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Lypressin

Lypressin structure

CAS No:
50-57-7
Formula:
C46H65N13O12S2
Chemical Name:
Lypressin
Synonyms:
LVP;diapid;postacton;LYPRESSIN;LYSPRESSIN;Lysipressin;Vasopressin;syntopressin;CYFQNCPKG-NH2;lysinepitressin
Categories:
Biochemical Engineering > Amino Acids and Derivatives

Description

Lysipressin is Antidiuretic hormone that have been found in pigs and some marsupial families. Induces contraction of the rabbit urinary bladder smooth muscle, activate adenylate-cyclase. Sequence: Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2(Disulfide bridge: Cys1-Cys6).

Lypressin is a cyclic peptide.|The porcine antidiuretic hormone (VASOPRESSINS). It is a cyclic nonapeptide that differs from ARG-VASOPRESSIN by one amino acid, containing a LYSINE at residue 8 instead of an ARGININE. Lys-vasopressin is used to treat DIABETES INSIPIDUS or to improve vasomotor tone and BLOOD PRESSURE.

Lypressin Basic Attributes

Molecular Weight：

1056.22

Exact Mass：

1055.431763

EC Number：

200-050-5

DSSTox ID：

DTXSID8048575

HScode：

2937190000

Characteristics

PSA：

476.15000

XLogP3：

-5.74

Density：

1.3±0.1 g/cm3

Boiling Point：

1610.4±65.0 °C at 760 mmHg

Flash Point：

927.7±34.3 °C

Refractive Index：

1.581

Storage Conditions：

−20°C

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

hazard class code：

safety instructions：

RTECS Number：

YW8659000

Marks：

Precautionary statement(s)：

P261

Hazard Statements：

H332

GHS Classification：

|Warning|H332 (100%): Harmful if inhaled [Warning Acute toxicity, inhalation]|P261, P271, P304+P312, P304+P340, and P312|Aggregated GHS information provided by 39 companies from 1 notifications to the ECHA C&L Inventory.

Drug Information

MeSH：

Agents acting to arrest the flow of blood. Absorbable hemostatics arrest bleeding either by the formation of an artificial clot or by providing a mechanical matrix that facilitates clotting when applied directly to the bleeding surface. These agents function more at the capillary level and are not effective at stemming arterial or venous bleeding under any significant intravascular pressure. (See all compounds classified as Hemostatics.)|Agents that reduce the excretion of URINE, most notably the octapeptide VASOPRESSINS. (See all compounds classified as Antidiuretic Agents.)|Drugs used to cause constriction of the blood vessels. (See all compounds classified as Vasoconstrictor Agents.)

MeSH Entry Terms：

8 Lysine Vasopressin

Lypressin Use and Manufacturing

Hormone (antidiuretic).

Computed Properties

Molecular Weight:1056.2
XLogP3:-3.9
Hydrogen Bond Donor Count:13
Hydrogen Bond Acceptor Count:16
Rotatable Bond Count:19
Exact Mass:1055.43170691
Monoisotopic Mass:1055.43170691
Topological Polar Surface Area:476
Heavy Atom Count:73
Complexity:1960
Undefined Atom Stereocenter Count:8
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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Guide of Lypressin

Description
Basic Attributes
Characteristics
Safety Information
Drug Information
Use and Manufacturing
Computed Properties
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