Estradiol
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Estradiol
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CAS No:
50-28-2
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Formula:
C18H24O2
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Chemical Name:
Estradiol
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Synonyms:
Estra-1,3,5(10)-triene-3,17-diol (17β)-;Estradiol;(17β)-Estra-1,3,5(10)-triene-3,17-diol;Altrad;Bardiol;Beta-estradiol;Dihydrofollicular hormone;Dihydrofolliculin;Dihydromenformon;Dihydrotheelin;Dihydroxyestrin;Diogyn;Diogynets;3,17-Epidihydroxyestratriene;Estraldine;Dimenformon;Estrovite;Femestral;Femogen;Gynergon;Gynoestryl;Lamdiol;Macrodiol;Nordicol;Oestergon;Oestradiol;Oestroglandol;Ovahormon;Ovasterol;Ovastevol;Ovocyclin;Primofol;Profoliol;Progynon;Progynon DH;Syndiol;Theelin,dihydro-;Estra-1,3,5(10)-triene-3,17β-diol;Ginosedol;Estra-1,3,5(10)-triene-3,17-diol,(17β)-;β-Estradiol;(+)-3,17β-Estradiol;Oestra-1,3,5(10)-triene-3,17β-diol;3,17β-Dihydroxyestra-1,3,5(10)-triene;3,17β-Estradiol;Perlatanol;Aquadiol;Follicyclin;Corpagen;17β-Oestradiol;Estradiol-17β;Estrace;Compudose;Estraderm;Compudose 365;E 2;Compudose 200;Estrogel;Estraderm TTS;Oestrogel;Menorest;Systen;Evorel;Climaderm;13β-Methyl-1,3,5(10)-gonatriene-3,17β-ol;Estraderm TTS 50;Epiestriol 50;Estroclim 50;Dermestril;Climara;Oesclim;17β-Estradiol;Encore;Aerodiol;Divigel;Sandrena 1;Vagifem;Gelestra;Estraderm TTS 100;Zumenon;Vivelle;NSC 9895;Profoliol B;Ovocylin;Estring Vaginal Ring;Estroclim;Estradot;Femanest;Estrogel HBF;Absorlent Matrix;FemSeven;Estrapatch;Estraderm MX;Alora;Estasorb;Estredox;Estreva;Bio-E Gel;Benzogynestry;Estropause;Menostar;Evamist;Zesteem;Compudose 400;Compudose 100;Vivelle-Dot;Sprediol;Elestrim;873662-39-6;1050677-52-5;1206475-11-7
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CAS No:
Description
Estradiol is a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females.
Characteristics
40.46000
3.60920
Solid
1.17g/cm3
173-179 °C
445.9ºC at 760mmHg
209.6ºC
1.599
Soluble in dimethyl sulfoxide, ethanol , water, phosphate buffer saline, dimethyl formamide, acetone, dioxane and alkali hydroxides. Slightly soluble in vegetable oils.
2-8ºC
6.38X10-9 mm Hg at 25 deg C (est)
LD50 subcutaneous in rat: > 300mg/kg
Specific optical rotation at 25 °C for D (sodium) line: +76 deg at 25 °C/D to +83 deg at 25 °C/D (dioxane)
Odorless
10.46±0.03
Safety Information
III
6.1
2811
3
R45
S53-S45
KG2975000
T
Stable. Incompatible with strong oxidizing agents.
P201-P263-P281-P308 + P313
H351-H360Fd-H362
Estradiol Use and Manufacturing
1. Potent mammalian estrogenic hormone produced by the ovary.
2. Estradiol is the major estrogen secreted by the premenopausal ovary.
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