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Nobiletin

Nobiletin structure

Nobiletin 

structure
  • CAS No:

    478-01-3

  • Formula:

    C21H22O8

  • Chemical Name:

    Nobiletin

  • Synonyms:

    4H-1-Benzopyran-4-one,2-(3,4-dimethoxyphenyl)-5,6,7,8-tetramethoxy-;Flavone,3′,4′,5,6,7,8-hexamethoxy-;Nobiletin;2-(3,4-Dimethoxyphenyl)-5,6,7,8-tetramethoxy-4H-1-benzopyran-4-one;5,6,7,8,3′,4′-Hexamethoxyflavone;3′,4′,5,6,7,8-Hexamethoxyflavone;NSC 618903;NSC 76751;PMF 90;2-(3,4-Dimethoxyphenyl)-5,6,7,8-tetramethoxychromen-4-one

  • Categories:

    Cosmetic Ingredient  >  Antioxidant Ingredient

Description

Nobiletin is a citrus flavonoid with anti-inflammatory, anti-cancer, cholesterol lowering, memory protection activities.


Solid


Nobiletin is a methoxyflavone that is flavone substituted by methoxy groups at positions 5, 6, 7, 8, 3' and 4' respectively. It has a role as a plant metabolite and an antineoplastic agent. It derives from a flavone.

Nobiletin Basic Attributes

402.39

402.39

D65ILJ7WLY

618903|76751

DTXSID30197275

29329990

Characteristics

81.7

3

Solid

1.2±0.1 g/cm3

136.5-137.5 °C

587.9°C at 760 mmHg

256.5±30.2 °C

1.558

13.39 mg/L @ 25 °C (est)

-20°C

8.39E-14mmHg at 25°C

191.3 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

Safety Information

3

R36/37/38:Irritating to eyes, respiratory system and skin .

24/25

DJ3052200

Stable, but unstable if heated rapidly. Combustible. Incompatible with strong oxidizing agents, powdered aluminium, potassium.

Drug Information

Naturally occurring or synthetic substances that inhibit or retard oxidation reactions. They counteract the damaging effects of oxidation in animal tissues. (See all compounds classified as Antioxidants.)

hexamethoxyflavone

Nobiletin Use and Manufacturing

Uses

Chuanpisu has anti-hemagglutination, anti-thrombosis, anti-cancer, anti-fungal, anti-inflammatory, anti-inflammatory, anti-viral, anti-cancer, anti-mutation, anti-allergic, anti-ulcer, analgesic, blood pressure lowering activity, and lowering blood cholesterol. effect.

Polyketides [PK] -> Flavonoids [PK12] -> Flavones and Flavonols [PK1211]

Computed Properties

Molecular Weight:402.4
XLogP3:3
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:7
Exact Mass:402.13146766
Monoisotopic Mass:402.13146766
Topological Polar Surface Area:81.7
Heavy Atom Count:29
Complexity:593
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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