolism and synthesis of RNA during transcription.


Solid


UTP is a pyrimidine ribonucleoside 5'-triphosphate having uracil as the nucleobase. It has a role as an Escherichia coli metabolite and a mouse metabolite. It is a pyrimidine ribonucleoside 5'-triphosphate and a uridine 5'-phosphate. It is a conjugate acid of an UTP(4-) and an UTP(3-).|Uridine 5'-(tetrahydrogen triphosphate). A uracil nucleotide containing three phosphate groups esterified to the sugar moiety.|INS316 is a short-acting, aerosolized uridine 5-triphosphate (UTP) solution used as a diagnostic aid for lung cancer. INS316 appears to improve sputum expectoration mediated through the P2Y2 receptor, a nucleotide receptor expressed in human airway epithelial cells and some other tissues. UTP binding to the P2Y2 receptor triggers signal transduction that leads to chloride ion secretion, thereby resulting in mucociliary clearance of airway.

UTP Basic Attributes

484.14100

484.14

200-558-7

UT0S826Z60

DTXSID0041147

C2613

Characteristics

293.80000

-5.8

Solid

2.106 g/cm3

113ºC

-20ºC

178.55 Ų [M-H]- [CCS Type: DT, Method: single field calibrated with Agilent tune mix (Agilent)]|187 Ų [M+H]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|188.8 Ų [M+Na]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|180.1 Ų [M-H]- [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|180.2 Ų [M-H]- [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|190.2 Ų [M+Na-2H]- [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]

Safety Information

1

R20/21/22

22-26-36

Xn

P264, P280, P302+P352, P305+P351+P338, P321, P332+P313, P337+P313, P362

H315

Drug Information

Magnesium Uridine Triphosphate

Computed Properties

Molecular Weight:484.14
XLogP3:-5.8
Hydrogen Bond Donor Count:7
Hydrogen Bond Acceptor Count:15
Rotatable Bond Count:8
Exact Mass:483.96852877
Monoisotopic Mass:483.96852877
Topological Polar Surface Area:259
Heavy Atom Count:29
Complexity:839
Defined Atom Stereocenter Count:4
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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