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Emepronium bromide

Emepronium bromide structure

CAS No:
3614-30-0
Formula:
C20H28N.Br
Chemical Name:
Emepronium bromide
Synonyms:
Benzenepropanaminium,N-ethyl-N,N,α-trimethyl-γ-phenyl-,bromide (1:1);Ammonium,ethyldimethyl(1-methyl-3,3-diphenylpropyl)-,bromide;Ethyldimethyl(1-methyl-3,3-diphenylpropyl)ammonium bromide;Benzenepropanaminium,N-ethyl-N,N,α-trimethyl-γ-phenyl-,bromide;Cetiprin;Dimethylethyl(β-benzhydrylisopropyl)-ammonium bromide;Emepronium bromide;Ethyl(3,3-diphenyl-1-methylpropyl)dimethylammonium bromide;Emepron bromide;Restenacht;Hexanium;(1-Methyl-3,3-diphenylpropyl)dimethylethylammonium bromide;Emeprone bromide;Emeprone;Uro-Ripirin;Ripirin
Categories:
Organic Chemistry > Amides

Description

A muscarinic antagonist used mainly in the treatment of urinary syndromes. It is incompletely absorbed from the gastrointestinal tract and does not cross the blood-brain barrier.

Emepronium bromide Basic Attributes

Molecular Weight：

362.34702

Exact Mass：

361.14100

EC Number：

222-786-6

Characteristics

PSA：

XLogP3：

1.69740

Melting Point：

204 °C

Drug Information

MeSH：

Drugs that bind to but do not activate MUSCARINIC RECEPTORS, thereby blocking the actions of endogenous ACETYLCHOLINE or exogenous agonists. Muscarinic antagonists have widespread effects including actions on the iris and ciliary muscle of the eye, the heart and blood vessels, secretions of the respiratory tract, GI system, and salivary glands, GI motility, urinary bladder tone, and the central nervous system. (See all compounds classified as Muscarinic Antagonists.)|Agents that inhibit the actions of the parasympathetic nervous system. The major group of drugs used therapeutically for this purpose is the MUSCARINIC ANTAGONISTS. (See all compounds classified as Parasympatholytics.)|Drugs used in the treatment of urogenital conditions and diseases such as URINARY INCONTINENCE; PROSTATIC HYPERPLASIA; and ERECTILE DYSFUNCTION. (See all compounds classified as Urological Agents.)

MeSH Entry Terms：

Bromide, Emepronium

Emepronium bromide Use and Manufacturing

Antispasmodic. Used in treatment of urinary incontinence. Anticholinergic overactive bladder.

Computed Properties

Molecular Weight:362.3
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:6
Exact Mass:361.14051
Monoisotopic Mass:361.14051
Heavy Atom Count:22
Complexity:266
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes