Nickel carbonate (NiCO3)

118.70200

117.92000

240-408-8

WM50SQU829

0927

3288|3082

DTXSID3025708

C45870

Green rhombohedral crystals

2836999000

63.19000

-2.44700

DryPowder; Liquid; OtherSolid; WetSolid

4 x 10^-6 g/cm³

270 °C (decomp)

333.6ºC at 760 mmHg

169.8ºC

Solubility in water, mg/l at 25°C: 93 (practically insoluble )

Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

III

6

UN 3077

R22; R40; R43

S22-S24/25

QR6200000

Xn

Store only in original packaging. Separated from food and feedstuffs and acids. Store in an area without drain or sewer access. Provision to contain effluent from fire extinguishing.

Stable. Incompatible with strong acids.

P201, P202, P261, P264, P270, P272, P273, P280, P281, P301+P312, P302+P352, P308+P313, P321, P330, P333+P313, P363, P391, P405, P501

H302

SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.

Not combustible. Gives off irritating or toxic fumes (or gases) in a fire.

|Danger|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P201, P202, P260, P261, P264, P270, P271, P272, P273, P280, P281, P285, P301+P312, P302+P352, P304+P312, P304+P340, P304+P341, P308+P313, P312, P314, P321, P330, P332+P313, P333+P313, P342+P311, P362, P363, P391, P405, and P501|Aggregated GHS information provided by 8 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.|H302+H332 (13.27%): Harmful if swallowed or if inhaled [Warning Acute toxicity, oral; acute toxicity, inhalation]|Aggregated GHS information provided by 113 companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.|Warning|P201, P202, P261, P264, P270, P272, P273, P280, P281, P301+P312, P302+P352, P308+P313, P321, P330, P333+P313, P363, P391, P405, and P501|The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.|Aggregated GHS information provided by 64 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.|H302: Harmful if swallowed [Warning Acute toxicity, oral]|P201, P202, P260, P261, P264, P270, P271, P272, P273, P280, P281, P284, P301+P312, P302+P352, P304+P340, P305+P351+P338, P308+P313, P310, P314, P320, P321, P330, P333+P313, P337+P313, P363, P391, P403+P233, P405, and P501

In case of fire in the surroundings, use appropriate extinguishing media.

SRP: Contaminated protective clothing should be segregated in such a manner so that there is no direct personal contact by personnel who handle, dispose, or clean the clothing. Quality assurance to ascertain the completeness of the cleaning procedures should be implemented before the decontaminated protective clothing is returned for reuse by the workers.|SRP: The scientific literature for the use of contact lenses in industry is conflicting. The benefit or detrimental effects of wearing contact lenses depend not only upon the substance, but also on factors including the form of the substance, characteristics and duration of the exposure, the uses of other eye protection equipment, and the hygiene of the lenses. However, there may be individual substances whose irritating or corrosive properties are such that the wearing of contact lenses would be harmful to the eye. In those specific cases, contact lenses should not be worn. In any event, the usual eye protection equipment should be worn even when contact lenses are in place.

Vacated 1989 OSHA PEL TWA 0.1 mg/cu m is still enforced in some states. /Nickel soluble compounds, as Ni/|Permissible Exposure Limit: Table Z-1 8-hr Time Weighted Avg: 1 mg/cu m. /Nickel, metal and insoluble cmpd, as Ni/

NIOSH considers nickel metal and other compounds (as Ni) to be a potential occupational carcinogen. /Nickel metal and other compounds (as Ni)/|NIOSH usually recommends that occupational exposures to carcinogens be limited to the lowest feasible concentration. /Nickel metal and other compounds (as Ni)/|Recommended Exposure Limit: 10 Hr TWA 0.015 mg/cu m. /Nickel metal and other compounds (as Ni)/

Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.

Store only in original packaging. Separated from food and feedstuffs and acids. Store in an area without drain or sewer access. Provision to contain effluent from fire extinguishing.

Evaporation at 20 °C is negligible; a harmful concentration of airborne particles can, however, be reached quickly when dispersed.

The substance is irritating to the skin.

Repeated or prolonged contact may cause skin sensitization. Repeated or prolonged inhalation may cause asthma. The substance may have effects on the lungs. This substance is carcinogenic to humans if inhaled.

AVOID ALL CONTACT!

Use closed system or ventilation (not if powder).

Protective gloves. Protective clothing.

Wear safety goggles or eye protection in combination with breathing protection.

Listed as a hazardous air pollutant (HAP) generally known or suspected to cause serious health problems. The Clean Air Act, as amended in 1990, directs EPA to set standards requiring major sources to sharply reduce routine emissions of toxic pollutants. EPA is required to establish and phase in specific performance based standards for all air emission sources that emit one or more of the listed pollutants. Nickel carbonate is included on this list.

... Nickel carbonate is insoluble in water. ... Respiratory absorption with secondary gastrointestinal absorption of nickel (insoluble compounds) is the major route of entry during occupational exposure. A significant quantity of inhaled material is swallowed following mucocillary clearance from the respiratory tract. Poor personal hygiene & work practices can contribute to gastrointestinal exposure. Percutaneous absorption is negligible, quanitatively, but is important in the pathogenesis of contact hypersensitivity. Absorption is related to the solubility of the compound /& nickel carbonate is classified as an insoluble salt/. Nickel carbonate ... induced local mesenchymal tumors in a variety of experimental animals after im, sc, ip, intrapleural, intraocular, intraosseous, intrarenal, intra-articular, intratesticular or intra-adipose administration.

Aquatic Fate: Under aerobic conditions and pH below 9 ... nickel forms with ... carbonate ... /and is/ sufficiently soluble to maintain aqueous an Ni(2+) concn above 10-6 M (60 ug/l). Above pH 9, precipitation of the ... carbonate exhibits some control on nickel mobility.

NICKEL CARBONATE WAS GIVEN INTRATRACHEALLY TO MICE (0.05 MG) & URINARY EXCRETION & LUNG CLEARANCE OF NICKEL DETERMINED 1-6 DAYS FOLLOWING ADMIN. MORE NICKEL EXCRETED IN URINE DURING 1ST DAY THAN REMAINDER OF WK. CLEARANCE OF NICKEL CARBONATE FROM LUNG WAS MODERATE.

Carcinogens

Fresh air, rest. Refer for medical attention.

Wear protective gloves when administering first aid. Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention .

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

Basic treatment: Establish a patent airway. Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilation if necessary. Administer oxygen by nonrebreather mask at 10 t0 15 L/min. Monitor for shock and treat if necessary ... . Monitor for pulmonary edema and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with normal saline during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 ml/kg up to 200 ml of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool ... . /Nickel and related compounds/|Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious. Positive pressure ventilation techniques with a bag valve mask device may be beneficial. Monitor cardiac rhythm and treat arrhythmias if necessary ... . Consider drug therapy for pulmonary edema ... . Start an IV with D5W /SRP: "To keep open", minimal flow rate/. Use lactated Ringer's if signs of hypovolemia are present. For hypotension with signs of hypovolemia, administer fluid cautiously. Consider vasopressors for hypotension with a normal fluid volume. Watch for signs of fluid overload ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Nickel and related compounds/

Human peripheral lymphocytes were incubated 4 hr with 50 uM nickel carbonate. Nickel carbonate formed paracrystalline particles apparently with albumin, histidine, and lysine of the culture medium; the particles were accumulated along the cell membranes of the lymphocytes (both outside and inside of the cells) especially in lymphocytes from subjects with nickel allergy. Lymphocytes from normal subjects formed more phagocytic pseudopodia than lymphocytes from the sensitized subjects.

nickel carbonate

The substance can be absorbed into the body by inhalation of its aerosol and by ingestion.

Cough.

Redness. Pain.

Redness.

9.08X10+8 GRAMS ARE USED IN NICKEL CATALYST PRODUCTION FOR ORGANIC CHEM MANUFACTURE, PETROLEUM REFINING AND EDIBLE OIL HARDENING EACH YEAR (1972).

Reagent grades; -325 mesh, 99.5% purity grade; powder grade; basic & high-purity LH grade

All other basic inorganic chemical manufacturing|Carbonic acid, nickel(2+) salt (1:1): ACTIVE

Health Hazards -> Carcinogens