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5-ALPHA-ANDROSTANE

5-ALPHA-ANDROSTANE structure

CAS No:
438-22-2
Formula:
C19H32
Chemical Name:
5-ALPHA-ANDROSTANE
Synonyms:
5ALPHA-ANDROSTAN;5-ALPHA-ANDROSTANE;5ALPHA(H)-ANDROSTANE;5-A-ANDROSTANE;5-ALPHA-ANDROSTANE, 1X1ML, CH2CL2, 2000U G/ML;5alpha-androsane;5α-androstane;5-α-androstane solution
Categories:
Analytical Chemistry > Standard

Description

5alpha-androstane is the 5alpha-stereoisomer of androstane. It has a role as a human metabolite.

Purify 5-androstane by chromatography through Al2O3 (grade III) and elute with pet ether and recrystallise from MeOH (2x) and Me2CO/MeOH. It sublimes at 60o/high vacuum. Also dissolve it in pet ether, filter it through silica gel, evaporate and recrystallise it. [Steiger & Reichstein Helv Chim Acta 20 817 1937, Prelog et al. Helv Chim Acta 27 66 1944, IR, NMR: Halkes & Havinga Rec Trav Chim Pays-Bas 8 4 889 1965, Allinger et al. Tetrahedron 27 5073 1971, Beilstein 5 III 1110, 5 IV 1211.]

5-ALPHA-ANDROSTANE Basic Attributes

Molecular Weight：

260.46

Exact Mass：

260.46

EC Number：

207-116-2

UNII：

KT649U81FE

NSC Number：

49000

DSSTox ID：

DTXSID2036532

Color/Form：

White to Off-White

HScode：

29372290

Characteristics

PSA：

XLogP3：

8.42

Density：

0.950±0.06 g/cm3(Predicted)

Melting Point：

50-50.5°

Boiling Point：

336.0±9.0 °C(Predicted)

Flash Point：

145.9±12.3 °C

Refractive Index：

1.508

Storage Conditions：

room temp

Specific rotation：

D16 +2° (c = 1.2 in chloroform)

Critical Temperature & Pressure：

room temp

Safety Information

Transport codes：

UN15936.1/PG3

wgk germany：

hazard class code：

T,Xn

safety instructions：

53-23-24/25-36/37

Marks：

T,Xn

Precautionary statement(s)：

P261-P281-P305 + P351 + P338

Hazard Statements：

45-23/24/25-36/37/38-43-63-67-40

RIDADR：

UN 1593 6.1/PG 3

Drug Information

Biological Half-Life：

46.77 Days

MeSH Entry Terms：

5 alpha-androstane

5-ALPHA-ANDROSTANE Use and Manufacturing

Uses

5alpha-Androstane is an anabolic steroid.

Use Classification：

Lipids -> Sterol Lipids [ST] -> Steroids [ST02] -> C19 steroids (androgens) and derivatives [ST0202]

Computed Properties

Molecular Weight:260.5
XLogP3:7.6
Exact Mass:260.250401021
Monoisotopic Mass:260.250401021
Heavy Atom Count:19
Complexity:359
Defined Atom Stereocenter Count:6
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes