1-Chlorooctane

148.674

148.67

203-915-5

E1047328LO

5406

DTXSID0021543

COLORLESS LIQUID

29031980

0

4.73

Liquid

0.8738 g/cm³ @ Temp: 20 °C

-57.8 °C

181.5 °C @ Press: 760 Torr

158 DEG F

n 20/D 1.430(lit.)

H2O: 0.02g/l;SOL IN MOST ORG SOLVENTS

Keep away from heat, sparks, and flame. Keep away from sources of ignition. Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

1 mm Hg ( 22.2 °C)

At standard state = -1269.3 kcal/mol at 25 °C, as a liquid.

12.73 kcal/mol at 25 °C

III

9

UN 1993 3/PG 3

2

R52/53

23-24/25-61-60-45-36/37/39-26-57

N,C

Stable under normal temperatures and pressures.

P273-P301 + P310-P331-P391-P501

H304-H410

SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.

|Danger|H304 (51.96%): May be fatal if swallowed and enters airways [Danger Aspiration hazard]|P273, P301+P310, P331, P391, P405, and P501|Aggregated GHS information provided by 179 companies from 8 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.|Warning|H227: Combustible liquid [Warning Flammable liquids]|P210, P273, P280, P370+P378, P391, P403+P235, and P501

1-Chlorooctane's production and use in the manufacture of organometallics, as a chemical intermediate(1), and as a stabilizer(2) may result in its release to the environment through various waste streams(SRC). 1-Chlorooctane is formed during the chlorination process in the treatment of drinking water(3).

TERRESTRIAL FATE: Based on a recommended classification scheme(1), an estimated Koc value of 8900(SRC), determined from a measured log Kow(2) and a recommended regression-derived equation(3), indicates that 1-chlorooctane will be immobile in soil(SRC). Volatilization of 1-chlorooctane may be important from moist soil surfaces(SRC) given an estimated Henry's Law constant of 6.0X10-2 atm-cu m/mole(SRC), using a fragment constant estimation method(4). The rate of this process may be attenuated based on the Koc value estimated for this compound(SRC). Volatilization from dry soil surfaces(SRC) is expected based on a measured vapor pressure of 0.95 mm Hg(5). Based on limited data, 1-chlorooctane is expected to readily biodegrade in soil under aerobic conditions(SRC). In an aerobic aqueous screening test, 1-chlorooctane, incubated with a sludge inoculum, reached 74-81% of the theoretical BOD in 4 weeks(6).|AQUATIC FATE: Based on a recommended classification scheme(1), an estimated Koc value of 4.73(SRC), determined from a measured log Kow(2,SRC) and a recommended regression-derived equation(1), indicates that 1-chlorooctane should adsorb to suspended solids and sediment in water(SRC). 1-Chlorooctane may volatilize from water surfaces(1,SRC) based on an estimated Henry's Law constant of 6.0X10-2 atm-cu m/mole(SRC), developed using a fragment constant estimation method(3). Estimated half-lives for a model river and model lake are 4 hours and 5 days, respectively(1,SRC). Adsorption to sediment and particulate matter may attenuate the rate of this process(SRC). According to a classification scheme(4), an estimated BCF value of 2300(1,SRC), from a measured log Kow(2), suggests that bioconcentration in aquatic organisms is very high(SRC). Based on limited data, 1-chlorooctane is expected to readily biodegrade in water under aerobic conditions(SRC). In an aerobic aqueous screening test, 1-chlorooctane, incubated with a sludge inoculum, reached 74-81% of the theoretical BOD in 4 weeks(5).|ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), 1-chlorooctane, which has a measured vapor pressure of 0.95 mm Hg at 25 °C(2), will exist solely as a vapor in the ambient atmosphere. Vapor-phase 1-chlorooctane is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be about 2 days(3,SRC).

The rate constant for the vapor-phase reaction of 1-chlorooctane with photochemically-produced hydroxyl radicals has been estimated as 7.8X10-12 cu cm/molecule-sec at 25 °C(SRC) using a structure estimation method(1,SRC). This corresponds to an atmospheric half-life of about 2 days at an atmospheric concentration of 5X10+5 hydroxyl radicals per cu cm(1,SRC).

An estimated BCF value of 2300 was calculated for 1-chlorooctane(SRC), using a measured log Kow of 4.73(1) and a recommended regression-derived equation(2). According to a classification scheme(3), this BCF value suggests that bioconcentration in aquatic organisms is very high(SRC).

The Koc of 1-chlorooctane is estimated as approximately 8900(SRC), using a measured log Kow of 4.73(1) and a regression-derived equation(2,SRC). According to a recommended classification scheme(3), this estimated Koc value suggests that 1-chlorooctane will be immobile in soil(SRC).

The Henry's Law constant for 1-chlorooctane is estimated as 6.0X10-2 atm-cu m/mole(SRC) using a fragment constant estimation method(1). This value indicates that 1-chlorooctane will volatilize rapidly from water surfaces(2,SRC). Based on this Henry's Law constant, the volatilization half-life from a model river (1 m deep, flowing 1 m/sec, wind velocity of 3 m/sec) is estimated as approximately 4 hours(2,SRC). The volatilization half-life from a model lake (1 m deep, flowing 0.05 m/sec, wind velocity of 0.5 m/sec) is estimated as approximately 5 days(2,SRC). The rate of this process may be attenuated somewhat by adsorption to suspended solids and sediment based on the Koc value estimated for this compound(SRC). 1-Chlorooctane's values for vapor pressure, 0.95 mm Hg(3) and Henry's Law constant(1,SRC) indicate that volatilization from dry and moist soil surfaces may occur(SRC).

SURFACE WATER: 1-Chlorooctane was detected in the water of the Black Warrior River in Tuscaloosa, AL at unreported concentrations(1).|DRINKING WATER: 1-Chlorooctane was detected in drinking water at an unreported location and concentration(1). Drinking water sampled from the District of Columbia water supply contained 1-chlorooctane at 0.001 ppm(2).

NIOSH (NOES Survey 1981-1983) has statistically estimated that 28 workers are potentially exposed to 1-chlorooctane in the USA(1). Occupational exposure may be through inhalation and dermal contact with this compound at workplaces where 1-chlorooctane is produced or used. The general population will be exposed to 1-chlorooctane via ingestion of drinking water and dermal contact with vapors, water, and other products containing 1-chlorooctane(SRC).

LIQUID FRACTIONS ARE...CENTRAL NERVOUS DEPRESSANTS WHEN ABSORBED FROM ALIMENTARY TRACT, OR SEVERE PULMONARY IRRITANTS WHEN ASPIRATED. /ALIPHATIC HYDROCARBONS/|LIQUIDS, AS FAT SOLVENTS, EXTRACT SEBUM FROM SKIN LEAVING DRY IRRITATED SURFACE PRONE TO CRACKING & BACTERIAL INFECTION. /ALIPHATIC HYDROCARBONS/|A. ACUTE POISONING: (FROM INHALATION OR INGESTION). NAUSEA, VOMITING, COUGH, & PULMONARY...EDEMA, BLOODY SPUTUM, & BRONCHIAL PNEUMONIA WITH FEVER & COUGH. PNEUMOTHORAX & EMPHYSEMA MAY COMPLICATE RECOVERY. /ALIPHATIC HYDROCARBONS/|IF LARGE AMT (OVER 1 ML/KG) IS INGESTED & RETAINED, SYMPTOMS...INCL...SLOW & SHALLOW RESPIRATION, UNCONSCIOUSNESS, & CONVULSIONS. VENTRICULAR FIBRILLATION CAN OCCUR AFTER INGESTION OR INHALATION. /ALIPHATIC HYDROCARBONS/|B. CHRONIC POISONING: (FROM INHALATION) DIZZINESS, WEAKNESS, WT LOSS, ANEMIA, NERVOUSNESS, PAINS IN LIMBS, PERIPHERAL NUMBNESS, & PARESTHESIAS. /ALIPHATIC HYDROCARBONS/

Commercial products have 95% C8 content.

All other basic organic chemical manufacturing|Octane, 1-chloro-: ACTIVE|CMPD CONTAINING THE MONO- OR DICHLOROHYDROCARBONS AS ACTIVE INGREDIENTS ARE EFFECTIVE IN CONTROLLING COCCIDIOSIS IN DOMESTIC FOWLS. THUS, 1-CHLOROOCTANE 70 AND SURFACTANTS 30 PARTS WERE MIXED TO GIVE AN EMULSION PREPN. PREPN WAS DILUTED TO 40-100-FOLD & APPLIED TO CHICKEN HOUSES.