 Home > Encyclopedia > Guanoxan

Guanoxan

Guanoxan structure

CAS No:
2165-19-7
Formula:
C10H13N3O2
Chemical Name:
Guanoxan
Synonyms:
Guanidine,N-[(2,3-dihydro-1,4-benzodioxin-2-yl)methyl]-;Guanidine,(1,4-benzodioxan-2-ylmethyl)-;Guanidine,[(2,3-dihydro-1,4-benzodioxin-2-yl)methyl]-;1,4-Benzodioxin,guanidine deriv.;N-[(2,3-Dihydro-1,4-benzodioxin-2-yl)methyl]guanidine;(1,4-Benzodioxan-2-ylmethyl)guanidine;2-(Guanidinomethyl)-1,4-benzodioxan;Guanoxan;Guanoxane;2-(2,3-Dihydro-1,4-benzodioxin-3-ylmethyl)guanidine;46416-31-3
Categories:
Active Pharmaceutical Ingredients > Circulatory System Drugs

Description

Guanoxan is a benzodioxine.|Guanoxan is an antihypertensive agent similar in its mechanism of action to guanethidine; may cause liver damage. Guanoxan was approved in the UK but was withdrawn from the market due to hepatotoxicity.

Guanoxan Basic Attributes

Molecular Weight：

207.233

Exact Mass：

207.23

DSSTox ID：

DTXSID3046166

ATC Code：

C - Cardiovascular system

Characteristics

PSA：

82.9

XLogP3：

1.50040

Density：

1.4g/cm3

Melting Point：

164-165 °C

Boiling Point：

389.9ºC at 760mmHg

Flash Point：

189.6ºC

Refractive Index：

1.639

Drug Information

MeSH Entry Terms：

guanoxan

Guanoxan Use and Manufacturing

Guanoxan is a sympatholytic drug related to Guanethidine (G815000). Guanoxan is used in the treatment of hypertension.

Computed Properties

Molecular Weight:207.23
XLogP3:0.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:207.100776666
Monoisotopic Mass:207.100776666
Topological Polar Surface Area:82.9
Heavy Atom Count:15
Complexity:241
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes