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Neamine

Neamine structure

CAS No:
3947-65-7
Formula:
C12H26N4O6
Chemical Name:
Neamine
Synonyms:
D-Streptamine,2-deoxy-4-O-(2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl)-;Neomycin A;2-Deoxy-4-O-(2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl)-D-streptamine;Neamine;Neamin;Negamicin;Nebramycin X;Dekamycin V;O-2,6-Diamino-2,6-dideoxy-α-D-glucopyranosyl-(1→4)-1,3-diamino-1,2,3-trideoxy-D-myo-inositol;ST 7;(+)-Neamine;1392-64-9;1400-49-3;157719-56-7;1195510-56-5
Categories:
Analytical Chemistry > Standard

Description

ChEBI: 2-Deoxy-D-streptamine glycosylated at the 4-oxygen with a 6-amino-alpha-D-glucosaminyl group.

Neamine is 2-Deoxy-D-streptamine glycosylated at the 4-oxygen with a 6-amino-alpha-D-glucosaminyl group. It has a role as an antibacterial agent. It is a 2,6-dideoxy-alpha-D-glucoside and an aminoglycoside. It is a conjugate base of a neamine(4+).|Neamine is the minor component of the neomycin complex, a broad spectrum aminoglycoside antibiotic derived from Streptomyces fradiae with antibacterial activity.

Neamine Basic Attributes

Molecular Weight：

322.36

Exact Mass：

322.36

UNII：

5981U00LY0

DSSTox ID：

DTXSID7023358

NCI Thesaurus Code：

C76155

Characteristics

PSA：

203.46000

XLogP3：

-2.78

Density：

1.5±0.1 g/cm3

Melting Point：

256 °C (decomp)

Boiling Point：

577.9±50.0 °C at 760 mmHg

Flash Point：

303.3±30.1 °C

Refractive Index：

1.649

Specific rotation：

D25+112.8° (c = 1)

Drug Information

MeSH Entry Terms：

neamin

Computed Properties

Molecular Weight:322.36
XLogP3:-5.4
Hydrogen Bond Donor Count:8
Hydrogen Bond Acceptor Count:10
Rotatable Bond Count:3
Exact Mass:322.18523456
Monoisotopic Mass:322.18523456
Topological Polar Surface Area:204
Heavy Atom Count:22
Complexity:378
Defined Atom Stereocenter Count:10
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes