2-Isopropyl-6-methyl-4-pyrimidinol

152.19

152.19

220-561-7

0JET159MZQ

DTXSID1027502

2933599090

41.5

0.50

BEIGE NEEDLES

1.1±0.1 g/cm3

170-172 °C

244.3±20.0 °C at 760 mmHg

101.6±21.8 °C

1.528

0.0655mmHg at 25°C

NONH for all modes of transport

2

36/37/38

26-37/39

UW7525000

Xi

P261-P305 + P351 + P338

H315-H319-H335

|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 38 companies from 1 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

A RADIOACTIVE HYDROLYSIS PRODUCT, 2-ISOPROPYL -4-METHYL-6-HYDROXYPYRIMIDINE WAS EXTRACTED FROM SOIL TREATED WITH DIAZINON. GREATER AMOUNTS OF THE HYDROLYSIS COMPOUNDS WERE RECOVERED FROM FUMIGATED SOIL IN WHICH THE MICROBIAL ACTIVITY WAS REDUCED, THAN FROM NON-FUMIGATED SOIL.

1.82

THERE WAS APPRECIABLE UPTAKE OF RADIOCARBON BY PANAGRELLUS REDIVIVUS, A FREE-LIVING SOIL NEMATODE; AND BURSAPHELENCHUS XYLOPHILUS, A PLANT PARASITIC NEMATODE, WHEN EXPOSED TO A SOLUTION OF (14)C-LABELED DIAZINON. METABOLITES FROM BURSAPHELENCHUS XYLOPHILUS INLUDED PYRIMIDINOL. ELIMINATION OF RADIOCARBON WAS MORE RAPID WITH PANAGRELLUS REDIVIVUS THAN WITH BURSAPHELENCHUS XYLOPHILUS, & THIS RESULTED IN THE PRESENCE OF HIGH LEVELS OF THE POLAR PYRIMIDINOL METABOLITE IN THE INCUBATION MEDIUM OF PANAGRELLUS REDIVIVUS.|Pyrimidinol is a known human metabolite of Diazinon and Diazoxon.

G 27550

4(3H)-Pyrimidinone, 6-methyl-2-(1-methylethyl)-: INACTIVE

AFTER SUBLIMATION BY HEATING AT 115 °FOR 10 MIN, PURIFIED 2-ISOPROPYL-6-METHYL-4-PYRIMIDINOL SHOWED A 99.25% RECOVERY IN SAMPLES NOT LESS THAN OR EQUAL TO 100 MUG. ANALYSIS WAS BY UV SPECTROPHOTOMETRY.|METHODS TESTED FOR USE AS CONFIRMATION TECHNIQUES FOR DIAZINON METABOLITES IN SAMPLE MATERIAL. THESE DERIVATIVES CHROMATOGRAPHED WELL. ELECTROLYTIC CONDUCTION DETECTION PROVED SATISFACTORY WHEN APPLIED TO THE ANALYSIS OF THE 2 METABOLITES IN DOG URINE IN RANGE OF 1 PPM.

Transformation products|Pesticides -> Insecticides -> Organophosphorus insecticides -> Organothiophosphate insecticides -> Heterocyclic organothiophosphate insecticides -> Transformation products|Environmental transformation -> Pesticide transformation products (metabolite, successor)

Pyrimidinol is a known environmental transformation product of Diazinon and Diazoxon.|G 27550 (2-isopropyl-4-methyl-6-hydroxypyrimidine) is a known environmental transformation product of Diazinon.