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Chlorpromazine

Chlorpromazine structure

CAS No:
50-53-3
Formula:
C17H19ClN2S
Chemical Name:
Chlorpromazine
Synonyms:
10H-Phenothiazine-10-propanamine,2-chloro-N,N-dimethyl-;Phenothiazine,2-chloro-10-[3-(dimethylamino)propyl]-;2-Chloro-N,N-dimethyl-10H-phenothiazine-10-propanamine;Aminazine;Ampliactil;2-Chloro-10-[3-(dimethylamino)propyl]phenothiazine;Chlorpromazine;CPZ;Fenactil;Fenaktyl;Fraction AB;Largactilothiazine;Largactyl;Megaphen;Novomazina;Phenactyl;Promazil;Propaphenin;Thorazine;Wintermin;Aminazin;Chlorderazin;HL 5746;Promactil;Prozil;Sanopron;Amplictil;Proma;Chlor-Promanyl;Elmarin;Chlorpromados;Esmind;2-Chloropromazine;Chlordelazin;Thorazin;BC 135;RP 4560;SKF 2601A;Chlropromados;2601A;NSC 167745;NSC 226514;Sedatil;Noiafren;Relitil;Largaltil;[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine
Categories:
Active Pharmaceutical Ingredients > Nervous System Drugs

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Description

Oily liquid; amine odor.

Chlorpromazine Basic Attributes

Molecular Weight：

318.86416

Exact Mass：

318.86

EC Number：

200-045-8

HScode：

2934999090

Characteristics

PSA：

31.8

XLogP3：

4.9

Appearance：

Solid

Density：

1.2±0.1 g/cm3

Melting Point：

<25 °C

Boiling Point：

200-205 °C @ Press: 0.8 Torr

Flash Point：

226.0±28.7 °C

Refractive Index：

1.623

Water Solubility：

4.17e-03 g/L

Storage Conditions：

Store in tight, light-resistant container as defined in the USP-NF. This material should be handled and stored per label instructions to ensure product integrity.

Vapor Pressure：

5.17X10-6 mm Hg at 25 deg C (est)

Toxicity：

LD50 oral in rat: 142mg/kg

Odor：

Amine odor

PH：

Alkaline reaction

PKA：

9.3(at 25 °C)

Safety Information

Stability/Shelf Life：

Oral preparations of chlorpromazine hydrochloride should be stored in tightly closed containers Slight yellowish discoloration of the oral solutions or injection will not affect potency or efficacy, but they should not be used if markedly discolored or if a precipitate is present. At the time of manufacture, air in the containers of the commercially available chlorpromazine hydrochloride injection is replaced with nitrogen to avoid oxidation.

Precautionary statement(s)：

P201, P260, P261, P263, P264, P270, P271, P272, P273, P280, P301+P310, P302+P352, P304+P340, P308+P313, P311, P321, P330, P333+P313, P363, P391, P403+P233, P405, P501

Hazard Statements：

H301

Chlorpromazine Use and Manufacturing

antiemetic, antipsychotic

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Specifications	2ml: Chlorpromazine hydrochloride 25mg, Promethazine hydrochloride 25mg
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Recommended Suppliers of Chlorpromazine

Shaanxi Dideu Medichem Co. Ltd Contact Supplier

CN
5 YRS

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Chlorpromazine 99% solid Dideu

CAS No.: 50-53-3

Grade: Pharmaceutical Grade

Content: 99%

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