(±)-Mercaptosuccinic acid
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(±)-Mercaptosuccinic acid
structure -
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CAS No:
70-49-5
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Formula:
C4H6O4S
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Chemical Name:
(±)-Mercaptosuccinic acid
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Synonyms:
Butanedioic acid,2-mercapto-;Succinic acid,mercapto-;Butanedioic acid,mercapto-;2-Mercaptobutanedioic acid;Mercaptosuccinic acid;Thiomalic acid;2-Thiomalic acid;α-Mercaptosuccinic acid;2-Mercaptosuccinic acid;Monomercaptosuccinic acid;DL-Mercaptosuccinic acid;DL-Thiomalic acid;(±)-Mercaptosuccinic acid;Mercaptobutanedioic acid;NSC 7302;2-Sulfanylbutanedioic acid;644-87-1
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CAS No:
Description
white to almost white crystalline powder
Thiomalic acid is a C4-dicarboxylic acid. It derives from a succinic acid. It is a conjugate acid of a thiomalate(1-).
(±)-Mercaptosuccinic acid Basic Attributes
150.15
150.15
1099858
200-736-4
7302
DTXSID20861615
29309070
Characteristics
75.6
-0.4
White to almost white Crystalline Powder
1.5±0.1 g/cm3
149 °C
241.69°C (rough estimate)
108.8±24.6 °C
1.556
H2O: 150 g/L (20 ºC)
2-8°C
Safety Information
III
8
1759
3
22-36/37/38-34-20/21/22
26-36-36/37/39-45-27
WM8225000
Xn,C
P261-P305 + P351 + P338
H302-H315-H319-H335
|Warning|H302 (97.52%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P271, P272, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P333+P313, P337+P313, P362, P363, P403+P233, P405, and P501|Aggregated GHS information provided by 127 companies from 9 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
(±)-Mercaptosuccinic acid Use and Manufacturing
Maleic anhydride is hydrated to generate maleic acid, which is then reacted with hydrogen sulfide to obtain the product. For laboratory preparation, 23.2g malic acid and 20g thioacetic acid can be dissolved in 80ml ethyl acetate and refluxed for 1h. After cooling, 400ml of benzene is added for extraction, activated carbon is added for decolorization, the carbon is removed by filtration, and benzene is recovered to obtain a crude product. After refining, 32g of acetylthiomalic acid was obtained, with a melting point of 126°C. After further hydrolysis, mercaptosuccinic acid is obtained.
This product is the main component of cold foiling agent, also used in complex concealment, biochemical research, heavy metal antidote and rubber industry.
Butanedioic acid, 2-mercapto-: ACTIVE
Computed Properties
Molecular Weight:150.16
XLogP3:-0.4
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:149.99867984
Monoisotopic Mass:149.99867984
Topological Polar Surface Area:75.6
Heavy Atom Count:9
Complexity:133
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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