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2-Methoxybenzamide

2-Methoxybenzamide structure

CAS No:
2439-77-2
Formula:
C8H9NO2
Chemical Name:
2-Methoxybenzamide
Synonyms:
Benzamide,2-methoxy-;o-Anisamide;Benzamide,o-methoxy-;2-Methoxybenzamide;o-Methoxybenzamide;Orthopramide;NSC 84232
Categories:
Pharmaceutical Intermediates > Heterocyclic Compound

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2-Methoxybenzamide Basic Attributes

Molecular Weight：

151.165

Exact Mass：

151.16

EC Number：

219-465-8

UNII：

WRY8DDN8YC

NSC Number：

84232

DSSTox ID：

DTXSID6022189

HScode：

2924299090

Characteristics

PSA：

52.3

XLogP3：

0.8

Density：

1.1±0.1 g/cm3

Melting Point：

127.5 °C

Boiling Point：

147-149 °C @ Press: 24 Torr

Flash Point：

155.7±18.9 °C

Refractive Index：

1.546

Water Solubility：

0.02 M

Toxicity：

LD50 ipr-rat: 450 mg/kg JPETAB 108,450,53

Safety Information

hazard class code：

R22

safety instructions：

S26-S36/37

RTECS Number：

CV5460000

Precautionary statement(s)：

P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, P501

Hazard Statements：

H302

GHS Classification：

|Warning|H302 (97.73%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 44 companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

2-Methoxybenzamide Use and Manufacturing

Unless otherwise specified, carboxylic acid (0.542 mmol), TCT (0.0400 g, 0.216 mmol) and K2CO3 (0.2247 g, 1.626 mmol) were mixed together and hand ground for one minute using porcelain mortar and pestle. After addition of ammonium thiocyanate (0.0495 g, 0.650 mmol), the mixture was ground manually for further five minute. During the grinding, THF (calculated to be less than 1 L/mg of solids) was added to aid homogeneous mixing. The crude material was then purified by short column chromatography (column diameter 1.5 cm, packed with 3-4 g silica gel ) using 40-50% ethyl acetate/hexane as an eluent.

Computed Properties

Molecular Weight:151.16
XLogP3:0.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:151.063328530
Monoisotopic Mass:151.063328530
Topological Polar Surface Area:52.3
Heavy Atom Count:11
Complexity:147
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Recommended Suppliers of 2-Methoxybenzamide

Shaanxi Dideu Medichem Co. Ltd Contact Supplier

CN
4 YRS

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Manufactory Supplier of Chemical Pesticides,Food Additives,Agrochemicals,Active Pharm Ingredients,Flavors and Fragrances,Chemical Catalyst,Chemical Materials,Chem&Pharm Intermediates,Organic Intermediates,Feed Additive

2-Methoxybenzamide/

CAS No.: 2439-77-2

Grade: Pharmaceutical Grade

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Hangzhou Chungyo Chemicals Co., Ltd. Contact Supplier

CN
3 YRS

Business licensed Certified factory

Manufactory Supplier of Dyes,Textile agent,Medical intermediate,API,Pigments,Basic Chemicals

2-methoxy-benzamid

CAS No.: 2439-77-2

Grade: pharmaceutical grade

Content: 98%

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