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Hexoprenaline

Hexoprenaline structure

CAS No:
3215-70-1
Formula:
C22H32N2O6
Chemical Name:
Hexoprenaline
Synonyms:
1,2-Benzenediol,4,4′-[1,6-hexanediylbis[imino(1-hydroxy-2,1-ethanediyl)]]bis-;Benzyl alcohol,α,α′-[hexamethylenebis(iminomethylene)]bis[3,4-dihydroxy-;4,4′-[1,6-Hexanediylbis[imino(1-hydroxy-2,1-ethanediyl)]]bis[1,2-benzenediol];Hexoprenaline;Ipradol;N,N′-Bis[2-(3,4-dihydroxyphenyl)-2-hydroxyethyl]hexamethylenediamine;Broncholysin;Byk 1512;ST 1512
Categories:
Organic Chemistry > Amides

Description

Hexoprenaline is a stimulant of beta 2 adrenergic receptors. It is used as a bronchodilator, antiasthmatic, and tocolytic agent.|Stimulant of adrenergic beta 2 receptors. It is used as a bronchodilator, antiasthmatic agent, and tocolytic agent.

Hexoprenaline Basic Attributes

Molecular Weight：

518.58

Exact Mass：

420.50

UNII：

G9L6B3W684

DSSTox ID：

DTXSID7048322

ATC Code：

R - Respiratory system

Characteristics

PSA：

145.44000

XLogP3：

2.79740

Density：

1.302g/cm3

Melting Point：

162-165° (hemihydrate)

Boiling Point：

707.8ºC at 760mmHg

Flash Point：

186ºC

Drug Information

MeSH：

Agents that cause an increase in the expansion of a bronchus or bronchial tubes. (See all compounds classified as Bronchodilator Agents.)|Compounds bind to and activate ADRENERGIC BETA-2 RECEPTORS. (See all compounds classified as Adrenergic beta-2 Receptor Agonists.)|Drugs that prevent preterm labor and immature birth by suppressing uterine contractions (TOCOLYSIS). Agents used to delay premature uterine activity include magnesium sulfate, beta-mimetics, oxytocin antagonists, calcium channel inhibitors, and adrenergic beta-receptor agonists. The use of intravenous alcohol as a tocolytic is now obsolete. (See all compounds classified as Tocolytic Agents.)

MeSH Entry Terms：

Ginipral

Hexoprenaline Use and Manufacturing

Hexoprenaline acts as a β2-adrenoreceptor agonist/betamimetic and a vasoactive agent.

Computed Properties

Molecular Weight:420.5
XLogP3:1.1
Hydrogen Bond Donor Count:8
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:13
Exact Mass:420.22603674
Monoisotopic Mass:420.22603674
Topological Polar Surface Area:145
Heavy Atom Count:30
Complexity:417
Undefined Atom Stereocenter Count:2
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes