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Aspon

Aspon structure

CAS No:
3244-90-4
Formula:
C12H28O5P2S2
Chemical Name:
Aspon
Synonyms:
Thiodiphosphoric acid ([(HO)2P(S)]2O),OP,OP,OP′,OP′-tetrapropyl ester;Thiopyrophosphoric acid ([(HO)2PS]2O),tetrapropyl ester;Propyl thiopyrophosphate ([(PrO)2P(S)]2O);Thiodiphosphoric acid ([(HO)2P(S)]2O),tetrapropyl ester;A 42;ASP 51;E 8573;Aspon;NPD;Tetra-n-propyl dithionopyrophosphate;Tetra-n-propyl dithiopyrophosphate;O,O,O,O-Tetrapropyl dithiopyrophosphate;NSC 2550
Categories:
Agrochemicals > Insecticides

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Description

ASPON (TM) is amber liquid. Miscible with most organic solvents; insoluble in water.

Aspon Basic Attributes

Molecular Weight：

378.43

Exact Mass：

378.43

EC Number：

221-817-0

UNII：

PC55IL137P

NSC Number：

2550

DSSTox ID：

DTXSID6032510

Color/Form：

Technical product (93-96% pure) is a straw to amber-colored liquid.

Characteristics

PSA：

129.95000

XLogP3：

6.45960

Density：

1.173g/cm3

Melting Point：

-44.9°C

Boiling Point：

381.6ºC at 760mmHg

Flash Point：

149 °C

Refractive Index：

1.498

Water Solubility：

Miscible with acetone, ethanol, kerosene, 4-methylpentan-2-one, xylene (Technical product, 93-96% pure)

Vapor Pressure：

The vapor pressure at 25 deg C is 13 mPa (Technical product, 93- 96% pure)

Toxicity：

Oral-Rat LD50: 450 mg/kg

Flammability characteristics：

Combustion produces toxic phosphorus oxide and sulfur oxide gas

Odor：

Technical product (93-96% pure) has a faint aromatic odor.

Experimental Properties：

In water buffered at pH 7, 50% loss occurs in 32 days at 40 °C. Thermally stable < 100 °C.

Corrosivity：

Corrosive to steel (Technical product, 93-96% pure)

Safety Information

Packing level：

III

Hazard category：

6.1(b)

Transport codes：

3018

hazard class code：

21/22-50/53

safety instructions：

36/37-60-61

RTECS Number：

XN4550000

Marks：

Xn,N

Storage features：

The warehouse is ventilated, low temperature and dry; stored and transported separately from food materials

Stability/Shelf Life：

STABLE WITH INSIGNIFICANT HYDROLYSIS IN WATER AT ROOM TEMP; STABLE FOR AT LEAST 24 HR @ 100 DEG C, BUT DECOMP, WITHOUT EXPLOSIVE HAZARD @ 149 DEG C; DISCOLORATION & PHYSICAL CHANGES MAY OCCUR ON PROLONGED CONTACT WITH METAL /TECHNICAL/

Precautionary statement(s)：

P264, P270, P273, P280, P301+P312, P302+P352, P312, P322, P330, P363, P391, P501

Hazard Statements：

H302

Disposal Methods：

SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.

GHS Classification：

|Warning|H302: Harmful if swallowed [Warning Acute toxicity, oral]|P264, P270, P273, P280, P301+P312, P302+P352, P312, P322, P330, P363, P391, and P501|H302+H312 (92.68%): Harmful if swallowed or in contact with skin [Warning Acute toxicity, oral; acute toxicity, dermal]|Aggregated GHS information provided by 41 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Toxicity

Toxicity class：

highly toxic

Drug Information

Reported Fatal Dose：

3. 3= MODERATELY TOXIC; PROBABLE ORAL LETHAL DOSE (HUMAN) 0.5-5 G/KG; BETWEEN 1 OZ & 1 PINT (OR 1 LB) FOR 70 KG PERSON (150 LB).

Mechanism of Action：

PARATHION & ITS RELATIVES ARE KNOWN TO INHIBIT ENZYME CHOLINESTERASE IN ALL PARTS OF THE BODY BY PHOSPHORYLATING THE ACTIVE SITE. /PARATHION/

Human Toxicity Excerpts：

SYMPTOMATOLOGY: 1. NAUSEA...VOMITING, ABDOMINAL CRAMPS, DIARRHEA, EXCESSIVE SALIVATION... 2. HEADACHE, GIDDINESS, VERTIGO & WEAKNESS. 3. RHINORRHEA & SENSATION OF TIGHTNESS IN CHEST ARE COMMON IN INHALATION EXPOSURE. 4. BLURRING OR DIMNESS OF VISION, MIOSIS... TEARING, CILIARY MUSCLE SPASM, LOSS OF ACCOMMODATION & OCULAR PAIN... MYDRIASIS...SOMETIMES SEEN...PROBABLY DUE TO SYMPATHO-ADRENAL DISCHARGE. 5. LOSS OF MUSCLE COORDINATION, SLURRING OF SPEECH, FASCICULATIONS & TWITCHING OF MUSCLES (PARTICULARLY OF TONGUE & EYELIDS), & GENERALIZED PROFOUND WEAKNESS. 6. MENTAL CONFUSION, DISORIENTATION & DROWSINESS. /PARATHION/|SYMPTOMATOLOGY: 7. DIFFICULTY IN BREATHING, EXCESSIVE SECRETION OF SALIVA & OF RESP TRACT MUCUS, ORONASAL FROTHING, CYANOSIS, PULMONARY RALES & RHONCHI & HYPERTENSION, (PRESUMABLY DUE TO ASPHYXIA). 8. RANDOM JERKY MOVEMENTS, INCONTINENCE, CONVULSIONS, & COMA. 9. DEATH PRIMARILY DUE TO RESP ARREST ARISING FROM FAILURE OF RESP CENTER, PARALYSIS OF RESP MUSCLES, INTENSE BRONCHOCONSTRICTION OR ALL THREE. /PARATHION/

Aspon Use and Manufacturing

Methods of Manufacturing

REACTION OF O,O-DI-N-PROPYL PHOSPHOROCHLORIDOTHIOATE WITH WATER, IN THE PRESENCE OF PYRIDINE

Uses

Insecticide, acaricide. ASPON (TM) is an organophosphorus, nonsystemic insecticide used to control chinch bugs in lawns

Production

(1971) LESS THAN 4.54X10+8 G (EST)|(1974) 2.27X10+8 G (CONSUMPTION)

Consumption Patterns：

ESSENTIALLY 100% AS AN INSECTICIDE FOR SOD WEBWORMS & CINCHBUGS ON LAWN & TURF

Formulations：

'ASPON', EMULSIFIABLE CONCENTRATE (480 G ACTIVE INGREDIENT/L); GRANULES (50 G/KG).|WETTABLE POWDER (25%); EMULSIFIABLE CONCENTRATE (85%), (6 LB/GAL)...|Technical product is 93-96% pure.|'Aspon E', EC(240 or 720 g a.i./l); 'Aspon 5GA', 'Aspon 25G', Aspon 25G', GR(50 or 250 g/kg)

Manufacturing Info：

/IT IS/...PROTECTED BY US PATENT 2663722.|COMPATIBLE WITH COMMONLY-USED PEST CONTROL MATERIALS. CONSIDERABLE CONTACT & FUMIGANT INSECTICIDAL PROPERTY, ESPECIALLY AGAINST APHIDS--SOME RESIDUAL ACTIVITY. ACTIVE AGAINST CINCH BUGS, BLISSUS SPECIES, IN EASTERN USA. RECOMMENDED FOR USE ON TURF. NO PHYTOXICITY REPORTED AT INSECTICIDAL CONCENTRATIONS.|Aspon's registration has been cancelled

Computed Properties

Molecular Weight:378.4
XLogP3:6
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:14
Exact Mass:378.08534033
Monoisotopic Mass:378.08534033
Topological Polar Surface Area:110
Heavy Atom Count:21
Complexity:299
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes