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Home > Encyclopedia > 2-[2-[4-(Diphenylmethyl)-1-piperazinyl]ethoxy]ethanol

2-[2-[4-(Diphenylmethyl)-1-piperazinyl]ethoxy]ethanol

pharmaceutical raw materials
2-[2-[4-(Diphenylmethyl)-1-piperazinyl]ethoxy]ethanol structure

2-[2-[4-(Diphenylmethyl)-1-piperazinyl]ethoxy]ethanol 

structure
  • CAS No:

    3733-63-9

  • Formula:

    C21H28N2O2

  • Chemical Name:

    2-[2-[4-(Diphenylmethyl)-1-piperazinyl]ethoxy]ethanol

  • Synonyms:

    Ethanol,2-[2-[4-(diphenylmethyl)-1-piperazinyl]ethoxy]-;2-[2-[4-(Diphenylmethyl)-1-piperazinyl]ethoxy]ethanol;UCB 1402;Decloxizine;NSC 289116;2-[2-(4-Benzhydrylpiperazin-1-yl)ethoxy]ethanol

  • Categories:

    Active Pharmaceutical Ingredients  >  Antiallergic Drugs

Description

Decloxizine(UCB-1402; NSC289116) is a histamine 1 receptor antagonist.

2-[2-[4-(Diphenylmethyl)-1-piperazinyl]ethoxy]ethanol Basic Attributes

340.45922

340.46

919C49XAYD

289116

DTXSID40190777

2933599090

Characteristics

35.9

1.43

white or similar to white powder

1.1±0.1 g/cm3

185 °C @ Press: 5 x 10-3 Torr

239.5±27.3 °C

1.576

Oral-rat LD50: 840 mg/kg; Oral-Mouse LD50: 470 mg/kg

Flammable; burning produces toxic nitrogen oxide fumes

Safety Information

Ventilated, low temperature and dry; stored separately from food materials in warehouse

Toxicity

highly toxic

Drug Information

decloxazine

Computed Properties

Molecular Weight:340.5
XLogP3:3.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:8
Exact Mass:340.215078140
Monoisotopic Mass:340.215078140
Topological Polar Surface Area:35.9
Heavy Atom Count:25
Complexity:328
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Drug Function and Efficacy

Vitamins and minerals are both important substances that are essential for maintaining normal metabolism and health. They are important components of various coenzymes and hormones. Their deficiency can lead to metabolic disorders and cause various diseases.

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

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