2-(Trifluoromethyl)benzoic acid
-
2-(Trifluoromethyl)benzoic acid
structure -
-
CAS No:
433-97-6
-
Formula:
C8H5F3O2
-
Chemical Name:
2-(Trifluoromethyl)benzoic acid
-
Synonyms:
Benzoic acid,2-(trifluoromethyl)-;o-Toluic acid,α,α,α-trifluoro-;2-(Trifluoromethyl)benzoic acid;α,α,α-Trifluoro-o-toluic acid;o-(Trifluoromethyl)benzoic acid;NSC 88326
- Categories:
-
CAS No:
Description
slightly yellow to yellow-brown crystalline powder
2-(trifluoromethyl)benzoic acid is a benzoic acid carrying a trifluoromethyl substituent at the 2-position. It is a member of benzoic acids and a member of (trifluoromethyl)benzenes.
2-(Trifluoromethyl)benzoic acid Basic Attributes
190.12
190.12
976984
240-989-8
0R1CK7MZUA
88326
2916399090
Characteristics
37.3
1.3
Slightly yellow to yellow-brown Crystalline Powder
1.4±0.1 g/cm3
111 °C
247 °C753 mm Hg(lit.)
247-254°C
1.475
4.8g/L(25 ºC)
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
507mmHg at 25°C
Safety Information
IRRITANT
UN 1549 6.1/PG 3
2
20/22-51/53-36/37/38
61-36-26
Xn,N,Xi
Irritant
Stable at room temperature in closed containers under normal storage and handling conditions.
P261-P305 + P351 + P338
H315-H319-H335
2-(Trifluoromethyl)benzoic acid Use and Manufacturing
The preparation method is to add 2-chloro-trifluoromethylbenzene to the solvent tetrahydrofuran, then add magnesium metal at 55-60°C, add in batches to make Grignard reaction, and then add dry ice (carbon dioxide) in ether Stir the reaction to obtain the finished product.
O-Trifluoromethyl benzoic acid is an intermediate of the bactericide fluoroamide.
Benzoic acid, 2-(trifluoromethyl)-: ACTIVE|PMN - indicates a commenced PMN (Pre-Manufacture Notices) substance.
Computed Properties
Molecular Weight:190.12
XLogP3:1.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:190.02416388
Monoisotopic Mass:190.02416388
Topological Polar Surface Area:37.3
Heavy Atom Count:13
Complexity:200
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Recommended Suppliers of 2-(Trifluoromethyl)benzoic acid
-
![China]()
CN
5 YRS
Business licensedTrader Supplier of Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals,Biochemicals,Pharmaceuticals,Screening Compounds,Food Additives -
![China]()
CN
5 YRS
Business licensed Certified factoryManufactory Supplier of Active Pharm Ingredients,Chemical Catalyst,Pharmaceutical Intermediates,Flavors and Fragrances,Agrochemicals,Chemical Pesticides,Organic Intermediates,OLED IntermediatesInquiryCAS No.: 433-97-6Grade: Industrial GradeContent: 99% -
![China]()
CN
5 YRS
Business licensedTrader Supplier of PVC resin,pvc paste resin,melamineInquiryCAS No.: 433-97-6Grade: Industrial GradeContent: 99% -
![China]()
CN
4 YRS
Business licensedTrader Supplier of Semaglutide,Tirzepatide,API,EnzymeMore than 15 years GMP Factory Suppy 99.5% 2-(Trifluoromethyl)benzoic acid Medical Grade CAS433-97-6InquiryCAS No.: 433-97-6Grade: Pharmaceutical GradeContent: 99.5%
Learn More Other Chemicals
-
3,5-DIBROMO-2-[[[(3,5-DINITROBENZOYL)AMINO]THIOXOMETHYL]AMINO]-BENZOIC ACID
535965-38-9
-
3,5-DIBROMO-2-[[[[(2-CHLOROPHENOXY)ACETYL]AMINO]THIOXOMETHYL]AMINO]-BENZOIC ACID
532386-89-3
-
3,5-DIBROMO-2-[[[(4-METHYL-3-NITROBENZOYL)AMINO]THIOXOMETHYL]AMINO]-BENZOIC ACID
532943-48-9
-
3,5-DIBROMO-2-[[[[3-(2-FURANYL)-1-OXO-2-PROPENYL]AMINO]THIOXOMETHYL]AMINO]-BENZOIC ACID Formula
586392-09-8
-
3,5-DIBROMO-2-[[[[(2-METHYLPHENOXY)ACETYL]AMINO]THIOXOMETHYL]AMINO]-BENZOIC ACID Formula
531548-30-8
-
2-(1,8-dibromo-16,18-dioxo-17-azapentacyclo[6.6.5.0~2,7~.0~9,14~.0~15,19~]nonadeca-2,4,6,9,11,13-hexaen-17-yl)benzoic acid Formula
333340-54-8
-
3,5-DIBROMO-2-[[[[3-(PHENOXYMETHYL)BENZOYL]AMINO]THIOXOMETHYL]AMINO]-BENZOIC ACID Structure
586393-79-5
-
3,5-DIBROMO-2-[[[(4-CHLOROBENZOYL)AMINO]THIOXOMETHYL]AMINO]-BENZOIC ACID Structure
531530-32-2
-
What is 2-Cyclopentyl-3-(2,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-oxo-4-isoquinolinecarboxylic acid
400073-92-9
-
What is 9-Octadecenoic acid (9Z)-, compd. with N,N-dimethylcyclohexanamine (1:1)
65122-23-8