Ubiquinone 8
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Ubiquinone 8
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CAS No:
2394-68-5
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Formula:
C49H74O4
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Chemical Name:
Ubiquinone 8
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Synonyms:
2,5-Cyclohexadiene-1,4-dione,2,3-dimethoxy-5-methyl-6-[(2E,6E,10E,14E,18E,22E,26E)-3,7,11,15,19,23,27,31-octamethyl-2,6,10,14,18,22,26,30-dotriacontaoctaen-1-yl]-;p-Benzoquinone,2,3-dimethoxy-5-methyl-6-(3,7,11,15,19,23,27,31-octamethyl-2,6,10,14,18,22,26,30-dotriacontaoctaenyl)-;2,5-Cyclohexadiene-1,4-dione,2,3-dimethoxy-5-methyl-6-(3,7,11,15,19,23,27,31-octamethyl-2,6,10,14,18,22,26,30-dotriacontaoctaenyl)-,(all-E)-;2,5-Cyclohexadiene-1,4-dione,2,3-dimethoxy-5-methyl-6-[(2E,6E,10E,14E,18E,22E,26E)-3,7,11,15,19,23,27,31-octamethyl-2,6,10,14,18,22,26,30-dotriacontaoctaenyl]-;2,3-Dimethoxy-5-methyl-6-[(2E,6E,10E,14E,18E,22E,26E)-3,7,11,15,19,23,27,31-octamethyl-2,6,10,14,18,22,26,30-dotriacontaoctaen-1-yl]-2,5-cyclohexadiene-1,4-dione;Coenzyme Q8;Ubiquinone 40;Ubiquinone 8;Ubiquinone Q8;CoQ8;20304-10-3
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CAS No:
Description
ChEBI: A ubiquinone whose structure comprises a 2,3-dimethoxy-5-methylbenzoquinone nucleus (common to all ubiquinones) and a side chain of eight isoprenoid units.
Ubiquinone-8 is a ubiquinone whose structure comprises a 2,3-dimethoxy-5-methylbenzoquinone nucleus (common to all ubiquinones) and a side chain of eight isoprenoid units. It has a role as a biomarker.
Ubiquinone 8 Use and Manufacturing
An isoprenoid quinone that enhances nonspecific resistance to bacterial infections. It stimulates phagocytosis in macrophages by modulation of the kinetics of the Fc receptor. It serves as an electron carrier from the flavoprotein to the cytochrome complex in reconstituted proteoliposomes where cytochrome O complex function as an efficient ubiquinol-8 oxidase.
Lipids -> Prenol Lipids [PR] -> Quinones and hydroquinones [PR02] -> Ubiquinones [PR0201]
Computed Properties
Molecular Weight:727.1
XLogP3:15.7
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:25
Exact Mass:726.55871084
Monoisotopic Mass:726.55871084
Topological Polar Surface Area:52.6
Heavy Atom Count:53
Complexity:1520
Defined Bond Stereocenter Count:7
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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