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Cycloartenol

Cycloartenol structure

CAS No:
469-38-5
Formula:
C30H50O
Chemical Name:
Cycloartenol
Synonyms:
9,19-Cyclolanost-24-en-3-ol,(3β)-;Cycloartenol;9,19-Cyclo-9β-lanost-24-en-3β-ol;1H,19H-Cyclopropa[9,10]cyclopenta[a]phenanthrene,9,19-cyclolanost-24-en-3-ol deriv.;(3β)-9,19-Cyclolanost-24-en-3-ol;Handianol;9,19-Cyclo-24-lanosten-3β-ol;Cycloart-24-en-3β-ol;NSC 670193;1253203-48-3
Categories:
Pharmaceutical Intermediates > Bulk Drug Intermediates

Description

Cycloartenol, a phytosterol compound, is one of the key precusor substances for biosynthesis of numerous sterol compounds. Cycloartenol inhibits the migration of glioma cells and suppresses the phosphorylation of the p38 MAP kinase. Cycloartenol has a variety of pharmacological activities such as anti-inflammatory, anti-tumor, antioxidant, antibiosis and anti-alzheimer's disease. Cycloartenol also plays an important role in the process of plant growth and development[1][2].

Solid

Cycloartenol is a pentacyclic triterpenoid, a 3beta-sterol and a member of phytosterols. It has a role as a plant metabolite. It derives from a hydride of a lanostane.

Cycloartenol Basic Attributes

Molecular Weight：

426.71700

Exact Mass：

426.72

UNII：

YU32VE82N3

Characteristics

PSA：

20.23000

XLogP3：

8.16890

Appearance：

Solid

Density：

1.01 g/cm3

Melting Point：

103.0-103.5 °C

Boiling Point：

505.5ºC at 760 mmHg

Flash Point：

221.9ºC

Refractive Index：

1.538

Water Solubility：

2.31e-005 mg/L @ 25 °C (est)

Safety Information

wgk germany：

safety instructions：

22-24/25

Marks：

Xi: Irritant;

Drug Information

MeSH Entry Terms：

cycloartenol

Computed Properties

Molecular Weight:426.7
XLogP3:9.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:4
Exact Mass:426.386166214
Monoisotopic Mass:426.386166214
Topological Polar Surface Area:20.2
Heavy Atom Count:31
Complexity:760
Defined Atom Stereocenter Count:9
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes