 Home > Encyclopedia > Dibenz[b,f]azepine

Dibenz[b,f]azepine

Dibenz[b,f]azepine structure

CAS No:
256-96-2
Formula:
C14H11N
Chemical Name:
Dibenz[b,f]azepine
Synonyms:
5H-Dibenz[b,f]azepine;5-Azadibenzo[a,e]cycloheptatriene;2,2′-Iminostilbene;Stilbene,2,2′-imino-;Iminostilbene;Dibenzazepine;Dibenz[b,f]azepine;5H-Dibenzo[b,f]azepine;RP 9989;NSC 123458;2295813-03-3
Categories:
Pharmaceutical Intermediates > Heterocyclic Compound

Description

Iminostilbene is a a chemical precursor of carbamazepine[1].

5H-dibenzo[b,f]azepine is a mancude organic heterotricyclic parent that consists of a seven-membered nitrogen hetrocycle fused with two benzene rings. It has a role as a marine xenobiotic metabolite. It is a mancude organic heterotricyclic parent and a dibenzoazepine.

Dibenz[b,f]azepine Basic Attributes

Molecular Weight：

193.24

Exact Mass：

193.24

BRN：

1343358

EC Number：

249-478-4

UNII：

J411KQJ8C2

NSC Number：

123458

DSSTox ID：

DTXSID6040458

ATC Code：

N03AF01

HScode：

2933990090

Characteristics

PSA：

XLogP3：

Appearance：

yellow to orange powder

Density：

1.1±0.1 g/cm3

Melting Point：

198 °C

Boiling Point：

150-180 °C @ Press: 0.1 Torr

Flash Point：

>230 °F

Refractive Index：

1.627

Water Solubility：

soluble in ethyl acetate (25 mg/ml), water (partly), dioxane, chloroform, and DMSO.dioxane: 50 mg/mL, clear

Storage Conditions：

Refrigerator

Vapor Pressure：

4.81E-05mmHg at 25°C

Safety Information

Transport codes：

UN 3265 8/PG 2

wgk germany：

hazard class code：

34-51/53-22-36/37/38

safety instructions：

26-36/37/39-45-61-27-24/25

Marks：

C,Xi,N,Xn

Hazard note：

Irritant

Stability/Shelf Life：

Stable under normal temperatures and pressures.

Precautionary statement(s)：

P273

Hazard Statements：

H302-H411

Drug Information

Drug Transformations：

Iminostilbene is a known transformation product of Carbamazepine.

MeSH：

Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. (See all compounds classified as Enzyme Inhibitors.)

MeSH Entry Terms：

dibenzazepine

Dibenz[b,f]azepine Use and Manufacturing

Methods of Manufacturing

By 10.11 dihydro-5H-diphenyl [b, f] aza [494-19-9] by elimination.

Uses

A metabolite of Carbamazepine (CBZ) (C175840).

Use Classification：

Pharmaceuticals -> Nervous System -> Antiepileptics -> Carboxamide derivatives -> Transformation products

Computed Properties

Molecular Weight:193.24
XLogP3:4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Exact Mass:193.089149355
Monoisotopic Mass:193.089149355
Topological Polar Surface Area:12
Heavy Atom Count:15
Complexity:222
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Recommended Suppliers of Dibenz[b,f]azepine

Hangzhou KieRay Chem Co.,LTD Contact Supplier

CN
5 YRS

Business licensed Certified factory

Manufactory Supplier of fine chemicals,pharmaceutical materials

Iminostilbene

CAS No.: 256-96-2

Grade: industrial Grade

Content: 98%

Inquiry
HANGZHOU LEAP CHEM CO., LTD. Contact Supplier

CN
5 YRS

Business licensed

Trader Supplier of Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals,Biochemicals,Pharmaceuticals,Screening Compounds,Food Additives

Iminostilbene

CAS No.: 256-96-2

Content: 99.00%

Inquiry
Zhejiang ZETian Fine Chemicals Co., Ltd. Contact Supplier

CN
5 YRS

Business licensed

Distributor Supplier of Inorganic Chemicals,Organic Chemicals,Chemical Raw Material,Pharmaceutical Intermediate

Iminostilbene

CAS No.: 256-96-2

Grade: Pharmaceutical Grade

Content: 99%

Inquiry
Henan Lihao Chem Plant Limited Contact Supplier

CN
5 YRS

Business licensed

Trader Supplier of PVC resin,pvc paste resin,melamine

high quality Iminostilbene 99% transparent liquid KANBEI

CAS No.: 256-96-2

Grade: Industrial Grade

Content: 99%

Inquiry
Hangzhou Chungyo Chemicals Co., Ltd. Contact Supplier

CN
3 YRS

Business licensed Certified factory

Manufactory Supplier of Dyes,Textile agent,Medical intermediate,API,Pigments,Basic Chemicals

Iminostilbene

CAS No.: 256-96-2

Grade: pharmaceutical grade

Content: 99%

Inquiry