 Home > Encyclopedia > Oxytetracycline hydrochloride

Oxytetracycline hydrochloride

Oxytetracycline hydrochloride structure

CAS No:
2058-46-0
Formula:
C22H24N2O9.ClH
Chemical Name:
Oxytetracycline hydrochloride
Synonyms:
2-Naphthacenecarboxamide,4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-,hydrochloride (1:1),(4S,4aR,5S,5aR,6S,12aS)-;2-Naphthacenecarboxamide,4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-,monohydrochloride;2-Naphthacenecarboxamide,4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-,monohydrochloride,[4S-(4α,4aα,5α,5aα,6β,12aα)]-;2-Naphthacenecarboxamide,4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-,monohydrochloride,(4S,4aR,5S,5aR,6S,12aS)-;1-Dimethylamino-1,4,6,11,12,13,14,18-octahydro-2,5,7,11,12,14-hexahydroxy-4,6-dioxo-11-methylnaphthacene-3-carbonamide hydrochloride;Liquamycin Injectable;Oxytetracycline hydrochloride;Terramycin hydrochloride;Tetran hydrochloride;5-Hydroxytetracycline hydrochloride;TM 5;5-Hydroxytetracycline monohydrochloride;Aquacycline;Engemycin;Oxytetrin;Mepatar;Oxytet;Oxylag;Gynamousse;Oxybiocycline;Oxycyclin;Occrycetin;Terraject;Oxyject;Oxy-Dumocyclin;Oxypan;Toxinal;Duphacycline;Oxytetracid;Oxy WS;Tetramel;Oxlopar;Alamycin;Oxybiotic;Tetra-Tabilinen;Biocyl;Maxicyklin;Vetilmicin;Teramycin;Terramycin 343;61794-35-2;72034-96-9;90438-85-0;102323-64-8;885678-73-9;1231953-59-5
Categories:
Active Pharmaceutical Ingredients > Antibiotics

Request for Quotation

Description

Yellow Crystalline Solid

Oxytetracycline hydrochloride Basic Attributes

Molecular Weight：

496.89

Exact Mass：

532.101563

EC Number：

218-161-2

HScode：

29413000

Characteristics

PSA：

201.85000

XLogP3：

0.25870

Appearance：

yellow crystalline

Density：

1.71 g/cm3

Melting Point：

178 °C (decomp)

Boiling Point：

839.6ºC at 760 mmHg

Flash Point：

461.6ºC

Water Solubility：

H2O: >100 g/L;soluble in ethanol

Storage Conditions：

0-6°C

Vapor Pressure：

2.17E-30mmHg at 25°C

Toxicity：

LD50 oral in mouse: 6696mg/kg

Safety Information

Hazard category：

Transport codes：

UN 3077 9/PG III

wgk germany：

hazard class code：

63-36-36/37/38

safety instructions：

36/37/39-26-36-36/37

RTECS Number：

QI8225000

Marks：

Xn,Xi

Stability/Shelf Life：

Stable at room temperature in closed containers under normal storage and handling conditions.

Precautionary statement(s)：

P281

Hazard Statements：

H361d

Oxytetracycline hydrochloride Use and Manufacturing

Oxytetracycline hydrochloride is a salt prepared from oxytetracycline taking advantage of the basic dimethylamino group which protonates readily to form the salt in hydrochloric acid solutions. The hydrochloride is the preferred formulation for pharmaceutical applications. Like all tetracyclines, oxytetracycline shows broad spectrum antibacterial and antiprotozoan activity and acts by binding to the 30S and 50S ribosomal sub-units, blocking protein synthesis.

Material

Activated charcoal

Hydrochloric acid

Sulfuric acid

Price Analysis

Make your Oxytetracycline hydrochloride purchase based on the price and market insights! ECHEMI provides professional market insights with prices for you to make a better choice. Learn more on Oxytetracycline hydrochloride prices .

Drug Function and Efficacy

Tetracycline antibiotics. This product is a broad-spectrum antibacterial agent. Many Rickettsia, Mycoplasma, Chlamydia, Spirochete, Amoeba and some Plasmodium are also sensitive to this product. Enterococcus is resistant to it. Others such as Actinomycetes, Bacillus anthracis, Listeria monocytogenes, Clostridium, Nocardia, Vibrio, Brucella, Campylobacter, Yersinia, etc. are sensitive to this product. This product has certain antibacterial activity against gonococci and meningococci, but penicillin-resistant gonococci are also resistant to oxytetracycline. Due to the widespread use of tetracyclines over the years, common clinical pathogens have serious resistance to oxytetracycline, including Gram-positive bacteria such as Staphylococcus and most Gram-negative bacteria. There is cross-resistance between different varieties of tetracycline antibiotics.

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Oxytetracycline Hydrochloride Capsules
Specifications	0.25g (calculated as C22H24N209)
Manufacturer	China Resources 39 (Beijing) Pharmaceutical Co., Ltd.

Oxytetracycline Hydrochloride Tablets
Ingredients	The main ingredient of this product is oxytetracycline hydrochloride, and its chemical name is 6-methyl-4-(dimethylamino)-3,5,6,10,12,12a-hexahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydro-2-naphthacenecarboxamide hydrochloride.
Indication	1 When used with antacids such as sodium bicarbonate, the absorption of this product may be reduced and its activity may be reduced due to the increase in gastric pH. Therefore, antacids should not be taken within 1 to 3 hours after taking this product. 2 Drugs containing metal ions such as calcium, magnesium, and iron may form insoluble complexes with this product, reducing the absorption of this product after oral administration. 3 When used in combination with the general anesthetic methoxyflurane, its nephrotoxicity may be enhanced. 4 When used in combination with strong diuretics such as furosemide, renal damage may be aggravated. 5 When used in combination with other hepatotoxic drugs (such as anti-tumor chemotherapy drugs), liver damage may be aggravated. 6 The lipid-lowering drugs colestyramine or colestipol may affect the absorption of this product.
Specifications	Calculated as C22H24N2O9 0.25g
Manufacturer	Jilin Yinnuoke Pharmaceutical Co., Ltd.

Oxytetracycline Hydrochloride Tablets
Ingredients	The main ingredient of this product is oxytetracycline hydrochloride, and its chemical name is 6-methyl-4-(dimethylamino)-3,5,6,10,12,12a-hexahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydro-2-naphthacenecarboxamide hydrochloride.
Indication	1 When used with antacids such as sodium bicarbonate, the absorption of this product may be reduced and its activity may be reduced due to the increase in gastric pH. Therefore, antacids should not be taken within 1 to 3 hours after taking this product. 2 Drugs containing metal ions such as calcium, magnesium, and iron may form insoluble complexes with this product, reducing the absorption of this product after oral administration. 3 When used in combination with the general anesthetic methoxyflurane, its nephrotoxicity may be enhanced. 4 When used in combination with strong diuretics such as furosemide, renal damage may be aggravated. 5 When used in combination with other hepatotoxic drugs (such as anti-tumor chemotherapy drugs), liver damage may be aggravated. 6 The lipid-lowering drugs colestyramine or colestipol may affect the absorption of this product.
Specifications	0.25g (calculated as C22H24N209)
Manufacturer	Diaoyutai Pharmaceutical Group Jilin Changqing Pharmaceutical Co., Ltd.

See More Related Drugs

Registered Holders

CENTURY PHARMACEUTICALS LTD

United States
Active
Chifeng Pharmaceutical Co.,Ltd.

Japan
Active
Shijiazhuang Huashu Zhongkang Pharmaceutical Co., Ltd.

China
Active

See More Registered Holders

Recommended Suppliers of Oxytetracycline hydrochloride

Hangzhou Dawn Ray Pharmaceutical Co.,Ltd Contact Supplier

CN
5 YRS

Business licensed Certified factory

Manufactory Supplier of D-Biotin,Tobramycin base,L(-)-Carnitine base,Polymyxin B sulfate USP,Kanamycin sulfate monohydrate,Finasteride 99% USP

Oxytetracycline hydrochloride (cas:2058-46-0)

CAS No.: 2058-46-0

Inquiry
SHANDONG LOOK CHEMICAL CO.,LTD Contact Supplier

CN
5 YRS

Business licensed Certified factory

Manufactory Supplier of Agrochemicals,Daily Chemicals,Catalysts & Chemical Auxiliary Agents,Extract,Inorganic Chemicals,Organic Intermediate,Pigment & Dyestuff,Polymer,Flavour & Fragrance,Basic Organic Chemicals,Pharmaceutical

Oxytetracycline Hydrochloride HCl

Unit Price: $17-18 /KG FOB

CAS No.: 2058-46-0

Grade: USP/EP Grade, Feed Grade / Pharma Grade

Inquiry
Henan Lihao Chem Plant Limited Contact Supplier

CN
5 YRS

Business licensed

Trader Supplier of PVC resin,pvc paste resin,melamine

high purity hot sale Oxytetracycline Hydrochloride 99% high quality see COA KANBEI

CAS No.: 2058-46-0

Grade: Industrial Grade

Content: 99%

Inquiry
Baoji Guokang Bio-Technology Co.,Ltd Contact Supplier

CN
9 YRS

Business licensed Certified factory

Manufactory Supplier

Oxytetracyclinehydrochloride

CAS No.: 2058-46-0

Grade: Medical Grade

Inquiry
Yiling Wanyang Import and Export Co.,ltd Contact Supplier

CN
10 YRS

Business licensed Certified factory

Manufactory Supplier of Aspirin,Salicylic Acid

Oxytetracycline hydrochloride

CAS No.: 2058-46-0

Grade: Pharmaceutical Grade

Content: 95%

Inquiry

Latest News on Oxytetracycline hydrochloride

Learn More Other Chemicals

4H-1-Benzopyran-4-one, 2-[4-[3-(dibutylamino)propoxy]-3,5-dimethylbenzoyl]-, hydrochloride (1:1)

67652-33-9
Cyclopropanecarboxylic acid, 1-amino-2-ethenyl-, ethyl ester, hydrochloride (9CI)

681807-60-3
CYCLOPENTYL-(3,4,5-TRIMETHOXY-BENZYL)-AMINE HYDROCHLORIDE

1052525-88-8
2-Cyclopropylbenzenemethanamine hydrochloride Formula

118184-64-8
Des[4-(2-cycloproylMethoxy)] Betaxolol Hydrochloride Formula

464877-45-0
Ethanamine, 2-(decylthio)-, hydrochloride (1:1) Formula

36362-09-1
4,7-Dichloro-2-propylquinoline hydrochloride Structure

1204812-22-5
6,7-Dichloro-4-hydrazino-2-methylquinoline hydrochloride Structure

1170377-12-4
What is 2,8-Diazaspiro[4.5]decan-1-one, 2-[(4-bromophenyl)methyl]-, hydrochloride (1:1)

832710-56-2
What is 6,7-Dichloro-4-hydrazinoquinoline hydrochloride

1171843-02-9

Hot Searches: formalin; calcium bicarbonate; pseudomembranous colitis; propylene carbonate; nocl; lead oxide

Guide of Oxytetracycline hydrochloride

Description
Basic Attributes
Characteristics
Safety Information
Use and Manufacturing
Material
Price Analysis
Drug Function and Efficacy
Related Drugs
Registered Holders
Recommended Suppliers
Latest News
Learn More Other Chemicals

Oxytetracycline hydrochloride

SDS

Request for Quotation



Feedback & Suggestions

Send Message

Thank you for your feedback. If you require further assistance, please contact us by email at info@echemi.com or call us at +86-532-55729510.