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Dimebon

Dimebon structure

CAS No:
3613-73-8
Formula:
C21H25N3
Chemical Name:
Dimebon
Synonyms:
1H-Pyrido[4,3-b]indole,2,3,4,5-tetrahydro-2,8-dimethyl-5-[2-(6-methyl-3-pyridinyl)ethyl]-;1H-Pyrido[4,3-b]indole,2,3,4,5-tetrahydro-2,8-dimethyl-5-[2-(6-methyl-3-pyridyl)ethyl]-;2,3,4,5-Tetrahydro-2,8-dimethyl-5-[2-(6-methyl-3-pyridinyl)ethyl]-1H-pyrido[4,3-b]indole;Dimeboline;Preparation 84;Dimebolin;Dimebone;Dimebon;2,3,4,5-Tetrahydro-2,8-dimethyl-5-[2-(6-methylpyridin-3-yl)ethyl]-1H-pyrido[4,3-b]indole;Latrepirdine;2,8-Dimethyl-5-[2-(6-methylpyridin-3-yl)ethyl]-3,4-dihydro-1H-pyrido[4,3-b]indole;2,8-Dimethyl-5-[2-(6-methyl-pyridin-3-yl)-ethyl]-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole;12687-54-6;20684-30-4
Categories:
Pharmaceutical Intermediates > Heterocyclic Compound

Description

2,8-dimethyl-5-[2-(6-methyl-3-pyridinyl)ethyl]-3,4-dihydro-1H-pyrido[4,3-b]indole is a member of indoles.|Latrepirdine has been investigated for the treatment of Alzheimer's Disease and Huntington's Disease.

Dimebon Basic Attributes

Molecular Weight：

319.44

Exact Mass：

319.44

EC Number：

1312995-182-4

UNII：

OD9237K1Z6

DSSTox ID：

DTXSID20189705

Characteristics

PSA：

21.1

XLogP3：

3.96

Appearance：

White powder

Density：

1.1±0.1 g/cm3

Melting Point：

115-116 °C

Boiling Point：

505.7±50.0 °C at 760 mmHg

Flash Point：

259.7±30.1 °C

Refractive Index：

1.629

Safety Information

Precautionary statement(s)：

P264, P273, P280, P305+P351+P338, P337+P313, P501

Hazard Statements：

H319

GHS Classification：

|Warning|H319 (56.72%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]|P264, P273, P280, P305+P351+P338, P337+P313, and P501|Aggregated GHS information provided by 67 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Drug Information

MeSH Entry Terms：

dimebolin

Dimebon Use and Manufacturing

Non-steroidal anti-inflammatory with analgesic and antipyretic effects

Computed Properties

Molecular Weight:319.4
XLogP3:3.5
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:319.204847810
Monoisotopic Mass:319.204847810
Topological Polar Surface Area:21.1
Heavy Atom Count:24
Complexity:425
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes