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Cinmetacin

Cinmetacin structure

CAS No:
20168-99-4
Formula:
C21H19NO4
Chemical Name:
Cinmetacin
Synonyms:
1H-Indole-3-acetic acid,5-methoxy-2-methyl-1-(1-oxo-3-phenyl-2-propen-1-yl)-;Indole-3-acetic acid,1-cinnamoyl-5-methoxy-2-methyl-;1H-Indole-3-acetic acid,5-methoxy-2-methyl-1-(1-oxo-3-phenyl-2-propenyl)-;5-Methoxy-2-methyl-1-(1-oxo-3-phenyl-2-propen-1-yl)-1H-indole-3-acetic acid;1-Cinnamoyl-2-methyl-5-methoxyindolyl-3-acetic acid;Cinmetacin;Indolacin;Cinmethacin;Cindomet;1-Cinnamoyl-5-methoxy-2-methylindole-3-acetic acid
Categories:
Active Pharmaceutical Ingredients > Antipyretic Analgesics

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Cinmetacin Basic Attributes

Molecular Weight：

349.386

Exact Mass：

349.38

EC Number：

243-555-6

HScode：

2933990090

Characteristics

PSA：

68.5

XLogP3：

3.93900

Density：

1.19g/cm3

Melting Point：

170 °C

Boiling Point：

488ºC at 760mmHg

Flash Point：

248.9ºC

Refractive Index：

1.593

Water Solubility：

<1mg/L(25 ºC)

Vapor Pressure：

2.45E-10mmHg at 25°C

Toxicity：

LD50 in mice, rats (mg/kg): 360, 590 i.p.; 750, 1020 orally (Komatsu)

Drug Information

MeSH Entry Terms：

cinmethacin

Computed Properties

Molecular Weight:349.4
XLogP3:4.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:349.13140809
Monoisotopic Mass:349.13140809
Topological Polar Surface Area:68.5
Heavy Atom Count:26
Complexity:540
Undefined Bond Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Drug Function and Efficacy

Extract from the above information

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

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Specifications	API
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Ingredients	The main ingredient of this product is cinnamon.
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Registered Holders

NORTHEAST Pharmaceutical Group Co., Ltd.

China
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