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Tris(dimethylamino)phosphine

Tris(dimethylamino)phosphine structure

Tris(dimethylamino)phosphine 

structure
  • CAS No:

    1608-26-0

  • Formula:

    C6H18N3P

  • Chemical Name:

    Tris(dimethylamino)phosphine

  • Synonyms:

    Phosphorous triamide,N,N,N′,N′,N′′,N′′-hexamethyl-;Phosphorous triamide,hexamethyl-;N,N,N′,N′,N′′,N′′-Hexamethylphosphorous triamide;Hexametapil;Hexamethylphosphorous triamide;Tris(dimethylamino)phosphine;Hexamethyltriamidophosphite;Hexamethyltriaminophosphine;HMPT;Trisdimethylaminophosphorus;NSC 102707;65274-41-1;309958-62-1

  • Categories:

    Organic Chemistry  >  Phosphines

Tris(dimethylamino)phosphine Basic Attributes

163.2

163.20

906778

216-534-4

6072HG2UW4

102707

DTXSID6061816

29299000

Characteristics

23.31000

0.17

Clear colorless to slightly yellow Liquid

0.8964 g/cm3 @ Temp: 20 °C

-44 °C

49 °C @ Press: 11 Torr

73 °F

n20/D 1.463(lit.)

Solubility in water: reaction

Store at RT.

2.4mmHg at 25°C

Safety Information

III

3

UN 1993 3/PG 3

3

45-46-10-40-36/37/38

53-45-36/37/39-26-16-37/39-36

TH3390000

T,Xi,Xn,F

Irritant

Stable. Highly flammable - note low flash point. Incompatible with oxidizing agents.

P201-P308 + P313-P370 + P378-P403 + P235

H226-H340-H350

|Danger|H226 (100%): Flammable liquid and vapor [Warning Flammable liquids]|P201, P202, P210, P233, P240, P241, P242, P243, P280, P281, P303+P361+P353, P308+P313, P370+P378, P403+P235, P405, and P501|Aggregated GHS information provided by 48 companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Tris(dimethylamino)phosphine Use and Manufacturing

Methods of Manufacturing

Dissolve 137.3g (1.0mol) of phosphorus trichloride in 1.5L of anhydrous ether, stir, cool to 1-5℃, pass excess anhydrous dimethylamine gas, control the aeration rate, so that the reaction temperature does not exceed 15℃ , After aeration, leave it at room temperature overnight in a nitrogen atmosphere, filter out the dimethylamine hydrochloride, the filtrate is evaporated under reduced pressure to recover ether, to obtain 152-154g, oily hexamethylphosphoramidite, yield 94-95 %.

Uses

Reagent combination with CCl4 for the conversion of hydroxyl groups to the corresponding chlorides; hydroxyl group activation; dehydrations.

Phosphorous triamide, N,N,N',N',N'',N''-hexamethyl-: ACTIVE

Computed Properties

Molecular Weight:163.20
XLogP3:0.6
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:163.12383458
Monoisotopic Mass:163.12383458
Topological Polar Surface Area:9.7
Heavy Atom Count:10
Complexity:74
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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